Mantaglial 5 Tablet
Prescription Required
Product introduction
Mantaglial 5 Tablet is a medicine used in the treatment of Alzheimer's disease. It helps to slow down the progression of moderate to severe Alzheimer's disease by improving memory and thinking. This medicine works by blocking a chemical messenger involved in the transmission of nerve signals.
Mantaglial 5 Tablet maybe taken with or without food. However, it is advised to take it at the same time each day to maintain a consistent level of medicine in the blood. If you missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor.
The most common side effects of this medicine are dizziness, headache, confusion, and constipation. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.
Before taking this medicine, inform the doctor if you have a history of seizures, kidney disease, heart disease, or liver disease. Let your doctor also know if you are taking any other medicines for any medical conditions. Pregnant and breastfeeding women should consult their doctors before taking this medicine.
Uses of Mantaglial Tablet
Side effects of Mantaglial Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Mantaglial
- Dizziness
- Headache
- Confusion
- Constipation
How to use Mantaglial Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mantaglial 5 Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Mantaglial Tablet works
Mantaglial 5 Tablet is an N-methyl-D-aspartate (NMDA) receptor antagonist. Memory loss in Alzheimer’s disease is due to excessive production of glutamate (chemical messenger) in the brain which is mediated by NMDA receptors. Mantaglial 5 Tablet works by preventing the action of NMDA receptors and regulates the production of glutamate. involved in the transmission of nerve signals. This is how it prevents memory loss in Alzheimer’s disease.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Mantaglial 5 Tablet. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Mantaglial 5 Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Mantaglial 5 Tablet during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Mantaglial 5 Tablet may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Mantaglial 5 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Mantaglial 5 Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Mantaglial 5 Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Mantaglial 5 Tablet may be needed. Please consult your doctor.
Limited information is available on the use of Mantaglial 5 Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
Limited information is available on the use of Mantaglial 5 Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
What if you forget to take Mantaglial Tablet?
If you miss a dose of Mantaglial 5 Tablet, skip it and continue with your normal schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- You have been prescribed Mantaglial 5 Tablet to treat dementia (memory loss) in patients with Alzheimer's disease.
- It is well tolerated and has lesser side effects as compared to other similar medicines.
- Be cautious while driving or doing anything that requires concentration until you know how Mantaglial 5 Tablet affects you.
- Inform your doctor if you have a history of seizures, kidney disease, heart disease, or liver disease.
- Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
- You have been prescribed Mantaglial 5 Tablet to slow down the progression of Alzheimer's disease.
- It is well tolerated and has lesser side effects as compared to other similar medicines.
- Be cautious while driving or doing anything that requires concentration until you know how Mantaglial 5 Tablet affects you.
- Inform your doctor if you have a history of seizures, kidney disease, heart disease, or liver disease.
- Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
Fact Box
Chemical Class
Amantadine Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
NMDA (N-methyl-D-aspartate) Receptor Antagonists
Interaction with drugs
Taking Mantaglial with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Memantine may reduce efficacy of Aripiprazole.
Your doctor may monitor your treatment and adjust the doses as per the observations.
Memantine may reduce efficacy of Amisulpride.
Your doctor may monitor your treatment and adjust the doses as per the observations.
Memantine may reduce efficacy of Amisulpride.
Your doctor may monitor your treatment and adjust the doses as per the observations.
If taken together, Amantadine may decrease the absorption of Memantine.
Do not consume Memantine with Amantadine. If concurrent use is essential, your doctor may monitor your trea
Memantine may reduce efficacy of Chlorpromazine.
Your doctor may monitor your treatment and adjust the doses as per the observations.
Patient concerns
FAQs
Does Mantaglial 5 Tablet have abuse potential?
No, Mantaglial 5 Tablet does not have abuse potential. On the contrary, it may prevent excess use of addictive drugs such as morphine or ethanol.
When and how Mantaglial 5 Tablet should be taken?
Mantaglial 5 Tablet should be taken orally once a day. To benefit from your medicine you should take it regularly every day at the same time of the day. The tablets should be swallowed with some water. The tablets can be taken with or without food.
How long does it take for Mantaglial 5 Tablet to start working?
For Mantaglial 5 Tablet to start working and show its full benefits, it may require between 3 and 8 hours. The doctor may require a follow-up clinical assessment to check the progress after 4 weeks and then 6 months after the first assessment.
