Manilith 450 SR Tablet
Prescription Required
Product introduction
Manilith 450 SR Tablet is used in the treatment of bipolar disorder and mania in adults. It is sometimes used to treat other behavioral disorders as well. It reduces the frequency of manic episodes and decreases the intensity of those episodes that might occur.
Manilith 450 SR Tablet should be taken with food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Do not skip any doses and finish the full course of treatment even if you feel better. If you have missed a dose, take it as soon as you remember it. You should continue to take this medicine for as long as the doctor advises and do not stop taking it suddenly as it may result in harmful effects.
Side effects associated with the use of this medicine include tremors, slurred speech, uncoordinated body movements, nausea, Vomiting, acne, increased white blood cell count, and memory impairment. It may also cause hair loss, enlarged thyroid gland, skin rash, and increased thirst. This medicine may also cause weight gain and to control it, you should have a balanced diet and exercise regularly. If you have been taking this medicine for a long time then regular monitoring of thyroid and kidney function may be required.
Uses of Manilith Tablet SR
Side effects of Manilith Tablet SR
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Manilith
- Tremors
- Slurred speech
- Uncoordinated body movements
- Nausea
- Acne
- Increased white blood cell count
- Memory impairment
- Hair loss
- Goiter (enlarged thyroid gland)
- Skin rash
- Increased thirst
- Weight gain
- Polyuria
- Diarrhea
- Vomiting
How to use Manilith Tablet SR
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Manilith 450 SR Tablet is to be taken with food.
How Manilith Tablet SR works
Manilith 450 SR Tablet works by suppressing the abnormal and excessive activity of the nerve cells in the brain.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Manilith 450 SR Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Manilith 450 SR Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Manilith 450 SR Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Manilith 450 SR Tablet may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Manilith 450 SR Tablet should be used with caution in patients with kidney disease. Dose adjustment of Manilith 450 SR Tablet may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Manilith 450 SR Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Manilith 450 SR Tablet may not be needed in these patients. Please consult your doctor.
What if you forget to take Manilith Tablet SR?
If you miss a dose of Manilith 450 SR Tablet, skip it and continue with your normal schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Manilith 450 SR Tablet is one of the most effective long-term treatment for bipolar disorder.
- It may also be used for the treatment of mania.
- Your lithium blood levels, thyroid function, and kidney function may be monitored as long as you take this medicine.
- It may cause diarrhea and dehydration. Drink plenty of water and and use normal amounts of salt. Inform your doctor if you start or stop a low-salt diet.
- Monitor your weight during treatment as Manilith 450 SR Tablet can cause weight gain.
- Do not drive or do anything that requires mental focus until you know how it affects you.
- Inform your doctor if you have persistent stomach upset, problems with your speech, or extreme drowsiness. Your dose may need to be adjusted.
- Do not take Manilith 450 SR Tablet if you are pregnant or breastfeeding.
- Do not stop taking the medication suddenly without talking to your doctor.
Fact Box
Chemical Class
Organic Carbonic Acids
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Mood Stabilizers
Interaction with drugs
Taking Manilith with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may affect heart rhythm and can be fatal.
Do not consume Domperidone with Lithium carbonate.
Concurrent use may cause serious disturbance in heart rhythm.
If concurrent use is essential, watch out for symptoms such as double vision, weakness, dizziness, impaired coordinat
Concurrent use may cause serious disturbance in heart rhythm.
Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart
Concurrent use may cause serious disturbance in heart rhythm.
Careful consideration is advised when taking Haloperidol with Lithium carbonate. If concurrent use is essential, watc
Concomitant use may affect heart rhythm and can be fatal.
Do not consume Hydroxyzine with Lithium carbonate.
Patient concerns
FAQs
How quickly does Manilith 450 SR Tablet work?
It takes some time before you see improvement in your symptoms after taking Manilith 450 SR Tablet. Though it varies from person to person, it may take 1-3 weeks or longer for you to see the full benefits of Manilith 450 SR Tablet. Do not stop taking Manilith 450 SR Tablet if you feel you are not improving. Instead, discuss it with your doctor.
Does Manilith 450 SR Tablet make you sleepy?
Yes, Manilith 450 SR Tablet can cause nervous system disorders like sleepiness and dizziness and feeling confused. It can also cause rapid eye movements, blurred vision, or blind spots in your eyesight. If you experience any of these symptoms, consult your doctor. In addition, avoid driving or operating heavy machinery as it can be hazardous for you.
Is Manilith 450 SR Tablet bad for kidneys?
Yes, Manilith 450 SR Tablet may cause kidney problems. Manilith 450 SR Tablet is not prescribed in patients who already have severe kidney impairment. The kidney problems may not be reversible and the symptoms include swollen ankles, passing a lot of urine and feeling thirsty. Before starting treatment with Manilith 450 SR Tablet, your doctor will get blood tests done to see if your kidney function is normal. During Manilith 450 SR Tablet therapy, any gradual or sudden changes in renal function, even within the normal range, may indicate the need for re-evaluation of treatment.
Can Manilith 450 SR Tablet cause gain in weight?
Manilith 450 SR Tablet can cause both weight gain or weight loss. You should keep a check on your weight during Manilith 450 SR Tablet therapy. If you feel you are gaining or losing too much weight, consult your doctor who will assess whether the change in weight is due to Manilith 450 SR Tablet or some other reason.
What is the most important information I should know about Manilith 450 SR Tablet?
Manilith 450 SR Tablet therapy should only be started if adequate facilities for assessing Manilith 450 SR Tablet levels are available. This is because Manilith 450 SR Tablet toxicity is related to increased levels of Manilith 450 SR Tablet in blood. Manilith 450 SR Tablet toxicity can even occur at dose which is effective for treatment. Therefore, your doctor may closely monitor your Manilith 450 SR Tablet levels weekly until stabilization is achieved, then weekly for one month and then at monthly intervals thereafter.
How should Manilith 450 SR Tablet be taken?
Take Manilith 450 SR Tablet exactly as prescribed by your doctor. Check with your doctor if you are not sure. It is meant for oral administration and can be taken with or without food. However, if you start following a certain type of diet, talk to your doctor first. Any drastic changes in the amount of water you drink or amount of sodium (salt) in your diet may require more frequent monitoring of Manilith 450 SR Tablet levels.
Which medicines decrease Manilith 450 SR Tablet levels?
You should inform your doctor about the medicines you are taking before starting Manilith 450 SR Tablet since many medicines interfere with the working of Manilith 450 SR Tablet. Some medicines decrease the levels of Manilith 450 SR Tablet in blood which means that it will not work well. These include theophylline (for asthma), caffeine, anything containing sodium bicarbonate, or a special group of diuretics (water tablets) called carbonic anhydrase inhibitors and urea used to treat skin conditions.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Stahl SM, editor. Lithium. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 349-54.
- Meltzer H. Antipsychotic Agents & Lithium. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 502-504.
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Lithium. [Updated 2020 Jan 20]. [Accessed 20 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
- Lithium Carbonate [Patient Information Leaflet]. Ahmedabad, Gujarat: Torrent Pharmaceuticals :Ltd.; 2022. [Accessed 20 Feb. 2024] (online) Available from:
Marketer details
Name: Psychocare Health Pvt Ltd
Address: Supreet Singh (Director) SCO 34-35, 1st Floor, New Sunny Enclave Market, Behind KFC, Sector 125, Greater Mohali
Country of origin: India
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