Meval 500mg Tablet ER is a medicine used to treat epilepsy. It helps prevent and control seizures (fits). It is also used in the prevention of migraines. Occasionally, it may also be used to treat bipolar disorder.

Meval 500mg Tablet ER may be used alone or in combination with other medicines. The dose and how often you need to take it will be decided by your doctor so that you get the right amount to control your symptoms. You can take this medicine with or without food but take it at the same time each day to get the most benefit.

It usually takes a couple of weeks to work. It is important to take this medicine regularly and for as long as you are advised, even if you feel well. Missing doses may trigger seizures and, if you stop, your condition may get worse. It should never be stopped suddenly.

This medicine's most common side effects include headache, blurred vision, nausea, vomiting, dizziness, tiredness, unsteadiness, bruising, and decreased body temperature. Most of these are not serious. Keep taking the medicine but talk to your doctor if these side effects bother you or do not go away. However, if you notice a skin rash or redness, tell your doctor straight away. Long-term treatment with this medicine can cause osteoporosis (reduced bone mass) and increase your risk of breaking a bone. Also, Meval 500mg Tablet ER may rarely lead to suicidal thoughts and behaviors. If your mood becomes depressed, tell your doctor.

This medicine may not be suitable for everybody. Before using it, tell your doctor if you have ever had heart problems, kidney or liver disease, difficulty urinating, depression, or suicidal thoughts. Many other medicines can interfere with it and some should not be taken together so tell your doctor all the medicines you are taking to make sure it is safe. If you are pregnant, do not start or stop taking this medicine without asking your doctor. Drinking alcohol should be avoided as it can increase some of the side effects and can also increase your risk of seizures. You may need frequent blood tests to help your doctor make sure you are taking the right dose both before you start and while you are using it.

Uses of Meval Tablet ER

Benefits of Meval Tablet ER

In Treatment of Epilepsy/Seizures

Meval 500mg Tablet ER is an anticonvulsant (or anti-epileptic) medicine that works by decreasing the nerve impulses which cause the seizures. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. It helps reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety.
This medicine is not associated with any physical or psychological dependence (addiction) but it should not be stopped suddenly. It must be taken regularly as prescribed to be effective. Missing doses may trigger a seizure.

In Treatment of Bipolar disorder

Meval 500mg Tablet ER works to restore the normal balance of nerve activity in your brain. It can help prevent extreme changes in mood and help you feel less agitated. You may experience fewer episodes of low mood. It can take several weeks for this medicine to work and you may still feel low during this time. It is likely that you will take this medicine for at least six months but possibly much longer. It needs to be taken regularly to work effectively. Do not stop taking it unless your doctor advises you to. You should continue to eat well and keep fit to reduce symptoms of bipolar disorder.

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Side effects of Meval Tablet ER

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Meval

Decreased body temperature
Dizziness
Sleepiness
Tremors
Paresthesia (tingling or pricking sensation)
Anemia (low number of red blood cells)
Decreased sodium level in blood
Liver injury
Gastrointestinal disturbance
Hypersensitivity
Deafness
Urinary incontinence
Increase in body weight
Pain during periods

How to use Meval Tablet ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Meval 500mg Tablet ER may be taken with or without food, but it is better to take it at a fixed time.

How Meval Tablet ER works

Meval 500mg Tablet ER is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

Safety advice

Alcohol

UNSAFE

Meval 500mg Tablet ER may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Meval 500mg Tablet ER is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Meval 500mg Tablet ER is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving

UNSAFE

Meval 500mg Tablet ER may cause side effects which could affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Meval 500mg Tablet ER is safe to use in patients with kidney disease. No dose adjustment of Meval 500mg Tablet ER is recommended.

Liver

UNSAFE

Meval 500mg Tablet ER is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

What if you forget to take Meval Tablet ER?

