Nicogem 10 Tablet is a medicine used to prevent and treat heart-related chest pain (angina). It is usually prescribed when other heart medicines are either not suitable or have not worked. It reduces the risk of an angina attack by widening blood vessels and improving blood flow to the heart.

Nicogem 10 Tablet may be taken with or without food. It should be swallowed whole with water. Take this medicine regularly and at about the same time(s) each day. Your doctor will decide the dose and how often you should take it. This may change from time to time depending on how well it is working. Do not stop taking it without talking to our doctor as sudden withdrawal may cause your chest pain to come back. You can improve the health of your heart by making some lifestyle changes such as quitting smoking, cutting down on alcohol, eating well, exercising regularly, and managing stress.

The most common side effect of this medicine is headache, especially during the first few days of treatment. This usually improves within a week. However, drinking plenty of fluids and avoiding alcohol may help. Other common side effects include dizziness or weakness, nausea, and flushing (sense of warmth in the face, ears, neck, and trunk). Talk to your doctor if these bother you or do not go away.

Nicogem 10 Tablet may not be suitable for some people. Inform your doctor if you have a history of low blood pressure or heart failure. Also let your doctor know about all other medications that you are using as some may affect, or be affected by this medicine. You should not take any medicines for erectile dysfunction with this medicine. Nicogem 10 Tablet is not usually recommended during pregnancy or breastfeeding.

Uses of Nicogem Tablet

Treatment of Angina (heart-related chest pain)

Benefits of Nicogem Tablet

In Treatment of Angina (heart-related chest pain)

Nicogem 10 Tablet helps in prevention as well as treatment of angina. Angina is a chest pain that is usually caused by the narrowing of the blood vessels which supply your heart. This means your heart does not get enough oxygen. Nicogem 10 Tablet relaxes and widens the blood vessels so more blood (and oxygen) gets to your heart. This reduces the pain and discomfort that angina causes thereby improving your ability to exercise and go about your daily life more easily. This medicine needs to be taken regularly to be effective so keep taking it even if you are not having any angina symptoms.

Side effects of Nicogem Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nicogem

Headache
Nausea
Vomiting
Weakness
Dizziness
Flushing (sense of warmth in the face, ears, neck and trunk)

How to use Nicogem Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nicogem 10 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Nicogem Tablet works

Nicogem 10 Tablet is a vasodilator. It works by reducing the workload of the heart. As a result, heart muscle does not need as much blood and oxygen supply. It also relaxes coronary artery (that carries blood to heart). This reduces the frequency and severity of angina attacks.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Nicogem 10 Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Nicogem 10 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Nicogem 10 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Nicogem 10 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Nicogem 10 Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nicogem 10 Tablet may not be needed in these patients. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Nicogem 10 Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Nicogem 10 Tablet may not be needed in these patients. Please consult your doctor.

What if you forget to take Nicogem Tablet?

If you miss a dose of Nicogem 10 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Nicogem 10 Tablet

₹10.7/Tablet

Nicoduce OD 10mg Tablet

Abbott

₹37.1/tablet

247% costlier

Nikos 10mg Tablet

Lloyd Healthcare Pvt Ltd

₹18.73/tablet

75% costlier

Nikoran 10 Tablet

Torrent Pharmaceuticals Ltd

₹31.45/tablet

194% costlier

K-Ion 10mg Tablet

Nouveau Medicament (P) Ltd.

₹8/tablet

25% cheaper

Korandil 10 Tablet

Sun Pharmaceutical Industries Ltd

₹28.8/tablet

169% costlier

View all substitutes

Quick tips

You must continue to take it as advised, usually for a long time.
Nicogem 10 Tablet may cause headaches. Drink plenty of water and take a suitable painkiller. Inform your doctor if it does not go away.
Nicogem 10 Tablet may cause dizziness or sleepiness. Do not drive or do anything which requires concentration until you know how it affects you.
Do not consume alcohol while taking Nicogem 10 Tablet as that may cause increased dizziness.
Do not take medications like sildenafil or tadalafil (prescribed for erectile dysfunction) while on treatment with Nicogem 10 Tablet as it may cause low blood pressure.
Inform your doctor if you notice any bleeding from the anal passage, blood in vomit or black stools.

