Nexafen-E 500mg/250mg Tablet is a combination medicine used in the treatment of heavy menstrual bleeding. It works by preventing the breakdown of blood clots and controls excessive bleeding. It also increases the ability of platelets to stick together and form blood clots.

You can take Nexafen-E 500mg/250mg Tablet at any time of day, with or without food, but it is best to take it at the same time each day. Keep taking it for as long as advised by your doctor. Take this medicine in the dose and duration advised by the doctor and if you have missed a dose, take it as soon as you remember. Remember to finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor.

The most common side effects of this medicine include nausea, stomach pain, headache, nasal congestion, sinus pain, sinus inflammation, rash, tiredness, and musculoskeletal (bone, muscle or joint) pain. It may also cause diarrhea, so it is better to take plenty of fluids while taking this medicine as it may help to prevent dehydration. It is advised to consult with your doctor if you do not notice any changes in periods after 3 consecutive periods.

Before taking it, let your doctor know if you have any kidney problems or vaginal bleeding disorder. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking. You might be asked for eye check-ups while taking this medicine.

Uses of Nexafen-E Tablet

Heavy menstrual bleeding

Benefits of Nexafen-E Tablet

In Heavy menstrual bleeding

Nexafen-E 500mg/250mg Tablet helps normal blood clotting, which reduces the bleeding during menstruation. It helps to prevent excessive loss of blood, stops bleeding and enhances the healing process. This helps prevent complications of excessive bleeding such as hemorrhage. If heavy periods become such a problem that they interfere with your everyday life, then try taking things a little easier on those days. Some women find that relaxation techniques or yoga help them feel more relaxed and reduce stress. Getting a lot of exercise can also help.

Side effects of Nexafen-E Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nexafen-E

Nausea
Stomach pain
Diarrhea
Headache
Nasal congestion (stuffy nose)
Sinus pain
Sinus inflammation
Rash
Tiredness
Musculoskeletal (bone, muscle or joint) pain
Anemia (low number of red blood cells)

How to use Nexafen-E Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nexafen-E 500mg/250mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Nexafen-E Tablet works

Nexafen-E 500mg/250mg Tablet is a combination of two medicines: Tranexamic Acid and Ethamsylate. Tranexamic Acid is an antifibrinolytic. It works by preventing the breakdown of blood clots and controls excessive bleeding. Ethamsylate is a hemostatic. It works by increasing the ability of platelets to stick together and form blood clots. It also helps control bleeding from tiny blood vessels (capillaries).

Safety advice

Alcohol

UNSAFE

Nexafen-E 500mg/250mg Tablet may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Nexafen-E 500mg/250mg Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Nexafen-E 500mg/250mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

SAFE

Nexafen-E 500mg/250mg Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Nexafen-E 500mg/250mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Nexafen-E 500mg/250mg Tablet may be needed. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Nexafen-E 500mg/250mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Nexafen-E 500mg/250mg Tablet may not be needed in these patients. Please consult your doctor.

What if you forget to take Nexafen-E Tablet?

If you miss a dose of Nexafen-E 500mg/250mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Nexafen-E 500mg/250mg Tablet

₹16.8/Tablet

Sylate T 500mg/250mg Tablet

Emcure Pharmaceuticals Ltd

₹49.2/tablet

193% costlier

Tranlok E 500mg/250mg Tablet

Aristo Pharmaceuticals Pvt Ltd

₹26.1/tablet

55% costlier

Ethasyl T 500 mg/250 mg Tablet

FDC Ltd

₹24.2/tablet

44% costlier

K-Stat-ET Tablet

Mercury Laboratories Ltd

₹28.7/tablet

71% costlier

Trenamic E 500mg/250mg Tablet

Theon Pharmaceuticals Ltd.

₹21.7/tablet

29% costlier

View all substitutes

Quick tips

Nexafen-E 500mg/250mg Tablet is prescribed to reduce excessive bleeding during menstruation.
Stick to simple meals and avoid spicy rich food in order to avoid feeling sick (nausea).
If you get diarrhea while taking this medicine, consult your doctor immediately.
Along with taking Nexafen-E 500mg/250mg Tablet you can use a heating pad or try gentle massage and relaxation techniques to get relief during periods.
Inform your doctor if there is no improvement in your bleeding after using this medicine for three consecutive periods.
Inform your doctor if you have any bleeding disorders.

Fact Box

Habit Forming

Therapeutic Class

BLOOD RELATED

Patient concerns

Suddenly heavy menstrual bleeding

Dr. Megha Tuli

Obstetrics and Gynaecology

Tablet tranexa 500mg thrice a fay

Dear doctor my wife is 4 month pregnant since afternoon she is suffering from head ache , can you please suggest me what should be done

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

Tablet Crocin pain relief can. E given

I want to know about copper t is it safe to use for upto 2 years and does it have any side effects, is it possible copper t could be broken themselves

Dr. Jyoti Arora

Sexology

Copper-T is safe as a method of contraception but in some cases it causes heavy bleeding during menstrual cycle.If you have pain in the lower abdomen and heavy bleeding during your cycles then you should get yourself checked by a gynaecologist

Problem in eraction premature e

Dr. Pranay Gandhi

Sexology

hi PATIENT ejaculation: 1. medical treatment: Tablet tadapox or dejac-T 1 tablet 1 hour before sex 2. sex therapy: when u think u r about to come, just stop moving and ask ur partner to stop moving as well and stay still for 30 seconds. In 70%, these technique works. Other technique is to ask the partner to squeeze the glans penis with thumb and finger tightly just when u think u r about to come. This will prevent u from ejaculating.

FAQs

Can the use of Nexafen-E 500mg/250mg Tablet cause diarrhea?

Yes, the use of Nexafen-E 500mg/250mg Tablet can cause diarrhea. In case of diarrhea, drink plenty of water or other fluids. Talk to your doctor if diarrhea persists. Do not take any other medicine without consulting a doctor.

Can I use oral contraceptives while using Nexafen-E 500mg/250mg Tablet?

No, do not use oral contraceptives while using Nexafen-E 500mg/250mg Tablet. Use of oral contraceptives along with this medicine increases the chance of serious complications.

Will a higher than the recommended dose of Nexafen-E 500mg/250mg Tablet be more effective?

No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having serious side effects and toxicity. If the recommended doses do not relieve your symptoms or there is an increased severity of your symptoms, please consult your doctor.

What are the instructions for storage and disposal of Nexafen-E 500mg/250mg Tablet?

Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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References

Garay PR, Chiavaroli C, Hannaert P. Therapeutic Efficacy and Mechanism of Action of Ethamsylate, a Long-Standing Hemostatic Agent. Am J Ther. 2006;13(3):236-47. [Accessed 10 Apr. 2019] (online) Available from:
Medscape. Tranexamic acid. [Accessed 10 Apr. 2019] (online) Available from:
Negrete R, Molina M, Gutierrez-Aceves J. Preoperative administration of ethamsylate: reduces blood loss associated with percutaneous nepholithotomy? A prospective randomized study. J Urol. 2009;181(4S):625. [Accessed 10 Apr. 2019] (online) Available from:

Marketer details

Name: Iva Healthcare Pvt. Ltd.

Address: Iva Healthcare Private Limited, Manish Bansal(Director), Plot No. 400, Industrial Area, Phase 1, Panchkula - 134113, Haryana, India

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.