What are the symptoms of overdosage of Mantaglial 5 Tablet?
The symptoms which can be observed due to an overdose of Mantaglial 5 Tablet include tiredness, weakness, drowsiness, confusion, hallucinations, and/or vomiting. Some may also experience diarrhea, vertigo, agitation, aggression, and walking difficulty.
How does Mantaglial 5 Tablet affect a person with dementia?
Mantaglial 5 Tablet belongs to a class of medications called N-methyl-D- aspartate (NMDA) receptor antagonists. It works by decreasing abnormal activity in the brain. Mantaglial 5 Tablet may improve the ability to think and remember. It may also reduce the deterioration of these abilities in people who have Alzheimer's disease. However, with time the effectiveness of this medicine will reduce and it may not be able to cure Alzheimer's disease or prevent the loss of these abilities.
What is dementia?
Dementia is a syndrome in which there is deterioration in memory, thinking, behavior, and the ability to perform everyday activities. Dementia is one of the major causes of disability and dependency among older people worldwide. Alzheimer disease is the most common form of dementia which contributes to around 60 to 70% of cases.
Can I just stop taking Mantaglial 5 Tablet?
No, Mantaglial 5 Tablet should not be stopped even if you feel well. This medicine only helps to control the symptoms of Alzheimer's disease but does not cure it. If you need to stop the medication then doctor should be consulted first.
Does Mantaglial 5 Tablet make you sleepy?
Yes, Mantaglial 5 Tablet may make you sleepy. Mantaglial 5 Tablet has minor to moderate influence on the ability to drive and usage of machines. In such cases, outpatients should be warned to take special care.
Can Mantaglial 5 Tablet be combined with donepezil?
Yes, Mantaglial 5 Tablet can be combined with donepezil, as there will be no increased adverse effects. However, this combination will not cure Alzheimer's, but it can only improve thinking ability, short term memory, and other related symptoms.
What medicines should I avoid while taking Mantaglial 5 Tablet?
Mantaglial 5 Tablet can interact with several medicines. Taking other medicines along with Mantaglial 5 Tablet can either make Mantaglial 5 Tablet less effective or increase its side effect. Do not take any medicine without talking to your doctor.
Does Mantaglial 5 Tablet have any interaction with cardiac medicines?
Yes, Mantaglial 5 Tablet may interfere with the working of hydrochlorothiazide (HCT). It decreases the levels of HCT which will reduce the effectiveness of HCT. Also, procainamide and quinidine may increase levels of Mantaglial 5 Tablet which may cause increased toxicity.
Can I stop taking Mantaglial 5 Tablet if I feel better?
No, keep using Mantaglial 5 Tablet as advised by your doctor, even if you feel well. Stopping Mantaglial 5 Tablet can bring back your symptoms of dementia.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Katzung BG. Special Aspect of Geriatric Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 1141-42.
- Standaert DG, Roberson ED. Treatment of Central Nervous System Degenerative Disorders. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 622.
- Stahl SM, editor. Memantine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 397-400.
- Memantine HCl. Dublin, Ireland: Forest Laboratories Ireland Ltd.; 2003 [revised Oct 2013]. [Accessed 25 Jan. 2019] (online) Available from:
- Memantine hydrochloride [EMC SmPC]. Hatfield, Hertfordshire: Generics UK T/A Mylan; 2013 [revised Jun. 2015]. [Accessed 25 Mar 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation. Memantine. [Accessed 11 Jul. 2023]. (online) Available from:
- Memantine Hydrochloride [Patient Information Leaflet]. Bachupally, India: Dr. Reddy’s Laboratories Limited. [Accessed 11 Jul. 2023]. (online) Available from:
- Memantine hydrochloride [Prescribing Information]. Panchmahal, Gujarat: Alembic Pharmaceuticals Limited (Formulation Division); 2023. [Accessed 11 Jul. 2023]. (online) Available from:
Marketer details
Name: Glial Life Science LLP
Address: address is 7, Kishan Park 2, Opp. Ami Akhandanand Soc. Near. Purvadip Soc. Amraiwadi, Ahemdabad Ahmedabad Gj 380026 In
Country of origin: India
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