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Last updated
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Neganem 125mg Injection

Prescription Required
SALT COMPOSITION
Storage
Store below 30°C

Product introduction

Neganem 125mg Injection is an antibiotic that is used to treat severe infections of the skin, lungs, stomach, urinary tract, blood, and brain (eg. meningitis). It works by killing the bacteria that cause these problems. However, it will not treat a viral infection.

Neganem 125mg Injection is commonly used to treat critically ill patients admitted to the hospital. This medicine is given by drip/infusion or by direct injection into a vein, under the supervision of a doctor or a nurse. The dose will depend on what type of infection you have, where it is in the body, and how serious it is. You should keep on taking the injection for as long as you have been prescribed, even if your symptoms quickly improve. If you stop taking it too early the infection may return or worsen.

Some people may develop side effects like headache, nausea, constipation, diarrhea, anemia, vomiting, and rash. These side effects are usually temporary and go away as your body adjusts to the medicine. Consult your doctor if these side effects bother you or do not go away.

Before starting treatment with this medicine, you should tell your doctor if you have epilepsy (seizures), liver or kidney problems or if you are allergic to any antibiotic. While using it, you may be advised blood tests to monitor your blood cell count and kidney function. This medicine is generally regarded as safe to use in pregnancy and breastfeeding if prescribed by the doctor.

Uses of Neganem Injection

  • Severe bacterial infections

Benefits of Neganem Injection

In Severe bacterial infections

Neganem 125mg Injection belongs to a group of medicines called carbapenem antibiotics. It works by killing bacteria which can cause serious infections. It is a versatile medicine used to treat many different types of bacterial infections such as infections of the brain (meningitis), lungs (pneumonia), abdomen, urinary tract, skin, blood, and heart. This medicine is usually given as an injection by a doctor or nurse.

Neganem 125mg Injection usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Neganem Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Neganem

  • Rash
  • Headache
  • Vomiting
  • Nausea
  • Itching
  • Diarrhea
  • Injection site inflammation
  • Anemia (low number of red blood cells)
  • Sepsis
  • Constipation
  • Apnea (absence of breathing)
  • Shock

How to use Neganem Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Neganem Injection works

Neganem 125mg Injection is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.

Safety advice

Alcohol
SAFE
Consuming alcohol with Neganem 125mg Injection does not cause any harmful side effects.
Pregnancy
SAFE IF PRESCRIBED
Neganem 125mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Neganem 125mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Neganem 125mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Neganem 125mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Neganem 125mg Injection may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Neganem 125mg Injection is safe to use in patients with liver disease. No dose adjustment of Neganem 125mg Injection is recommended.

What if you forget to take Neganem Injection?

If you miss a dose of Neganem 125mg Injection, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Neganem 125mg Injection
₹196/Injection
Merosure 125mg Kit
Alkem Laboratories Ltd
₹269.24/injection
33% costlier
₹244.56/injection
21% costlier
Merotec 125mg Injection
Zuventus Healthcare Ltd
₹231.9/injection
15% costlier
₹149/injection
26% cheaper
Merosure 125mg Injection
Alkem Laboratories Ltd
₹145/injection
28% cheaper

Quick tips

  • Neganem 125mg Injection is an antibiotic that's usually only given in the hospital for serious infections.
  • Inform your doctor if you are allergic to penicillin or if you are taking any seizure medication before starting treatment with this medication.
  • Diarrhea may occur as a side effect. Inform your doctor if you develop severe stomach pain or if you find blood in your stools.
  • Your doctor may monitor your kidney function and blood count while you are having treatment with this medication.

Fact Box

Chemical Class
Carbapenem derivative
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Cell wall active agent -Carbapenems

Patient concerns

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Scar on face due to bacterial infections
Dr. Atul Jain
Dermatology
Pic is not clear, plz visit for proper opinion
I have a history of recurring yeast and bacterial vaginosis infections.
Dr. Sonu Balhara Ahlawat
Obstetrics and Gynaecology
Tab metrogyl 500 mg twice a day x 5 days and tab fluconazole 150 mg three doses alternate days
arrow

FAQs

Q. My friend has a history of epilepsy and she was on valproic acid while receiving treatment with Neganem 125mg Injection, still, she had an episode of seizure. Why?

