Neksium 40mg Injection
Prescription Required
Product introduction
Neksium 40mg Injection is a medicine that reduces the amount of acid produced in your stomach. It is used for treating acid-related diseases of the stomach and intestine such as acid reflux and some other stomach conditions associated with excessive acid production.
Neksium 40mg Injection is also used to prevent stress ulcers in seriously ill patients and is administered before anesthetic medication to help prevent aspiration-related complications. It belongs to a class of medicines known as proton pump inhibitors (PPIs). This medicine is administered into a vein by a healthcare professional and will only be given to you if your doctor thinks that an injection is more suitable for you at the moment than a tablet. The dose will depend on your underlying condition and how you respond to the medicine. Additionally, your doctor will decide the duration of treatment. You can increase the efficiency of the treatment by eating smaller meals more often and avoiding caffeinated drinks (like tea and coffee), and spicy or fatty foods.
The most common side effects observed with this medicine include injection site reactions, nausea, headache, dizziness, flatulence, diarrhea, stomach pain, and fundic gland polyps. These symptoms are generally mild but if they bother you or do not go away, consult your doctor. Talk to your doctor about ways to prevent bone loss (osteoporosis), like taking calcium and vitamin D supplements.
Neksium 40mg Injection is not suitable for some people. Before receiving this injection, you need to tell your doctor if you have severe liver problems, are taking medicines for HIV, have ever had an allergic reaction to similar medicines in the past, or suffer from bone loss (osteoporosis). Pregnant or breastfeeding women should also consult their doctor. Avoid drinking alcohol as it can make your stomach produce excessive acid and may worsen your symptoms.
Neksium 40mg Injection is also used to prevent stress ulcers in seriously ill patients and is administered before anesthetic medication to help prevent aspiration-related complications. It belongs to a class of medicines known as proton pump inhibitors (PPIs). This medicine is administered into a vein by a healthcare professional and will only be given to you if your doctor thinks that an injection is more suitable for you at the moment than a tablet. The dose will depend on your underlying condition and how you respond to the medicine. Additionally, your doctor will decide the duration of treatment. You can increase the efficiency of the treatment by eating smaller meals more often and avoiding caffeinated drinks (like tea and coffee), and spicy or fatty foods.
The most common side effects observed with this medicine include injection site reactions, nausea, headache, dizziness, flatulence, diarrhea, stomach pain, and fundic gland polyps. These symptoms are generally mild but if they bother you or do not go away, consult your doctor. Talk to your doctor about ways to prevent bone loss (osteoporosis), like taking calcium and vitamin D supplements.
Neksium 40mg Injection is not suitable for some people. Before receiving this injection, you need to tell your doctor if you have severe liver problems, are taking medicines for HIV, have ever had an allergic reaction to similar medicines in the past, or suffer from bone loss (osteoporosis). Pregnant or breastfeeding women should also consult their doctor. Avoid drinking alcohol as it can make your stomach produce excessive acid and may worsen your symptoms.
Uses of Neksium Injection
- Acidity
- Gastroesophageal reflux disease (Acid reflux)
- Peptic ulcer disease
Side effects of Neksium Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Neksium
- Injection site reaction
- Headache
- Dizziness
- Dryness in mouth
- Nausea
- Abdominal pain
- Constipation
- Flatulence
- Diarrhea
- Fundic gland polyps
How to use Neksium Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Neksium Injection works
Neksium 40mg Injection is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Neksium 40mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Neksium 40mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Neksium 40mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Neksium 40mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Neksium 40mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Neksium 40mg Injection may be needed. Please consult your doctor.
Dose adjustment is not required in patients with mild to moderate kidney disease.
Dose adjustment is not required in patients with mild to moderate kidney disease.
Liver
CAUTION
Neksium 40mg Injection should be used with caution in patients with severe liver disease. Dose adjustment of Neksium 40mg Injection may be needed. Please consult your doctor.
Dose adjustment is not required in patients with mild to moderate liver disease.
Dose adjustment is not required in patients with mild to moderate liver disease.
What if you forget to take Neksium Injection?