Fact Box

Chemical Class

Nicotinamides Derivatives

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Potassium channel opener

Patient concerns

What is heart attack? When heart attack coming?

Dr. Nabajit Talukdar

Cardiology

Related to chest pain angina commonly

Chest pain headache vetrigo Angina pain

Dr. Nabajit Talukdar

Cardiology

Get echo n ECG done

FAQs

Q. What class of drug is Nicogem 10 Tablet and what is it used for?

Nicogem 10 Tablet belongs to a class of medicines known as “potassium channel openers”. It causes widening of the arteries. This decreases the workload of the heart to pump the blood. It also improves the blood and oxygen supply to your heart muscle. It is prescribed to patients with stable angina (heart-related chest pain) who cannot take other medicines (beta-blockers, calcium channel antagonist) meant for angina.

Q. Can I stop taking Nicogem 10 Tablet?

No, you should not stop taking Nicogem 10 Tablet without speaking to your doctor first. If you stop Nicogem 10 Tablet suddenly, your anginal pain may recur. Talk to your doctor if you are experiencing any side effects.

Q. How long does it take Nicogem 10 Tablet to start working?

Nicogem 10 Tablet starts working after about an hour of taking the medicine, but full benefits may be seen only after 4 to 5 days.

Q. For how long do I need to continue Nicogem 10 Tablet?

Continue taking your medicine for as long as your doctor tells you. Nicogem 10 Tablet is generally prescribed for a long term. You may even need to take it for the rest of your life.

Q. What if somebody accidentally takes excess of Nicogem 10 Tablet?

He or she should be taken to the hospital immediately. The person may experience signs of low blood pressure, which include feeling weak or dizzy. He or she may also experience irregular or fast heart beat.

Q. Can I take Nicogem 10 Tablet if I am taking aspirin?

You should avoid taking Nicogem 10 Tablet and aspirin together. Taking the two medicines together increases the risk of ulcer or bleeding in the mouth, stomach or intestine. Immediately consult your doctor, If you notice blood in your stool or vomit while using Nicogem 10 Tablet.

Q. Who should not use Nicogem 10 Tablet?

People who are allergic to Nicogem 10 Tablet or any of its ingredients should avoid using this medicine. Also, patients who have heart problems such as cardiogenic shock or left ventricular failure with low filling pressure or cardiac decompensation or have a build-up of fluid in the lungs (pulmonary edema) should not use Nicogem 10 Tablet. Additionally, patients taking medicines to treat erectile dysfunction (e.g., sildenafil, tadalafil, and vardenafil) or medicines to treat pulmonary hypertension (e.g., riociguat) should not use the medication. Your blood pressure may be affected if these medicines are taken with Nicogem 10 Tablet or if you have low blood volume.

Q. Can Nicogem 10 Tablet affect my sex life?

No, Nicogem 10 Tablet does not affect your sex life. However, it is not recommended to take medicines used to treat erectile dysfunction (e.g., sildenafil or tadalafil) or premature ejaculation (e.g., vardenafil or dapoxetine) while taking Nicogem 10 Tablet. Taking them together can lead to a serious drop in your blood pressure.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Opie LH, Horowitz JD. Nitrates and Newer Antianginals β-Blocking Agents. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 57.
Katzung BG, Chatterjee K. Vasodilator & the Treatment of Angina Pectoris. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 198.
Nicorandil. Guildford, Surrey: SANOFI; 2009 [revised 16 Mar. 2018]. [Accessed 25 Jan. 2019] (online) Available from:
Nicorandil. Macquarie Park, New South Wales: Sanofi-Aventis Australia Pty Ltd.; 2017. [Accessed 18 Jun. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
National Health Service. Nicorandil; 2019. [Accessed 18 Jun. 2019] (online) Available from:
Nicorandil [patient Information Sheet]. Ahmedabad, Gujarat: Torrent Pharmaceuticals Ltd. [Accessed 25 Jul. 2023] (online) Available from:

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