Mefegesic 250mg/500mg Tablet is a combination of two medicines. It is used in the treatment of fever. It is also useful for the treatment of mild to moderate pain of various conditions like headache, body ache, and toothache.

Mefegesic 250mg/500mg Tablet is to be taken with food. This will prevent you from getting an upset stomach. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.

The most common side effects of this medicine include nausea, vomiting, diarrhea, indigestion, loss of appetite, and heartburn. If any of these side effects bother you or get worse, you should speak to your doctor. Your doctor may be able to suggest ways of preventing or reducing the side effects.

Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

Uses of Mefegesic Tablet

Benefits of Mefegesic Tablet

In Pain relief

Mefegesic 250mg/500mg Tablet is a combination of medicines used to treat aches and pains. It blocks chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis and muscle aches.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time.

In Treatment of Fever

Mefegesic 250mg/500mg Tablet is also used to reduce a high temperature (fever). It works by blocking the release of certain chemical messengers that cause fever. It may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor.

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Side effects of Mefegesic Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Mefegesic

Nausea
Vomiting
Diarrhea
Indigestion
Loss of appetite
Heartburn

How to use Mefegesic Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mefegesic 250mg/500mg Tablet is to be taken with food.

How Mefegesic Tablet works

Mefegesic 250mg/500mg Tablet is a combination of two medicines: Mefenamic Acid and Paracetamol. It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Mefegesic 250mg/500mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Mefegesic 250mg/500mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Mefegesic 250mg/500mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving

UNSAFE

Mefegesic 250mg/500mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Mefegesic 250mg/500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Mefegesic 250mg/500mg Tablet may be needed. Please consult your doctor.
Use of Mefegesic 250mg/500mg Tablet is not recommended in patients with severe kidney disease.

Liver

CAUTION

Mefegesic 250mg/500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Mefegesic 250mg/500mg Tablet may be needed. Please consult your doctor.
However, the use of Mefegesic 250mg/500mg Tablet is not recommended in patients with severe liver disease and active liver disease.

What if you forget to take Mefegesic Tablet?

If you miss a dose of Mefegesic 250mg/500mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Mefegesic 250mg/500mg Tablet

₹3.01/Tablet

Meftec P 250mg/500mg Tablet

Zeotec Life Science Pvt Ltd

₹3.17/tablet

5% costlier

Mefdel P 250mg/500mg Tablet

Delwis Healthcare Pvt Ltd

₹3.15/tablet

5% costlier

Neopan Tablet

Noel Pharma India Pvt Ltd

₹5/tablet

66% costlier

Mafnagesic Tablet

Wockhardt Ltd

₹2.43/tablet

19% cheaper

LENAGESIC 250MG/500MG TABLET

Wockhardt Ltd

₹1.98/tablet

34% cheaper

View all substitutes

Quick tips

Mefegesic 250mg/500mg Tablet is used to reduce pain and swelling in various conditions.
Take it with food to prevent an upset stomach.
It may cause dizziness and sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you.
If you get diarrhea while taking this medicine, stop taking it and consult your doctor.
Avoid consuming alcohol while taking Mefegesic 250mg/500mg Tablet as it can cause excessive drowsiness and increase your risk of stomach problems.
Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.
Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough-and-cold) without asking your doctor first.
Mefegesic 250mg/500mg Tablet is used to reduce pain and swelling in various conditions.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Patient concerns

fever and 2 months pregnant can take combiflan

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

No take Crocin for pain relief

Diagnosed with viral fever along with rashes on the body. Pain in eyes since three days. Pain when open and when blinking.

Dr. Richa Jain

Ophthalmology

Orbital pain is common with viral fever. Go to physician for fever. It will be relieved with relief in fever

FAQs

Q. Is it safe to use Mefegesic 250mg/500mg Tablet?

Yes, Mefegesic 250mg/500mg Tablet is safe to use in most of the patients. However, in some patients it may cause some unwanted common side effects like nausea, vomiting, stomach pain, heartburn, diarrhea and other uncommon and rare side effects. Inform your doctor if you experience any persistent problem due to the medication.

Q. Can Mefegesic 250mg/500mg Tablet be stopped when the pain is relieved?

Mefegesic 250mg/500mg Tablet is usually used for short term and can be discontinued when the pain is relieved. However, if advised by the doctor, it should be continued for the recommended time period.

Q. Can the use of Mefegesic 250mg/500mg Tablet cause nausea and vomiting?

Yes, the use of Mefegesic 250mg/500mg Tablet can cause nausea and vomiting. Taking it with milk, food or antacids can prevent nausea. Avoid taking fatty or fried foods along with the medicine. In the case of vomiting, drink plenty of water or other fluids by taking small and frequent sips. Talk to the doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to your doctor.

Q. Can the use of Mefegesic 250mg/500mg Tablet cause dizziness?

Yes, the use of Mefegesic 250mg/500mg Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better. Do not drive or use any machines.

Q. Are there any specific contraindications associated with the use of Mefegesic 250mg/500mg Tablet?

The use of Mefegesic 250mg/500mg Tablet is considered to be harmful for patients with known allergy to any of the components or excipients of this medicine or in patients with known allergy to other painkillers (NSAIDs). The use of this medicine should preferably be avoided in patients with a history of stomach ulcer or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with a history of liver or kidney disease.

Q. Can I take Mefegesic 250mg/500mg Tablet with vitamin B-complex?

Yes, Mefegesic 250mg/500mg Tablet can be taken with Vitamin B-complex preparations. While Mefegesic 250mg/500mg Tablet helps to relieve pain, Vitamin B-complex can help correct the vitamin deficiency that might be causing the underlying painful condition.

Q. Can the use of Mefegesic 250mg/500mg Tablet cause damage to kidneys?

Yes, the long-term use of Mefegesic 250mg/500mg Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protect the kidneys from damage. Use of painkillers lower the levels of prostaglandins in the body which leads to kidney damage on long-term use. Use of painkillers is not recommended to patients with underlying kidney disease.

Q. Is it safe to take a higher than the recommended dose of Mefegesic 250mg/500mg Tablet?

No, taking a higher than the recommended dose of Mefegesic 250mg/500mg Tablet can increase the risks of side effects like nausea, vomiting, heartburn, indigestion, diarrhea and can also damage the kidneys on long-term use. If you are experiencing increased severity of pain or the pain is not relieved by the recommended doses, please consult your doctor for re-evaluation.

Q. What are the storage condition for Mefegesic 250mg/500mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

FDA approved prescribing information. Mefenamic Acid; 2008 [revised Mar. 2007]. [Accessed 02 Apr. 2019] (online) Available from:
ScienceDirect. Mefenamic Acid. [Accessed 02 Apr. 2019] (online) Available from:
ScienceDirect. Paracetamol/Acetaminophen. [Accessed 23 Apr. 2019] (online) Available from:

Marketer details

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Address: JOGEO Building P.T. Road Kakkanad Cochin - 682 021 Kerala India

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.