Nacel 1000mg Injection is an antidote medication. It is used in the treatment of paracetamol overdose (when you may have taken too much paracetamol medicine). It protects your liver and helps to reduce the extent of the injury.

Nacel 1000mg Injection is given as an injection under the supervision of a doctor. It must be injected within 8 hours of a paracetamol overdose. It can be given up to 24 hours, but the medicine’s effectiveness slows down when given after 24 hours of the overdose. Your doctor will decide how much you need to improve your symptoms. Always follow your doctor's advice while taking this medicine.

The most common side effects of this medicine include rash, urticaria, flushing, and itching. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.

Before taking this medicine, let your doctor know if you suffer from asthma, as close monitoring is required while taking this medicine. Your doctor should also know about all other medicines you are taking, as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Uses of Nacel Injection

Treatment of Paracetamol toxicity

Benefits of Nacel Injection

In Treatment of Paracetamol toxicity

Nacel 1000mg Injection is an antidote medicine that prevents serious side effects if a person has taken more than the normal or recommended amount of a medicine called paracetamol. Paracetamol overdose may cause serious liver damage, which may even lead to liver failure. Rarely, an excessive overdose may lead to a coma. Nacel 1000mg Injection is given as an injection by a doctor or nurse and should not be self-administered. Follow your doctor’s instructions carefully to get the most benefit from this medication.

Side effects of Nacel Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nacel

Rash
Red spots or bumps
Flushing (sense of warmth in the face, ears, neck and trunk)

How to use Nacel Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Nacel Injection works

Nacel 1000mg Injection is an antidote for paracetamol poisoning. It works by increasing the level of glutathione, an antioxidant that neutralizes the toxic products of paracetamol. Glutathione helps the liver safely break down and remove harmful substances formed when paracetamol is taken in excessive amounts. If glutathione levels drop too low, these toxic substances can cause severe liver damage. By restoring glutathione, Nacel 1000mg Injection protects liver cells and reduces the risk of serious harm.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Nacel 1000mg Injection. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Nacel 1000mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

CAUTION

Nacel 1000mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Driving

CONSULT YOUR DOCTOR

It is not known whether Nacel 1000mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

SAFE IF PRESCRIBED

Nacel 1000mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nacel 1000mg Injection may not be needed in these patients. Please consult your doctor.

Liver

CAUTION

Nacel 1000mg Injection should be used with caution in patients with severe liver disease. Dose adjustment of Nacel 1000mg Injection may be needed. Please consult your doctor.

What if you forget to take Nacel Injection?

If you miss a dose of Nacel 1000mg Injection, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Nacel 1000mg Injection

₹116/Injection

Mucomix 1gm Injection

Samarth Life Sciences Pvt Ltd

₹132.32/injection

11% costlier

Mucomelt 1000mg Injection

Venus Remedies Ltd

₹130.52/injection

9% costlier

Coenac 1000 Solution

Koye Pharmaceuticals Pvt ltd

₹117.77/injection

2% cheaper

Mucotroy Injection 5ml

Troikaa Pharmaceuticals Ltd

₹113.84/injection

5% cheaper

Mucyst 1000mg Injection

Neon Laboratories Ltd

₹123.5/injection

3% costlier

View all substitutes

Quick tips

Do not wait for symptoms to appear—seek medical help immediately after a suspected overdose.
Let your doctor know if you have asthma or a history of stomach ulcers, as precautions may be needed.
After treatment, follow-up blood tests may be required to check liver function.
Always keep paracetamol out of reach of children to prevent accidental overdose.
Nacel 1000mg Injection protects the liver from damage by the high levels of paracetamol.

Fact Box

Chemical Class

N-Acylated Alpha Amino Acids

Habit Forming

Therapeutic Class

OTHERS

Action Class

Mucolytics

Patient concerns

Is there any toxic effect for the drug garoin(phenobarbitone and phenytoin) in constipation child If the child doesnot having epilepsy also??

Dr. Gopal Bansilal Samdani

Paediatrics

Toxicity is dose dependent

Ferrous sulphate tablets toxicity

Dr. Megha Tuli

Obstetrics and Gynaecology

There is no toxicity as such. Please be specific in what respect are you asking.

Sir rahul yadav paediatric prefer a medicine ARACHITOL SACHET. but that is not availabale any medical & online also please can you prefer any other medicine for my female child. She is so slim age is 18 months still she is not walking properly. Weght is 8 kg only. I also give her calcimax p and zincovit

Dr. Gopal Bansilal Samdani

Paediatrics

Please do Vit D test and if needed then only give supplement as excess can cause toxicity

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FAQs

What is Nacel 1000mg Injection used for?

Nacel 1000mg Injection is mainly used to treat paracetamol (acetaminophen) overdose. It helps protect the liver from serious damage by breaking down harmful substances formed when too much paracetamol is taken.

How soon should Nacel 1000mg Injection be given after a paracetamol overdose?

For best results, Nacel 1000mg Injection should be given as soon as possible—ideally within 8 hours of the overdose. It can still help if given up to 24 hours later, but the sooner it is given, the better the chances of preventing liver damage.

How is Nacel 1000mg Injection given?

Nacel 1000mg Injection is usually given in a hospital through a drip (intravenous infusion) into a vein. The dose and duration depend on the amount of paracetamol taken and how long it has been since the overdose. The doctor will monitor closely during the treatment to ensure safety and effectiveness.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 13-15.
Acetylcysteine (N-Acetylcysteine). In: Hitchings A, Lonsdale D, Burrage D, et al., editors. The Top 100 Drugs: Clinical Pharmacology and Practical Pescribng. Churchil Livingstone Elsevier; 2015.
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Acetylcysteine [Prescribing Information]. Nashville, Tennessee: Cumberland Pharmaceuticals Inc.; 2013. [Accessed 31 Jan. 2019] (online) Available from:
Acetylcysteine Injection [Prescribing Information]. Lake Zurich, IL: Fresenius Kabi; 2018. [Accessed 09 Jun 2023] (online) Available from:
Acetadote® (acetylcysteine) Injection [Package insert]. Nashville, TN: Cumberland Pharmaceuticals Inc.; 2006. [Accessed 10 Feb 2025] (online) Available from: