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MBA, MD Pharmacology
Last updated
19 Nov 2024 | 01:10 AM (IST)

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Nalox 400mcg Injection

Prescription Required

Product introduction

Nalox 400mcg Injection is an opioid antagonist. It is used for the treatment of opioid toxicity. It helps to reverse the depressant effect on breathing, and on other parts of the body. It also helps to determine if a patient has taken an overdose of opioids.

Nalox 400mcg Injection is given as an injection into veins, muscle, or under the skin by a doctor or nurse. It is advisable not to self-administer the injection. Your doctor or nurse will train your family member or caregiver about how to inject the medicine in case of an emergency. It is advisable to follow your doctor's advice while being on the treatment. 

The most common side effects of this medicine include injection site redness, dizziness, headache and increased or decreased blood pressure. Most of these usually go away within a short time of the injection. If you are bothered by them or they go on for longer, talk to your doctor or nurse. You should not drive if this medicine makes you feel dizzy. 

Before taking it, tell your doctor if you have heart problems, high blood pressure, or high heart rate. This may affect your treatment. Pregnant or breastfeeding women should consult their doctor before taking this medicine.  Some other medicines you are taking may interfere with it, so make sure your doctor knows about all the other medicines you are using.

Uses of Nalox Injection

  • Opioid toxicity

Benefits of Nalox Injection

In Opioid toxicity

Opioid toxicity or opioid overdose can be life-threatening and requires immediate medical attention. It is most commonly seen in people who take opioids containing painkillers or those who are indulged in drug abuse. Nalox 400mcg Injection helps to reverse the effects of opioid toxicity such as reduced breathing, confusion, lessened alertness, and loss of consciousness.
Nalox 400mcg Injection is given as an injection by a doctor or a nurse and should not be self-administered. If you are a caregiver to a person who is on opioids, you need to be trained well by a healthcare professional to administer Nalox 400mcg Injection in case there is an emergency and you do not have access to medical services immediately.

Side effects of Nalox Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nalox

  • Dizziness
  • Injection site redness
  • Decreased blood pressure
  • Headache
  • High blood pressure

How to use Nalox Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Nalox Injection works

Nalox 400mcg Injection is an opioid antagonist. Opioid medicines are strong painkillers, which in high doses can cause life-threatening side effects such as difficulty in breathing. Nalox 400mcg Injection works by blocking the effects of opioids leading to reversal of these side effects.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Nalox 400mcg Injection.
Pregnancy
SAFE IF PRESCRIBED
Nalox 400mcg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Nalox 400mcg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
SAFE
Nalox 400mcg Injection does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Nalox 400mcg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nalox 400mcg Injection may not be needed in these patients. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Nalox 400mcg Injection in patients with liver disease. Please consult your doctor.

What if you forget to take Nalox Injection?

If you miss a dose of Nalox 400mcg Injection, please consult your doctor.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Nalox 400mcg Injection
₹83.5/Injection
Nex 400mcg Injection
Neon Laboratories Ltd
₹102/injection
21% costlier

Quick tips

  • It is given as an injection into veins, muscle or under the skin by the healthcare professionals only.
  • Nalox 400mcg Injection might make you feel dizzy. If this happens, avoid driving or operating on machinery.
  • Inform the doctor if you are taking any pain killers, sleeping pills (sedatives), narcotic painkillers, or other medicines
  • Avoid consuming alcohol while taking the medicine as it can affect the working of the medicine.

Fact Box

Chemical Class
Phenanthrenes derivatives
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Opioid Antagonist

Patient concerns

arrow
Ferrous sulphate tablets toxicity
Dr. Megha Tuli
Obstetrics and Gynaecology
There is no toxicity as such. Please be specific in what respect are you asking.
Diazepam toxicity about 45 tablets
Dr. Ambrish Dharmadhikari
Psychiatry
Rush immediately to emergency services
arrow

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Yaksh TL, WallaceIn MS. Opioids, Analgesia, and Pain Management. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 512.
  2. Schumacher MA, Basbaum AI, Way WL. Opioids Analgesics & Antagonists. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 547-48.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 952-53.
  4. Naloxone hydrochloride dihydrate. King William Street, London: Advanz Pharma; 1990 [revised 30 Aug. 2012]. [Accessed 6 Apr. 2019] (online) Available from:External Link
  5. Medscape. Naloxone. [Accessed 6 Apr. 2019] (online) Available from:External Link
  6. Drugs.com. Naloxone injection. [Accessed 06 Apr. 2019] (online) Available from:External Link
  7. Naloxone. Richmond: Kaleo, Inc.; 1971 [revised Apr. 2014]. [Accessed 6 Apr. 2019] (online) Available from:External Link
  8. Central Drugs Standard Control Organisation (CDSCO). [Accessed 6 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Samarth Life Sciences Pvt Ltd
Address: Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Country of origin: India

NOT FOR SALE
We do not facilitate sale of this product at present

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