Megsafe 10mg/10mg/5mg Tablet is a combination medicine used in the treatment of nausea or vomiting during pregnancy. It blocks signals to reach the brain that trigger the feeling of nausea and vomiting.

Megsafe 10mg/10mg/5mg Tablet is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are dryness in the mouth, constipation, and lightheadedness. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine can also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.

Uses of Megsafe Tablet

Treatment of Nausea and vomiting in pregnancy

Benefits of Megsafe Tablet

In Treatment of Nausea and vomiting in pregnancy

Megsafe 10mg/10mg/5mg Tablet blocks the action of chemicals in the body that can make you feel or be sick during pregnancy. This medicine helps you cope up with nausea or vomiting that occurs due to hormonal changes during pregnancy and helps you complete the term without much discomfort. It also contains nutritional supplements that improve your baby’s immune system, enhance the baby’s brain development and also help reduce nausea and vomiting during pregnancy.

Side effects of Megsafe Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Megsafe

Sleepiness
Dizziness
Fatigue
Dryness in mouth
Constipation

How to use Megsafe Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Megsafe 10mg/10mg/5mg Tablet is to be taken with food.

How Megsafe Tablet works

Megsafe 10mg/10mg/5mg Tablet is a combination of three medicines: doxylamine, vitamin B6 (pyridoxine) and folic acid, which treats nausea and vomiting associated with pregnancy.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Megsafe 10mg/10mg/5mg Tablet. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Megsafe 10mg/10mg/5mg Tablet is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.

Breast feeding

SAFE IF PRESCRIBED

Megsafe 10mg/10mg/5mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Larger doses or prolonged use of Megsafe 10mg/10mg/5mg Tablet may cause sleepiness and other effects in the baby

Driving

UNSAFE

Megsafe 10mg/10mg/5mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Megsafe 10mg/10mg/5mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Megsafe 10mg/10mg/5mg Tablet may not be needed in these patients. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Megsafe 10mg/10mg/5mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Megsafe 10mg/10mg/5mg Tablet may not be needed in these patients. Please consult your doctor.

What if you forget to take Megsafe Tablet?

If you miss a dose of Megsafe 10mg/10mg/5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Megsafe 10mg/10mg/5mg Tablet

₹5.33/Tablet

Doxifit Tablet

Olympus Life Sciences

₹6.97/tablet

31% costlier

Folidex Tablet

Gennext Life Sciences

₹4.65/tablet

13% cheaper

Pregvom Plus 10mg/10mg/5mg Tablet

Intas Pharmaceuticals Ltd

₹0.8/tablet

85% cheaper

Pregfresh Tablet

Cerspin Healthcare Pvt Ltd

₹4.16/tablet

22% cheaper

Ems Tablet

Maan Pharmaceuticals Ltd

₹3.38/tablet

37% cheaper

View all substitutes

Quick tips

Megsafe 10mg/10mg/5mg Tablet helps treat nausea and vomiting in pregnant women whose symptoms did not improved using diet and lifestyle changes.
Take it on an empty stomach with a glass of water.
It may cause dizziness. Do not drive or do anything requiring concentration until you know how it affects you.
Do not take it with other sedating medications such as cough and cold medications as the combination could worsen dizziness leading to falls or other accidents

Fact Box

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Patient concerns

Not eating. Vomiting wt we do.

Dr. Megha Tuli

Obstetrics and Gynaecology

Avoiding fluids including tea and water right early in the morning will help. Ginger also helps with the nausea and vomiting of pregnancy.

She miss her period since last 12 days & upt is postitive . Patient having abdominal pain , vomiting , nausea , weakness , fainting .

Dr. Suman Rao

Obstetrics and Gynaecology

These are the normal symptoms of pregnancy. She can take treatment for nausea and vomiting after consulting a Gynae

I am in the first month of pregnancy and I am experiencing nausea, vomiting, stomach pain (moderate to severe) as well as discomfort. Current medications is Susten SR 200 (OD), Duvadilan retard (OD), Doxinate (BD), Folverine D (OD), Fertigyn 500 (1 amp weekly) and aciloc 150 (BD). What should I do to ease my situation. Please suggest

Dr. Suman Rao

Obstetrics and Gynaecology

The med suggested are to support of pregnancy and for acidity and nausea and vomiting. Continue the same. You can upgrade the med for vomiting after consulting your

I m in 5th week of pregnancy feeling dizziness n nausea several times of a day is it normal or take any precautions or medicine

Dr. Megha Tuli

Obstetrics and Gynaecology

Hi PATIENT on your good news! Yes nausea and mild vomiting and dizziness is common in early pregnancy. Please maintain a good hydration. Take plenty of fluids during the day. If vomiting is too much you must see a doctor. All the best.

FAQs

Q. What are the instructions for storage and disposal of Megsafe 10mg/10mg/5mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it at as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. Can I take a higher than the recommended dose of this medicine?

No, taking a higher than the recommended dose of Megsafe 10mg/10mg/5mg Tablet can cause increased side effects. If you are experiencing increased severity of nausea or vomiting, which is not relieved by the recommended doses, please consult your doctor for re-evaluation.

Q. Can the use of Megsafe 10mg/10mg/5mg Tablet cause drowsiness or sleepiness?

Yes, one of the common side effects of Megsafe 10mg/10mg/5mg Tablet is drowsiness. Do not drive, operate heavy machinery or engage in other activities that need your full attention. Do not drink alcohol or take any medicines that may depress the central nervous system like cough and cold medicines, certain pain medicines, and medicines that help you sleep, while you are taking Megsafe 10mg/10mg/5mg Tablet. Severe drowsiness can happen or it can become worse and cause falls or accidents.

Q. Can the use of Megsafe 10mg/10mg/5mg Tablet cause dry mouth?

Yes, the use of Megsafe 10mg/10mg/5mg Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. Try to avoid foods that are acidic (like lemons), spicy and salty.

Q. Can a pregnant woman take Megsafe 10mg/10mg/5mg Tablet?

Yes, it is safe to take Megsafe 10mg/10mg/5mg Tablet in pregnant women. In fact, this medicine is used to treat nausea and vomiting in pregnant women. It is mainly recommended to those women whose symptoms have not improved after changing their diet or using other non-medicine treatments.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Doxylamine succinate and pyridoxine hydrochloride. Blainville, Québec: Duchesnay Inc.; 1976 [revised Nov. 2016]. [Accessed 12 Apr. 2019] (online) Available from:
DailyMed. Doxylamine succinate and pyridoxine hydrochloride. [Accessed 12 Apr. 2019] (online) Available from:
ScienceDirect. Vitamin B6. [Accessed 12 Apr. 2019] (online) Available from:
DailyMed. Pyridoxine hydrochloride. [Accessed 12 Apr. 2019] (online) Available from:
Folic Acid. Maidenhead: Intrapharm Laboratories Limited; 2011 [revised 8 May 2018]. [Accessed 12 Apr. 2019] (online) Available from:

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