If you miss a dose of Meval 500mg Tablet ER, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Meval 500mg Tablet ER

₹8.91/Tablet ER

Dicorate ER 500 Tablet

Sun Pharmaceutical Industries Ltd

₹21.9/tablet er

146% costlier

Divaa -OD 500 Tablet ER

Intas Pharmaceuticals Ltd

₹19.95/tablet er

124% costlier

Desval ER 500 Tablet

Eris Lifesciences Ltd

₹19.37/tablet er

117% costlier

Divalgress ER 500 Tablet

La Renon Healthcare Pvt Ltd

₹15.2/tablet er

71% costlier

Depakote XR 500 Tablet

Sanofi India Ltd

₹26.14/tablet er

193% costlier

View all substitutes

Quick tips

Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
It can be taken with or without food, but better to take with food to avoid stoamch upset.
Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
Some healthy tips to prevent seizures:
- Practice yoga every day.
- Get enough sleep at nighttime.
- Limit the use of screen time such as mobile/laptop.
- Take your medication on time.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Monitor your weight during treatment with this medicine as it can cause weight gain.
Your doctor may get regular blood tests done to monitor how the medication is affecting your body. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
Meval 500mg Tablet ER helps in the treatment and prevention of seizures.
Take it at the same time every day to maintain consistent levels in your body.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking Meval 500mg Tablet ER, as it may cause excessive sleepiness or drowsiness.
Monitor your weight during treatment with this medicine as it can cause weight gain.
Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
Do not take Meval 500mg Tablet ER if you are pregnant or planning to conceive or breastfeeding.
Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
Some healthy tips to prevent seizures:
- Practice yoga every day.
- Get enough sleep at nighttime.
- Limit the use of screen time such as mobile/laptop.
- Take your medication on time.
It may increase the risk of low sodium levels in the blood. Inform your doctor if you develop difficulty concentrating, memory problems, confusion, weakness, and unsteadiness.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.

Fact Box

Chemical Class

Aliphatic Carboxylic acid Derivatives

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Sodium Channel Modulators- Antiepileptic drugs (AEDs)

Patient concerns

She has problem of epilepsy from last two years

Dr. Rahul Yadav

Paediatrics

Hello, epilepsy and seizures cannot be treated online without physically examining the child and detailed history.

Left side headache while laughing or coughing for 20 seconds only Pls suggest

Dr. Pushkar Mani

Physician

could be trigeminal neuralgia/ TM joint stifness or migrainerefer to ENT doctor and Neurophysician

Hi I am suffering from epilepsy from the past 1.5 years but before that I have no issues with my health the symptoms are I will get vomiting sensation from evening & heavy body pains & fits will comes only in early morning from 4 & 5 am i will get un concious for about 20 or 30 minutes & I will bite my tongue & after that I will have heavy nerve pains for a day or two from 5 days I am taking encorte 500 tablets between day & night before that I used to take homeopathy treatment

Dr. Jyoti Kapoor Madan

Psychiatry

Epilepsy is a central nervous system disorder (neurological disorder) in which nerve cell activity in the brain becomes disrupted, causing seizures or periods of unusual behavior, sensations and sometimes loss of consciousness. Medicines for epilepsy are initially recommended for at least 3 years of seizure free interval but may continue longer depending on recurrence. Epileptic patient needs to carry a warning card or a medical emergency bracelet with identification details, his/ her epilepsy status and what people can do if fit occurs in public place.

I am Epilepsy peshent said u take tab Phen Phen 50 up to 3 to 5 years

Dr. Jyoti Kapoor Madan

Psychiatry

I m taking 1.5gm sodium valporate,1.5 levectram, 1gm clobezam then also seizure r their at period of weekly is there alternate treatment in Ayurveda as every time at multiplying the doses at every visit As MRI eeg every tests r normal

Dr. M. K. Ansari

Neurology

not aware of any ayurvedic medications for epilepsy is not my specialization. However you seems to have difficult to control (intractable) seizures plz follow doctors advice deligently for ur own welfare

FAQs

What happens if I stop taking Meval 500mg Tablet ER?

