Megalep 400mg Tablet CR belongs to a group of medicines called anti-epileptics. It is used to treat two conditions – epilepsy and bipolar disorder. It also helps in the prevention of migraine. This way it prevents extreme mood swings and abnormal brain signals that trigger seizures (fits).

Megalep 400mg Tablet CR can be used alone or in combination with other medicines. It may be taken with or without food. Your doctor will decide the correct dose for you. This may increase gradually until your condition is stable. This medicine may take several weeks to work but it is important to take it regularly to get the benefit. Do not stop taking it, even if you feel fine, unless your doctor advises you to. You may have more seizures, or your bipolar disorder may get worse.

The most common side effects of this medicine include skin rashes, headache, feeling or being sick, difficulty sleeping, dizziness, and feeling sleepy or drowsy. Most side effects wear off, but if they bother you or do not go away, tell your doctor. There may be ways of preventing or reducing these effects. Long-term treatment can cause weakness in your bones (osteoporosis), increasing your risk of breaking a bone.

Before taking this medicine, tell your doctor if you have kidney or liver problems, meningitis or depression, or suicidal thoughts. Also let your healthcare team know about all other medications you are using as some may affect, or be affected by, this medicine, including contraceptive pills. If you are pregnant or breastfeeding, the dose may be adjusted. You should avoid driving or riding a bicycle if this medicine makes you drowsy or dizzy. You may need frequent blood tests to check how you are responding to this medicine.

Uses of Megalep Tablet CR

Benefits of Megalep Tablet CR

In Epilepsy/Seizures

Megalep 400mg Tablet CR helps prevent and control seizures (fits) by decreasing the nerve impulses which cause the seizures. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. It helps reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety.
This medicine is not associated with any physical or psychological dependence (addiction) but it should not be stopped suddenly. It must be taken regularly as prescribed to be effective. Missing doses may trigger a seizure.

In Prevention of Migraine

It is not fully established how Megalep 400mg Tablet CR helps prevent migraines. It may change the abnormal and excessive activity of the nerve cells in the brain or increase the activity in a region of the brain associated with migraines. By preventing and reducing the frequency of headaches, it can help you carry out your daily activities and have a better quality of life.

In Bipolar disorder

Megalep 400mg Tablet CR works to restore the normal balance of nerve activity in your brain. It can help prevent extreme changes in mood and help you feel less agitated. You may experience fewer episodes of low mood. It can take several weeks for this medicine to work and you may still feel low during this time. It is likely that you will take this medicine for at least six months but possibly much longer. It needs to be taken regularly to work effectively. Do not stop taking it unless your doctor advises you to. You should continue to eat well and keep fit to reduce symptoms of bipolar disorder.

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Side effects of Megalep Tablet CR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Megalep

Headache
Dizziness
Blurred vision
Loss of appetite
Nausea
Vomiting
Sleepiness
Hair loss
Weight gain
Double vision
Diarrhea
Impaired coordination
Tremors
Weakness
Stomach pain
Increased appetite

How to use Megalep Tablet CR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Megalep 400mg Tablet CR may be taken with or without food, but it is better to take it at a fixed time.

How Megalep Tablet CR works

Megalep 400mg Tablet CR is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Megalep 400mg Tablet CR. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Megalep 400mg Tablet CR is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Megalep 400mg Tablet CR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Megalep 400mg Tablet CR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Megalep 400mg Tablet CR should be used with caution in patients with kidney disease. Dose adjustment of Megalep 400mg Tablet CR may be needed. Please consult your doctor.

Liver

UNSAFE

Megalep 400mg Tablet CR is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

What if you forget to take Megalep Tablet CR?

If you miss a dose of Megalep 400mg Tablet CR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Megalep 400mg Tablet CR

₹10.2/Tablet CR

Magprol CR 400 Tablet

Intas Pharmaceuticals Ltd

₹13.4/tablet cr

31% costlier

Quick tips

It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Monitor your weight during treatment with this medicine as it can cause weight gain.
Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
Some healthy tips to prevent seizures:
- Practice yoga every day.
- Get enough sleep at nighttime.
- Limit the use of screen time such as mobile/laptop.
- Take your medication on time.

Fact Box

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Sodium channel modulators (AED)

Patient concerns

Treatment about bipolar disorder

Dr. Ravi Shankar M.

Ayurveda

Tab. Manasa Mitra Vataki 1-0-1 and Kalyanaka Ghritam 10 gram twice a day with luke warm wtar after food and Sarswatharishta 15 ml twice a day with equal quantity of water for 2 months

Suffering from bipolar disorder

Dr. Jyoti Kapoor Madan

Psychiatry

Bipolar Affective Disorder is a chronic problem caused by Neuro chemical disturbance in brain. It is characterised by excessive mood swings leading to disruption in routine life. Treatment is with mood stabilizer medicines and antipsychotic medicines which may need to continue throughout life. Please see a psychiatrist for further guidance.

Bipolar disorder treatment needed

Dr. Jyoti Kapoor Madan

Psychiatry

FAQs

For how long should I take Megalep 400mg Tablet CR to cure my epilepsy completely?

Megalep 400mg Tablet CR does not cure your condition, it only prevents the seizures from occurring. Therefore, you will have to keep on taking it, maybe for years. Consult your doctor if face any problems while taking this medicine.

What happens if I stop taking Megalep 400mg Tablet CR?

You should not stop taking Megalep 400mg Tablet CR suddenly. It should be discontinued gradually. Stopping it suddenly may increase the chances of recurrence of seizures. Always consult your doctor if you feel the need to stop taking this medicine.

I have gained weight after I started using Megalep 400mg Tablet CR. Is it because of this medicine? What should I do?

Yes, weight gain can occur with the use of Megalep 400mg Tablet CR. To control your weight, you should have a healthy balanced diet and exercise regularly. Talk to your doctor if you have any other concerns.

Can I take birth control pills while taking Megalep 400mg Tablet CR?

Yes, Megalep 400mg Tablet CR does not have any effect on the working of birth control pills. However, contraceptives (birth control pills) may interfere with the working of Megalep 400mg Tablet CR and seizures may occur. It is important that you inform your doctor that you are using birth control pills. Your doctor will keep a track on your response to the treatment and monitor the Megalep 400mg Tablet CR levels in your blood levels.

Is it safe to take Megalep 400mg Tablet CR for long term?

Many patients can safely take Megalep 400mg Tablet CR for a long time. Rarely, long-term use of Megalep 400mg Tablet CR may weaken your bones, thereby increasing their chances of breaking easily (osteoporosis and osteopenia). If you are taking Megalep 400mg Tablet CR for a long time, get regular check ups done for bone health.

I am concerned because I have heard that Megalep 400mg Tablet CR causes hair loss. Is it true?

Megalep 400mg Tablet CR may cause thinning of hair, change of hair colour and even hair loss. If you are concerned talk to your doctor if it is possible to reduce the dose of Megalep 400mg Tablet CR. Your hair may regrow after either reducing your dose or switching to a different medicine.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:

Marketer details

Name: Ryon Pharma

Address: Village Ajnoud Ludhiana - 141421, Punjab, India

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.