Nacsafe-XP Tablet is a combination medicine used to relieve pain and swelling in various conditions like muscle pain, joint pain, and postoperative pain. Thus, it effectively alleviates pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis.

Nacsafe-XP Tablet should be taken in the dose and duration as advised by your doctor. It should be taken with food or milk to prevent stomach upset. Taking the medicine regularly at the right times increases its effectiveness. It is important to keep taking the medicine regularly until your doctor tells you it is safe to stop.

Nausea, vomiting, stomach pain, indigestion, heartburn, increased liver enzymes, dizziness,
drowsiness, and diarrhea are some of the common side effects that might be observed on taking this medicine. Your doctor may regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment. Long-term use may lead to serious complications such as stomach bleeding and kidney problems. Nacsafe-XP Tablet is not recommended if you are pregnant or breastfeeding.

Uses of Nacsafe-XP Tablet

Pain relief

Benefits of Nacsafe-XP Tablet

In Pain relief

Nacsafe-XP Tablet is a combination medicine used for short-term relief of pain, inflammation, and swelling in conditions affecting joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis. Along with painkillers, this medicine also contains an active ingredient called Serratiopeptidase, which is an enzyme that promotes the overall healing process and speeds up recovery.

Take it as it is prescribed to get the most benefit. Do not take more or longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Nacsafe-XP Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nacsafe-XP

Nausea
Vomiting
Stomach pain
Indigestion
Heartburn
Loss of appetite
Diarrhea
Dizziness
Increased liver enzymes
Drowsiness

How to use Nacsafe-XP Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nacsafe-XP Tablet is to be taken with food.

How Nacsafe-XP Tablet works

Nacsafe-XP Tablet is a combination of three medicines: Aceclofenac, Paracetamol and Serratiopeptidase. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID), and Paracetamol is an antipyretic (fever reducer). They work by blocking the release of certain chemical messengers in the brain that cause pain and fever. Serratiopeptidase is an enzyme which works by breaking down abnormal proteins at the site of inflammation and promotes healing.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Nacsafe-XP Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Nacsafe-XP Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Nacsafe-XP Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Nacsafe-XP Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Nacsafe-XP Tablet should be used with caution in patients with kidney disease. Dose adjustment of Nacsafe-XP Tablet may be needed. Please consult your doctor.
Use of Nacsafe-XP Tablet is not recommended in patients with severe kidney disease.

Liver

CAUTION

Nacsafe-XP Tablet should be used with caution in patients with liver disease. Dose adjustment of Nacsafe-XP Tablet may be needed. Please consult your doctor.
However, the use of Nacsafe-XP Tablet is not recommended in patients with severe liver disease and active liver disease.

What if you forget to take Nacsafe-XP Tablet?

If you miss a dose of Nacsafe-XP Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Nacsafe-XP Tablet

₹6.08/Tablet

Zerodol-SP Tablet

Ipca Laboratories Ltd

₹13.7/tablet

125% costlier

Signoflam Tablet

Lupin Ltd

₹13.9/tablet

129% costlier

Dolowin Forte Tablet

Micro Labs Ltd

₹15.5/tablet

155% costlier

Dolokind AA Tablet

Mankind Pharma Ltd

₹11/tablet

81% costlier

Willgo SP Tablet

Panacea Biotec Pharma Ltd

₹6.84/tablet

12% costlier

View all substitutes

Quick tips

You have been prescribed this combination medicine for relieving pain and inflammation.
Take it with food to avoid getting an upset stomach.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how Nacsafe-XP Tablet affects you.
Avoid consuming alcohol when taking Nacsafe-XP Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first.

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Patient concerns

Hello i have low sperm count 6.0 mill/Ml my doctor has prescribed me Carni Q XP is it good ?

Dr. Shyam Gupta

Obstetrics and Gynaecology

Hello this is good medicine

My baby is 7 month old he is suffering from cold what dosage shall i give him of zerotuss xp

Dr. Rahul Yadav

Paediatrics

Hello, cold medicines are not recommended routinely for any child less than 9 months of age. Start nasoclear nasal drops SOS for nasal blockage. Also syp Alerid 2.5 ml once daily for the next 5 days.

I am suffering from typhoid since 2 days. I have been taken1. tab.calpol 2.tab.cefexime 200mg 3.inj xone-xp .now no response. Please give me some advice.

