Nacel 400mg Injection
Prescription Required
Product introduction
Nacel 400mg Injection is an antidote medication. It is used in the treatment of paracetamol overdose (when you may have taken too much paracetamol medicine). It protects your liver and helps to reduce the extent of the injury.
Nacel 400mg Injection is given as an injection under the supervision of a doctor. It must be injected within 8 hours of paracetamol overdose. It can be given up to 24 hours, but medicine effective slow down when given after 24 hours of dosage overdose. Your doctor will decide how much you need to improve your symptoms. Always follow your doctor's advice while taking this medicine.
The most common side effects of this medicine include rash, urticaria, flushing, and itching. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.
Before taking this medicine let your doctor know if you suffer from asthma, as close monitoring is required while taking this medicine. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.
Nacel 400mg Injection is given as an injection under the supervision of a doctor. It must be injected within 8 hours of paracetamol overdose. It can be given up to 24 hours, but medicine effective slow down when given after 24 hours of dosage overdose. Your doctor will decide how much you need to improve your symptoms. Always follow your doctor's advice while taking this medicine.
The most common side effects of this medicine include rash, urticaria, flushing, and itching. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.
Before taking this medicine let your doctor know if you suffer from asthma, as close monitoring is required while taking this medicine. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.
Uses of Nacel Injection
- Treatment of Paracetamol toxicity
Benefits of Nacel Injection
In Treatment of Paracetamol toxicity
Nacel 400mg Injection is an antidote medicine that prevents serious side effects if a person has taken more than the normal or recommended amount of a medicine called paracetamol which leads to an overdose. Initially, there may be mild gastrointestinal symptoms like nausea, vomiting, stomach pain, irritability, etc. But, if left untreated, paracetamol overdose may cause serious liver damage, which may even lead to liver failure. Rarely, an excessive overdose may lead to a coma. It is given as an injection by a doctor or nurse and should not be self-administered. Follow your doctor’s instructions carefully to get the most benefit from this medication.
Side effects of Nacel Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nacel
- Rash
- Red spots or bumps
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Itching
How to use Nacel Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Nacel Injection works
Nacel 400mg Injection is an antidote for paracetamol poisoning. It works by increasing the level of glutathione, an antioxidant that neutralises the toxic products of paracetamol.
Safety advice
Alcohol
SAFE
Consuming alcohol with Nacel 400mg Injection does not cause any harmful side effects.
Pregnancy
SAFE IF PRESCRIBED
Nacel 400mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Nacel 400mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
SAFE
Nacel 400mg Injection does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Nacel 400mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nacel 400mg Injection may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Nacel 400mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Nacel 400mg Injection may not be needed in these patients. Please consult your doctor.
What if you forget to take Nacel Injection?
If you miss a dose of Nacel 400mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Nacel 400mg Injection
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Quick tips
- Nacel 400mg Injection is used for the treatment of paracetamol overdose (when you may have taken too much paracetamol).
- It protects the liver from damage by the high levels of paracetamol.
- It is very effective when given during the first 8 hours following paracetamol overdose. The effectiveness is reduced with time but it can still help when given within 24 hours.
Fact Box
Chemical Class
N-Acylated Alpha Amino Acids
Habit Forming
No
Therapeutic Class
OTHERS
Action Class
Acetylcysteine -Mucolytic
Patient concerns
User feedback
How much was the improvement?
Excellent
100%
What were the side-effects while using Nacel 400mg Injection?
No Side Effec*
100%
*No Side Effect
FAQs
Is Nacel 400mg Injection good for liver?
Yes, Nacel 400mg Injection is good for the liver. It improves liver function and activity in patients with non-alcoholic fatty liver disease. It also prevents liver from toxic agents which can damage the liver. Additionally, it also prevents liver from damage in cases of drug overdose like paracetamol, etc.
Does Nacel 400mg Injection affect blood pressure?
Yes, Nacel 400mg Injection by acting through various mechanism prevents the rise of blood pressure and maintains the normal functioning of the body. There are reports which show that Nacel 400mg Injection can prevent damage to the inner lining of the blood vessels of the body, which will maintain the elasticity and vitality of the blood vessels. It also increases the antioxidants levels in the body hence preventing the body from oxidative damage.
Does Nacel 400mg Injection help anxiety?
There is no concrete evidence that Nacel 400mg Injection can be used alone in the treatment of anxiety disorder. However, in some reports, it is shown that Nacel 400mg Injection provides benefit by acting as an antioxidant. This property prove to be beneficial in psychiatric and neurological conditions when added to the normal treatment of the particular disorder. Do not take this medication without consulting your doctor. Contact the doctor for any query if you feel anxious.
Is Nacel 400mg Injection good for kidneys?
Yes, Nacel 400mg Injection is beneficial when used in patients with impaired kidney functions. It is also used to prevent or minimize the damage caused by the use of contrast during investigations like CT scan or other body scans.
Does Nacel 400mg Injection need to be refrigerated?
Unopened vials of Nacel 400mg Injection should be stored at room temperature. Once the medicine is opened and diluted it should be used within 3 hours as per the directions of the physician. It should not be stored above 25ºC. Once opened, the vials should be stored in refrigeration and if unused then should be discarded after 96 hours.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 13-15.
- Acetylcysteine (N-Acetylcysteine). In: Hitchings A, Lonsdale D, Burrage D, et al., editors. The Top 100 Drugs: Clinical Pharmacology and Practical Pescribng. Churchil Livingstone Elsevier; 2015.
- Acetylcysteine. Romford, Essex: Martindale Pharma; 2004 [revised 23 Feb. 2017]. [Accessed 01 Apr. 2019] (online) Available from:
- Acetylcysteine. Nashville, Tennessee: Cumberland Pharmaceuticals Inc.; 2004 [revised Jun. 2013]. [Accessed 31 Jan. 2019] (online) Available from:
- Acetylcysteine Injection [Prescribing Information]. Lake Zurich, IL: Fresenius Kabi; 2018. [Accessed 09 Jun, 2023] (online) Available from:
Marketer details
Name: Celon Laboratories Ltd
Address: Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081
Country of origin: India
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