Any previous history with any other medication should be informed to the doctor before starting your treatment with Neganem 125mg Injection. Medicines like Neganem 125mg Injection can interfere with valproic acid which is used for the treatment of epilepsy, making it less effective. So, the reason for the recent episode of seizure could be the result of such drug interaction. Generally, in cases like these, the doctor prescribes a different medicine.

Q. Even though Neganem 125mg Injection is used for skin infections, can it cause any skin-related problems?

Serious skin reactions are rare, but some have been reported with the use of Neganem 125mg Injection. Therefore, before starting the treatment inform your doctor if you are allergic to any medicine or antibiotic. Serious skin reactions are a type of allergic reaction. But, if not properly managed then they can endanger life. So, if you notice any rash along with fever or peeling of the skin, discontinue the medication and inform your doctor.

Q. Is Neganem 125mg Injection a strong antibiotic? Which infections does it treat?

Neganem 125mg Injection is a broad-spectrum antibiotic which means it can treat a variety of bacterial infections. It is used to treat infections affecting the lungs (pneumonia) and complicated infections of the urinary tract, abdomen, and skin and soft tissue infections. Along with that, it is also helpful in treating bacterial infection of the membranes that surround the brain and spinal cord (meningitis) and infections that occur during or after delivery.

Q. Is Neganem 125mg Injection effective against bacteria only? Can it be used for any type of bacterial infection?

Yes, Neganem 125mg Injection is effective only against bacteria. It is not effective against virus or fungal infections. Neganem 125mg Injection is effective against some bacteria which include Staphylococcus aureus, Streptococcus pneumoniae, S. pyogenes, S. viridans group, etc. Therefore, its use against any other type of bacteria should be avoided.

Q. My cousin was receiving Neganem 125mg Injection for severe skin infection, but the medicine was stopped when she had a fit. Was the fit due to Neganem 125mg Injection?

There are reports which suggest the occurrence of seizures or fits with the use of Neganem 125mg Injection. However, fits are more likely to occur in patients with a history of seizures or a brain lesion (wound, ulcer, abscess or tumor) or patients having bacterial meningitis or compromised kidney function. Consult your doctor to understand the exact reason.

Q. For how long will I need to take Neganem 125mg Injection?

The length of the treatment will be decided by your doctor. The doctor will decide the dose depending on your general health, the type of infection you have, and how well you respond to Neganem 125mg Injection. Consult your doctor if you are not sure.

Q. What if Neganem 125mg Injection does not suit me?

It is common to have minor side effects such as nausea, vomiting, diarrhea, and headache with the use of Neganem 125mg Injection. However, these symptoms generally settle down with continued medication as the body adapts to the medicine. If the side effects bother you, inform your doctor. The doctor will suggest an alternative medicine if required. Serious side effects with Neganem 125mg Injection are very rare. In case you develop serious side effects, seek immediate medical advice.

Q. Does it matter if I miss or stop Neganem 125mg Injection?

You mustn't stop the treatment without consulting your doctor. Stopping the treatment may bring back the infection or you may develop resistance to Neganem 125mg Injection. Similar results may be seen if you skip any dose or are forgetful in taking the suggested doses. Therefore, it is recommended that you do not miss doses. If you do, take the missed dose as soon as you can and take the next dose as planned so that you stick to the same overall daily dose.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Petri WA Jr. Penicillins, Cephalosporins, and Other β -Lactam Antibiotics. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1500.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 866-67.
  3. Meropenem. Wilmington, DE: AstraZeneca Pharmaceuticals; 1996 [revised Nov. 2013]. [Accessed 29 Mar. 2019] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:External Link
  5. Meropenem [Package Insert]. Vadodara, Gujarat: Samrudh Pharmaceuticals Pvt.Ltd.; 2021. [Accessed 11 Jul. 2023]. (online) Available from:External Link
  6. CiplaMed. Meropenem [Prescribing Information]. 03 Jun. 2021. [Accessed 11 Jul. 2023]. (online) Available from:External Link

Marketer details

Name: Venus Remedies Ltd
Address: SCO 857, Cabin No. 10, 2nd Floor, NAC, Manimajra, Chandigarh (U.T.), 160101, India
Country of origin: India

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We do not facilitate sale of this product at present

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