Navelbine 50mg Injection
Prescription Required
Product introduction
Navelbine 50mg Injection is an anti-cancer medication used in the treatment of breast cancer and non-small cell lung cancer.
It is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, weakness, fatigue, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. Men are advised to seek guidance and counselling on sperm conservation before taking this therapy.
It is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, weakness, fatigue, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. Men are advised to seek guidance and counselling on sperm conservation before taking this therapy.
Uses of Navelbine Injection
Benefits of Navelbine Injection
In Breast cancer
Navelbine 50mg Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Navelbine 50mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.
In Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Navelbine 50mg Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Side effects of Navelbine Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Navelbine
- Nausea
- Vomiting
- Weakness
- Fatigue
- Hair loss
- Low blood platelets
- Increased liver enzymes
- Fever
- Anemia (low number of red blood cells)
- Bleeding
- Constipation
How to use Navelbine Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Navelbine Injection works
Navelbine 50mg Injection blocks replication of genetic material (DNA) in the cancer cells. Thus it stops the growth and multiplication of cancer cells.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Navelbine 50mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Navelbine 50mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Navelbine 50mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
SAFE
Navelbine 50mg Injection does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Navelbine 50mg Injection is safe to use in patients with kidney disease. No dose adjustment of Navelbine 50mg Injection is recommended.
However, talk to your doctor if you have any underlying kidney disease.
However, talk to your doctor if you have any underlying kidney disease.
Liver
CAUTION
Navelbine 50mg Injection should be used with caution in patients with liver disease. Dose adjustment of Navelbine 50mg Injection may be needed. Please consult your doctor.
Regular monitoring of liver function tests is advised while these patients are taking this medicine.
Regular monitoring of liver function tests is advised while these patients are taking this medicine.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Navelbine 50mg Injection
₹16380/Injection
Neoben 50mg Injection
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Vinbicel 50 Injection
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Vinrel 50mg Injection
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Relbovin 50 Injection
Miracalus Pharma Pvt Ltd
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Vinelbine 50mg Injection
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₹12806.65/injection
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Quick tips
- Navelbine 50mg Injection is given as an injection into the vein under the supervision of a doctor.
- Do not skip any dose and complete the course as suggested by your doctor.
- Use an effective method of birth control to avoid pregnancy while taking this medication.
- Your doctor may get regular blood tests done to monitor your blood cell count, platelet count and liver function.
- Inform your doctor if you experience skin rash, swelling of face or lips and trouble breathing.
Fact Box
Chemical Class
Vinca alkaloids
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Antimicrotubule agents- Vinka alkaloid
Interaction with drugs
Taking Navelbine with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Vinorelbine from 14 days before until 24 days after taking Pegfilgrast
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Vinorelbine from 1 day before until 1 day after taking Sargramostim. P
Concomitant use may cause a reduction in white blood cell levels.
Do not consume Gefitinib with Vinorelbine.
Do not consume Vinorelbine with Erlotinib.
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytot
Patient concerns
User feedback
What are you using Navelbine Injection for?
Breast cancer
67%
Non-small cel*
33%
*Non-small cell lung cancer
How much was the improvement?
Excellent
67%
Average
33%
What were the side-effects while using Navelbine 50mg Injection?
Nausea
100%
How do you take Navelbine Injection?
With or witho*
100%
*With or without food
FAQs
Is Navelbine 50mg Injection a vesicant?
Yes, Navelbine 50mg Injection is a vesicant.
Is Navelbine 50mg Injection effective?
Navelbine 50mg Injection is effective for the dose and duration prescribed by the doctor for your condition.
How is Navelbine 50mg Injection administered?
Navelbine 50mg Injection is administered as an intravenous infusion.
Does Navelbine 50mg Injection cause hair loss?
Navelbine 50mg Injection has hair loss as a side effect. Please inform your doctor about any side effects that you may observe while on therapy.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1707.
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 949.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1479-80.
- Vinorelbine tartrate. Wedel, Germany: Medac GmbH; 2006 [revised Aug. 2017]. [Accessed 23 Jan. 2019] (online) Available from:
- Drugs.com. Vinorelbine Pregnancy and Breastfeeding Warnings. [Accessed 27 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Vinorelbine. [Updated 2018 Dec 3]. [Accessed 19 Feb. 2020] (online) Available from:
Marketer details
Name: Abbott
Address: 16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Country of origin: India
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