Memo-G Tablet is a medicine used in the treatment of Alzheimer's disease. It helps to slow down the progression of moderate to severe Alzheimer's disease by improving memory and thinking. This medicine works by blocking a chemical messenger involved in the transmission of nerve signals.
Memo-G Tablet maybe taken with or without food. However, it is advised to take it at the same time each day to maintain a consistent level of medicine in the blood. If you missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor.
The most common side effects of this medicine are dizziness, headache, confusion, and constipation. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.
Before taking this medicine, inform the doctor if you have a history of seizures, kidney disease, heart disease, or liver disease. Let your doctor also know if you are taking any other medicines for any medical conditions. Pregnant and breastfeeding women should consult their doctors before taking this medicine.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Memo-G
Dizziness
Headache
Confusion
Constipation
How to use Memo-G Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Memo-G Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Memo-G Tablet works
Memo-G Tablet is an N-methyl-D-aspartate (NMDA) receptor antagonist. Memory loss in Alzheimer’s disease is due to excessive production of glutamate (chemical messenger) in the brain which is mediated by NMDA receptors. Memo-G Tablet works by preventing the action of NMDA receptors and regulates the production of glutamate. involved in the transmission of nerve signals. This is how it prevents memory loss in Alzheimer’s disease.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Memo-G Tablet. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Memo-G Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Memo-G Tablet during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Memo-G Tablet may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Memo-G Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Memo-G Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Memo-G Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Memo-G Tablet may be needed. Please consult your doctor. Limited information is available on the use of Memo-G Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
What if you forget to take Memo-G Tablet?
If you miss a dose of Memo-G Tablet, skip it and continue with your normal schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Do not consume Memantine with Amantadine. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
If taken together, A... More
No, Memo-G Tablet does not have abuse potential. On the contrary, it may prevent excess use of addictive drugs such as morphine or ethanol.
When and how Memo-G Tablet should be taken?
Memo-G Tablet should be taken orally once a day. To benefit from your medicine you should take it regularly every day at the same time of the day. The tablets should be swallowed with some water. The tablets can be taken with or without food.
How long does it take for Memo-G Tablet to start working?
For Memo-G Tablet to start working and show its full benefits, it may require between 3 and 8 hours. The doctor may require a follow-up clinical assessment to check the progress after 4 weeks and then 6 months after the first assessment.
What are the symptoms of overdosage of Memo-G Tablet?
The symptoms which can be observed due to an overdose of Memo-G Tablet include tiredness, weakness, drowsiness, confusion, hallucinations, and/or vomiting. Some may also experience diarrhea, vertigo, agitation, aggression, and walking difficulty.
How does Memo-G Tablet affect a person with dementia?
Memo-G Tablet belongs to a class of medications called N-methyl-D- aspartate (NMDA) receptor antagonists. It works by decreasing abnormal activity in the brain. Memo-G Tablet may improve the ability to think and remember. It may also reduce the deterioration of these abilities in people who have Alzheimer's disease. However, with time the effectiveness of this medicine will reduce and it may not be able to cure Alzheimer's disease or prevent the loss of these abilities.
What is dementia?
Dementia is a syndrome in which there is deterioration in memory, thinking, behavior, and the ability to perform everyday activities. Dementia is one of the major causes of disability and dependency among older people worldwide. Alzheimer disease is the most common form of dementia which contributes to around 60 to 70% of cases.
Can I just stop taking Memo-G Tablet?
No, Memo-G Tablet should not be stopped even if you feel well. This medicine only helps to control the symptoms of Alzheimer's disease but does not cure it. If you need to stop the medication then doctor should be consulted first.
Does Memo-G Tablet make you sleepy?
Yes, Memo-G Tablet may make you sleepy. Memo-G Tablet has minor to moderate influence on the ability to drive and usage of machines. In such cases, outpatients should be warned to take special care.
Can Memo-G Tablet be combined with donepezil?
Yes, Memo-G Tablet can be combined with donepezil, as there will be no increased adverse effects. However, this combination will not cure Alzheimer's, but it can only improve thinking ability, short term memory, and other related symptoms.
What medicines should I avoid while taking Memo-G Tablet?
Memo-G Tablet can interact with several medicines. Taking other medicines along with Memo-G Tablet can either make Memo-G Tablet less effective or increase its side effect. Do not take any medicine without talking to your doctor.
Does Memo-G Tablet have any interaction with cardiac medicines?
Yes, Memo-G Tablet may interfere with the working of hydrochlorothiazide (HCT). It decreases the levels of HCT which will reduce the effectiveness of HCT. Also, procainamide and quinidine may increase levels of Memo-G Tablet which may cause increased toxicity.
Can I stop taking Memo-G Tablet if I feel better?
No, keep using Memo-G Tablet as advised by your doctor, even if you feel well. Stopping Memo-G Tablet can bring back your symptoms of dementia.
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References
Katzung BG. Special Aspect of Geriatric Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 1141-42.
Standaert DG, Roberson ED. Treatment of Central Nervous System Degenerative Disorders. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 622.
Stahl SM, editor. Memantine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 397-400.
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