You should not stop taking Meval 500mg Tablet ER without consulting your doctor. The dose of Meval 500mg Tablet ER should be reduced gradually and eventually can be stopped under the supervision of a doctor or specialist. Suddenly stopping the medication may lead to recurrence of symptoms or irritability, anxiety, dizziness and tremors.

Is Meval 500mg Tablet ER a mood stabilizer?

Yes, Meval 500mg Tablet ER can sometimes be used as a mood stabilizer. It is given in patients who experience rapid changes in their mood. It works by calming the hyperactivity of the brain during mood changes.

Can Meval 500mg Tablet ER cause weight gain?

Yes, Meval 500mg Tablet ER may cause weight gain. The gain in weight could be due to an increase in hunger. Keep a check on your diet and exercise regularly to prevent any weight gain. If you are have concerns related to weight gain, consult your doctor.

Does Meval 500mg Tablet ER make you sleepy?

Yes, Meval 500mg Tablet ER may make you feel sleepy. Avoid driving or other work that requires mental focus until you know how it affects you.

Does Meval 500mg Tablet ER cause hair loss?

Yes, Meval 500mg Tablet ER may cause hair loss. However, it is only for a short time and is usually dose related. Please consult your doctor if the hair loss bothers you or persists for a longer duration.

Can Meval 500mg Tablet ER damage my liver?

Yes, Meval 500mg Tablet ER can cause damage to the liver. The risk is more likely to occur during the first 6 months of starting the treatment with Meval 500mg Tablet ER. Symptoms of liver damage may include nausea or vomiting, loss of appetite, stomach pain, dark coloured urine, facial swelling, yellowing of the skin or white of eyes. Therefore, it is important to have liver function tests done before starting the medicine and. Tests should be done periodically during the first 6 months of therapy, especially in those who are likely to be at risk and those with a prior history of liver disease.

Can I take alcohol while I am taking Meval 500mg Tablet ER?

Avoid alcohol consumption while you are on treatment with Meval 500mg Tablet ER. Taking alcohol with this medicine may make you feel more drowsy, light headed or dizzy.

What are the laboratory tests recommended prior to taking Meval 500mg Tablet ER?

The doctor may suggest blood tests before starting the treatment with Meval 500mg Tablet ER. The tests may include blood cell count, including platelet count, bleeding time and coagulation tests These tests are also advised to avoid any spontaneous bruising or bleeding. In addition to this, liver function tests are advised before therapy. It is recommended to periodically monitor liver function during the first 6 months of therapy, primarily in those who seem most at risk and those with a prior history of liver disease.

What should be done if I start experiencing abdominal pain, nausea and anorexia?

If you experience acute severe abdominal pain along with nausea and vomiting, it may be due to pancreatitis. Immediately consult your doctor in case you experience these symptoms. Your doctor may get your levels of serum amylase checked. In case the test shows positive results for pancreatitis, the medication should be stopped immediately.

How to check for overdose of Meval 500mg Tablet ER?

Overdose of Meval 500mg Tablet ER may cause headaches, blurred eyesight due to pupils of the eyes becoming smaller, lack of reflexes, confusion and tiredness. You may also experience weak or “floppy” muscles, fits (seizures), loss of consciousness, behavioral changes and breathing difficulties such as fast breathing, shortness of breath, or chest pain. Immediate medical assistance is required in case of overdose.

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References

Divalproex sodium. North Chicago: AbbVie Inc; 1983 [revised Feb. 2016]. [Accessed 22 Mar. 2019] (online) Available from:
Divalproex sodium. North Chicago, IL: Abbott Laboratories; 2006. [Accessed 22 Mar. 2019] (online) Available from:
Divalproex sodium [Medication Guide]. Halol, Gujarat: Sun Pharmaceutical Industries Ltd.; 2022. [Accessed 20 June 2023]. (online) Available from:
Divalproex sodium [Prescribing Information]. Ghaziabad, UP: Unichem Laboratories Ltd.; 2023. [Accessed 20 June 2023]. (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:

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