Dr. Deepak Kumar Soni

Ayurveda

https://goo.gl/forms/5QhDt8ZurRhhcjvD2 Kindly fill the health informationHi first complete your alloapathic medicine course then you can continue Patanjali Giloyghan vatiOne ?one tablet morning & evening after taking food , use at least 1-2 months

My baby is suffering from fever and high cough from last 2 days. I am giving xyzalM, zero tussle xp, duet 2285 Ds prescribed by doctor. Fever is coming in every 5 hour. Baby couldn't sleep due to cough and fever as well.

Dr. Gopal Bansilal Samdani

Paediatrics

Dr need a final diagnosis or provisional diagnosis to suggest you investigations or medicine or give opinion. Diagnosis cannot be done without taking in to consideration details of history and findings of clinical examination of patient. Advice given without doing clinical examination can be imperfect or some time harmful to patientThere are many underlying causes of your symptoms. Different cause needs different treatment. Specific treatment cannot be given unless we establish exact underlying cause. Final and perfect diagnosis cannot be done without doing clinical examination of child. Please consult me or any other Paediatrician. will take detail history and will examine your child in detail. All information will be used to determine exact underlying cause of problem. Depending upon cause will prescribe you treatment. At time may ask you relevant investigations if necessary.

FAQs

What is Nacsafe-XP Tablet?

It is a combination of three medicines: Aceclofenac, Paracetamol, and Serratiopeptidase. This medication helps in relieving pain and inflammation. It works by lowering the levels of chemical substances in the body that cause pain and inflammation.

Is it safe to take Nacsafe-XP Tablet?

It is safe to take this medicine for most of the patients. However, in some patients, it may cause unwanted side effects like nausea, vomiting, stomach pain, heartburn, and diarrhea. If you experience any persistent problem due to the medication, inform your doctor as soon as possible.

Can I stop taking Nacsafe-XP Tablet when my pain is relieved?

This medicine is usually used for the short term and can be discontinued when your pain is relieved. However, continued taking it if your doctor has advised you to do so.

Can Nacsafe-XP Tablet cause nausea and vomiting?

Yes, the use of this medicine can cause nausea and vomiting. In case you experience nausea while taking this medicine, take it with milk, food, or with antacids. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicines without speaking to your doctor.

Can Nacsafe-XP Tablet cause dizziness?

Yes, the use of this medicine can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for sometime and resume once you feel better.

Are there any specific contraindications associated with taking Nacsafe-XP Tablet?

The use of this medicine is considered harmful for patients with known allergy to any of the components or excipients of this medicine or in patients with known allergy to other painkillers (NSAIDs). Its use should preferably be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcers/bleeding. It should also be avoided in patients with a history of heart failure, high blood pressure, and liver or kidney disease.

Can I take Nacsafe-XP Tablet with vitamin B-complex?

Yes, this medicine can be taken with vitamin B-complex preparations. While it helps to relieve pain, vitamin B-complex can help to correct the vitamin deficiency that might be causing your symptoms.

Can the use of Nacsafe-XP Tablet cause damage to kidneys?

Yes, long-term use of this medicine can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protect them from damage. The use of painkillers lowers the levels of prostaglandins in the body, which leads to kidney damage on long-term use. The use of painkillers is not recommended in patients with underlying kidney disease.

Can I take a higher dose of Nacsafe-XP Tablet than recommended?

No, taking a higher than recommended dose can lead to increased chances of side effects. If you are experiencing increased severity of pain or the pain is not relieved by the recommended doses, please consult your doctor for re-evaluation.

What are the instructions for storage and disposal of Nacsafe-XP Tablet?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Bhagat S, Agarwal M, Roy V. Serratiopeptidase: A systematic review of the existing evidence. Int J Surg. 2013;11(3):209-17. [Accessed 19 Apr. 2019] (online) Available from:
Taj Life Sciences. Aceclofenac, Paracetamol and Serratiopeptidase [Product Information]. [Accessed 12th Sept. 2023] (online) Available from:

Marketer details

Name: Sanes Pharmaceuticals

Address: 11K, Nanakpura, Kuldeep Nagar, Ambala Cantt, Haryana 133004

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.