Nifedip LA Cream is a combination of two medicines used in the treatment of anal fissures (tear in the lining of the anus). It relieves the pain, swelling, itching, and discomfort associated with the passing of stools in people who suffer from problems in the anal area.

Nifedip LA Cream relaxes the blood vessels in the anus thus helping in the healing of anal fissures. It should be used in the dose and duration as directed by your doctor. Do not stop using it suddenly without talking to your doctor, as it may lead to worsening of your condition.

Before applying this medicine clean and dry the affected area. Make sure to wash your hands thoroughly before and after applying this medicine. Avoid getting this medicine into your eyes, nose, or mouth. If accidental exposure occurs, wash your eyes with water and seek immediate medical attention.

This medicine is generally well tolerated with minimal or no side effects. However, slight anal irritation and swelling may occur as a side effect of this medicine. This is temporary and usually resolves on its own in some time. Please consult your doctor if it does not resolve or persists for a longer duration. Inform your doctor immediately if you notice worsening of the infection or if you develop increased redness and irritation.

Uses of Nifedip Rectal Cream

Treatment of Anal fissure

Benefits of Nifedip Rectal Cream

In Treatment of Anal fissure

Nifedip LA Cream is used to relieve pain, irritation, or itching caused by anal fissures (tear in the lining of the anus). It relaxes the blood vessels thereby decreasing the pressure in the anal tissues. Use it in the dose and duration as advised by your doctor.

Side effects of Nifedip Rectal Cream

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nifedip

Anal irritation
Swelling

How to use Nifedip Rectal Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor.

How Nifedip Rectal Cream works

Nifedip LA Cream is a combination of two medicines: Lidocaine and Nifedipine. Lidocaine is a local anesthetic. It works by blocking pain signals from the nerves to brain which decreases pain sensation. Nifedipine is a calcium channel blocker (CCB). It works in anal fissure by blocking the action of calcium on blood vessels of anus.

Safety advice

Alcohol

No interaction found/established

Pregnancy

CONSULT YOUR DOCTOR

Nifedip LA Cream may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Nifedip LA Cream is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

No interaction found/established

Kidney

CAUTION

Nifedip LA Cream should be used with caution in patients with severe kidney disease. Dose adjustment of Nifedip LA Cream may be needed. Please consult your doctor.

Liver

CAUTION

Nifedip LA Cream should be used with caution in patients with liver disease. Dose adjustment of Nifedip LA Cream may be needed. Please consult your doctor.

What if you forget to take Nifedip Rectal Cream?

If you miss a dose of Nifedip LA Cream, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Nifedip LA Cream

₹103/Rectal Cream

Nifecaine Cream

Troikaa Pharmaceuticals Ltd

₹180/rectal cream

73% costlier

Escot Cream

DWD Pharmaceuticals Ltd

₹176/rectal cream

69% costlier

Anobliss Cream

Samarth Life Sciences Pvt Ltd

₹149.66/rectal cream

44% costlier

Anomed L Cream

Stadmed Pvt Ltd

₹181/rectal cream

74% costlier

Fidonal Cream

Abbott

₹330/rectal cream

217% costlier

Quick tips

It is for administration into the rectum (back passage). It must not be taken by mouth.
Use the applicator provided to insert a measured dose of cream into your back passage.
Avoid getting it in the eyes, mouth or nose. Rinse with cold water if you accidentally get it in these areas.
Tips to prevent constipation that can cause anal fissure:
- Drink plenty of fluids to stay hydrated.
- Have fiber-rich food such as whole grains, oatmeal, and citrus fruits.
- Exercise regularly.
- Do not sit on the toilet for too long.
- Do not ignore your urge to go to the washroom.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Patient concerns

I occasionally find blood in my stool.

Dr. Sfurti Mann

Internal Medicine

May be anal fissure, get yourself examined by a surgeon.

Fissure and fistula of anal region Fissure and fistula of anal and rectal region

Dr. Pushkar Mani

Physician

refer to surgeon again

User feedback

What are you using Nifedip Rectal Cream for?

Anal fissure

57%

Others

29%

Local anesthe*

14%

*Local anesthesia (Numb tissues in a specific area)

FAQs

Does Nifedip LA Cream cure anal fissures?

No, it does not cure fissures but Nifedip LA Cream reduces inflammation of mucous membrane and skin. It reduces irritation, alleviates pain and itching, thus providing symptomatic relief.

Why is my fissure not healing?

Fissures usually heal within a few weeks. But if they are not, this is because the oxygen supply, carried by the blood, to these fissures is poor which further slows down the healing process. As a result, these fissures fail to heal and continue to get worse. You should consult a doctor immediately if you have been facing issues for a duration longer than a few weeks.

What should I eat and avoid in fissure?

You must take a fiber-rich diet such as vegetables, fresh fruits and whole grains if you have fissures. Drink plenty of water and avoid taking alcohol. This will ensure that your stools are soft and easy to pass. You may also take laxatives or fiber supplements if you are facing issues with digestion. Your doctor will suggest ways to avoid constipation and thereby promote healing of fissures.

Can spicy food cause fissures?

No. Spicy foods do not cause fissures. But, they can irritate the fissures and worsen your symptoms. Therefore, it is advised that you avoid taking spicy foods if you are facing issues with your fissures.

How do you use Nifedip LA Cream cream?

Follow your doctor’s instructions before using Nifedip LA Cream. Apply a small amount of the ointment to the affected rectal area as directed. If this is to be used inside the rectum, attach the rectal applicator onto the tube. Insert the applicator gently and to full extent into the rectum. Gently squeeze the tube to deliver the medication while withdrawing it.

How long does it take to heal fissures?

Fissures usually heal within a few weeks. But, if they persist for longer than 4 to 6 weeks, they are termed as chronic fissures. Please consult your doctor without any delay if you have been noticing fissures for longer than 4 weeks.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Perrotti P, Dominici P, Grossi E, et al. Pharmacokinetics of Anorectal Nifedipine and Lidocaine (Lignocaine) Ointment Following Haemorrhoidectomy: An Open-Label, Single-Dose, Phase IV Clinical Study. Clin Drug Investig. 2009;29(4):243-56. [Accessed 17 Feb. 2020] (online) Available from:
Perrotti P, Dominici P, Grossi E, et al. Topical nifedipine with lidocaine ointment versus active control for pain after hemorrhoidectomy: results of a multicentre, prospective, randomized, double-blind study. Can J Surg. 2010;53(1):17-24. [Accessed 17 Feb. 2020] (online) Available from:
Bayview Pharmacy. Lidocaine and Nifedipine [Product Information]. [Accessed 16 Sep. 2024] (online) Available from:

Marketer details

Name: Delvin Formulations Pvt Ltd

Address: New No:25, 12th Cross Street, Shastri Nagar, Adyar, Chennai - 600020

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.