NI Plus Tablet is a combination medicine that helps in relieving pain. It is used to relieve pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It is also used to relieve fever, muscle pain, back pain, toothache, or pain in the ear and throat.
NI Plus Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.
The most common side effects of this medicine include nausea, vomiting, diarrhea, and increased liver enzymes. If any of these side effects bother you or get worse, you should speak to your doctor. Your doctor may be able to suggest ways of preventing or reducing the side effects.
Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.
Note: As per the Ministry of Health and Family Welfare, NI Plus Tablet is banned for children under 12 years of age.
NI Plus Tablet is a combination of two medicines that belong to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used for short term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Side effects of NI Plus Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of NI Plus
Nausea
Vomiting
Diarrhea
Increased liver enzymes
How to use NI Plus Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. NI Plus Tablet is to be taken with food.
How NI Plus Tablet works
NI Plus Tablet is a combination of two medicines: Nimesulide and Paracetamol. It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with NI Plus Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of NI Plus Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of NI Plus Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether NI Plus Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
NI Plus Tablet should be used with caution in patients with kidney disease. Dose adjustment of NI Plus Tablet may be needed. Please consult your doctor. Use of NI Plus Tablet is not recommended in patients with severe kidney disease.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of NI Plus Tablet in patients with liver disease. Please consult your doctor.
What if you forget to take NI Plus Tablet?
If you miss a dose of NI Plus Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
You have been prescribed this combination medicine for relieving pain and inflammation.
Take it with food to avoid getting an upset stomach.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness and increase the risk of liver damage.
Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough-and-cold) without asking your doctor first.
Fact Box
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Patient concerns
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NI Plus Tablet is a combination of two medicines: Nimesulide and Paracetamol. This medication helps in relieving the pain and inflammation. It works by lowering the levels of chemical substances in the body that cause pain and inflammation.
Can I stop taking NI Plus Tablet when my pain is relieved?
NI Plus Tablet is usually used for short-term pain relief and can be discontinued if there is no pain. However, it should be continued if your physician has advised you to do so.
Can the use of NI Plus Tablet cause nausea and vomiting?
Yes, the use of NI Plus Tablet can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medicine. In case of vomiting, drink plenty of water or other fluids by taking small and frequent sips. Talk to your doctor if vomiting persists and you notice any signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to your doctor.
Are there any specific contraindications associated with the use of NI Plus Tablet?
The use of NI Plus Tablet is considered to be harmful in patients with known allergy to any of the components or excipients of this medicine or in patients with known allergy to other painkillers (NSAIDs). Its use should also be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with the history of heart failure, high blood pressure, and liver or kidney disease.
Can I take NI Plus Tablet with Vitamin B-complex?
Yes, NI Plus Tablet can be taken with Vitamin B-complex preparations. While NI Plus Tablet helps to relieve pain, Vitamin B-complex helps to correct the vitamin deficiency that might be causing your symptoms.
Does NI Plus Tablet help in relieving stomach pain?
No, NI Plus Tablet preferably should not be taken for stomach pain without consulting a physician. This drug can increase stomach acid secretion which may aggravate an unknown underlying condition.
Can the use of NI Plus Tablet cause damage to the liver?
NI Plus Tablet contains Nimesulide and Paracetamol and both these medicines are known to cause harm to the liver especially in the doses above the recommended level. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with the underlying liver disease.
Is it safe to take a higher than the recommended dose of NI Plus Tablet?
No, you should avoid taking a higher than the recommended dose of NI Plus Tablet as it can increase the risks of side effects. If you are experiencing increased severity of pain or the pain is not relieved by the recommended doses, please consult your doctor for re-evaluation.
What are the recommended storage conditions for NI Plus Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
European Medicine Agency. Nimesulide; 2004. [Accessed 02 Apr. 2019] (online) Available from:
ScienceDirect. Nimesulide. [Accessed 02 Apr. 2019] (online) Available from:
ScienceDirect. Paracetamol. [Accessed 02 Apr. 2019] (online) Available from:
ScienceDirect. Nimesulide. [Accessed 02 Apr. 2019] (online) Available from:
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