If you miss a dose of Neksium 40mg Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Neksium 40mg Injection
₹111/Injection
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Quick tips
- It is given as an injection into a vein under the supervision of the doctor.
- It is a well-tolerated medicine and provides relief for a long time.
- Some healthy tips to prevent acidity from happening:
- Avoid excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, caffeinated beverages like tea and coffee.
- Avoid alcohol and smoking.
- Avoid eating late at night or before bedtime.
- Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
- Long-term use of Neksium 40mg Injection can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
- Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.
- Neksium 40mg Injection should be taken 1 hour before a meal, preferably in the morning.
- It is a well-tolerated medicine and provides relief for a long time.
- Some healthy tips to prevent acidity from happening:
- Avoid excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, caffeinated beverages like tea and coffee.
- Avoid alcohol and smoking.
- Avoid eating late at night or before bedtime.
- Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
- Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
- Long-term use of Neksium 40mg Injection can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
- Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.
Fact Box
Chemical Class
Sulfinylbenzimidazole Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Proton-Pump Inhibitors
Interaction with drugs
Taking Neksium with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Esomeprazole may reduce blood levels of Erlotinib.
Do not consume Erlotinib with Esomeprazole.
Esomeprazole may cause low magnesium levels in the body and increase the risk of Digoxin poisoning.
Talk to your doctor if you notice any unusual symptoms.
Esomeprazole may raise blood levels of Cilostazol.
If concurrent use is essential, watch out for symptoms of Cilostazol side effects such as headache, palpitations, dizziness, swe
Esomeprazole may reduce the efficacy of Clopidogrel.
Do not consume Clopidogrel with Esomeprazole. If concurrent use is essential, watch out for bleeding and consult your doctor i
Patient concerns
FAQs
Is Neksium 40mg Injection safe to use?
Yes, Neksium 40mg Injection is relatively safe to use. Most of the people who take Neksium 40mg Injection do not get a side effect. It is advised to be taken as directed by the doctor for maximum benefit.
Can Neksium 40mg Injection cause weight gain?
Weight gain is reported in less than 1% of the patients taking Neksium 40mg Injection but the exact cause is unknown. One possible explanation is higher food intake once the reflux symptoms are relieved. Lifestyle modifications such as proper diet and exercise can help to prevent weight gain.
Can I take alcohol with Neksium 40mg Injection?
No, alcohol intake is not advised with Neksium 40mg Injection. Alcohol itself does not affect the working of Neksium 40mg Injection, but it can increase the acid production. This may further cause worsening of your symptoms
Can I take antacids along with Neksium 40mg Injection?
Yes, you can take antacids along with Neksium 40mg Injection. Take it 2 hours before or after you receive Neksium 40mg Injection.
What dietary changes should I make to get relief from acidity?
Neksium 40mg Injection is best taken 1 hour before a meal. You should avoid spicy and fatty foods while taking this medicine. You must refrain from caffeinated drinks such as tea, coffee, and cola. Alcohol intake should also be avoided as it may worsen your symptoms.
Are painkillers safe to take along with Neksium 40mg Injection?
Yes, it is safe to take painkillers along with Neksium 40mg Injection. Neksium 40mg Injection prevents acidity and stomach ulcers associated with the intake of painkillers. Neksium 40mg Injection is taken 1 hour before a meal. On the other hand, painkillers are usually taken with, or after a meal to avoid stomach upset.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Wallace JL, Sharkey KA. Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: The McGraw-Hill Companies, Inc.; 2011. [Accessed 24 Jan. 2019] (online) Available from:
- Esomeprazole sodium [FDA Label]. Wilmington, DE: AstraZeneca LP; 2012. [Accessed 24 Apr. 2020] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Esomeprazole. [Updated 2019 Jun 3]. [Accessed 20 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
- CiplaMed. Esomeprazole sodium [Prescribing Information]. [Last Revised: 12/03/2020]. [Accessed 22 Jun. 2023] (online) Available from:
- Esomeprazole sodium [Prescribing Information]. Wilmington, DE: AstraZeneca; 2022. [Accessed 22 Jun. 2023] (online) Available from:
Marketer details
Name: Pfizer Ltd
Address: The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.
Country of origin: India
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