Nile SP 100mg/325mg/15mg Tablet is a combination medicine that helps in relieving pain. It works by blocking the release of certain chemical messengers that cause pain, inflammation, and fever in various conditions. It also promotes healing at the site of inflammation.
Nile SP 100mg/325mg/15mg Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.
The most common side effects of this medicine include nausea, vomiting, diarrhea, stomach pain, increased liver enzymes, and heartburn. If any of these side effects bother you or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the side effects.
Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.
Note: As per the Ministry of Health and Family Welfare, Nile SP 100mg/325mg/15mg Tablet is banned for children under 12 years of age.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nile SP
Nausea
Vomiting
Diarrhea
Stomach pain
Increased liver enzymes
Heartburn
How to use Nile SP Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nile SP 100mg/325mg/15mg Tablet is to be taken with food.
How Nile SP Tablet works
Nile SP 100mg/325mg/15mg Tablet is a combination of three medicines: Nimesulide, Paracetamol and Serratiopeptidase. Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) and Paracetamol is an antipyretic (fever reducer). They work by blocking the release of certain chemical messengers in the brain that cause pain and fever. Serratiopeptidase is an enzyme which works by breaking down abnormal proteins at the site of inflammation, and promotes healing.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Nile SP 100mg/325mg/15mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Nile SP 100mg/325mg/15mg Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Nile SP 100mg/325mg/15mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Nile SP 100mg/325mg/15mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Nile SP 100mg/325mg/15mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Nile SP 100mg/325mg/15mg Tablet may be needed. Please consult your doctor. Use of Nile SP 100mg/325mg/15mg Tablet is not recommended in patients with severe kidney disease.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Nile SP 100mg/325mg/15mg Tablet in patients with liver disease. Please consult your doctor.
What if you forget to take Nile SP Tablet?
If you miss a dose of Nile SP 100mg/325mg/15mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
You have been prescribed this combination medicine for relieving pain and inflammation.
Take it with food to avoid getting an upset stomach.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how Nile SP 100mg/325mg/15mg Tablet affects you.
Avoid consuming alcohol when taking Nile SP 100mg/325mg/15mg Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first.
You have been prescribed this combination medicine for relieving pain and inflammation.
Take it with food to avoid getting an upset stomach.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how Nile SP 100mg/325mg/15mg Tablet affects you.
Avoid consuming alcohol when taking Nile SP 100mg/325mg/15mg Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first.
Fact Box
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Patient concerns
One of my teeth is sensitive. It some times pains
Dr. Abhijit Gambhir
Dental Surgery
sensitivity has many causative factors for relief of pain you can take pain killers it will give temporary relief
I am suffering from chikungunya since last 2 days I m experiencing high fever and too much pain in my body Plzz suggest me about HOW TO NEUTRALIZE THE PAIN IN THE BODY
Can I stop taking Nile SP 100mg/325mg/15mg Tablet when my pain is relieved?
Nile SP 100mg/325mg/15mg Tablet is usually used for short-term pain relief and can be discontinued if there is no pain. However, it should be continued if advised by the doctor.
Can the use of Nile SP 100mg/325mg/15mg Tablet cause damage to the liver?
Nile SP 100mg/325mg/15mg Tablet contains nimesulide and paracetamol, and both these medicines are known to cause harm to the liver especially in doses above the recommended level. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with underlying liver disease.
Can I take a higher than the recommended dose of Nile SP 100mg/325mg/15mg Tablet?
No, taking a higher than the recommended dose of Nile SP 100mg/325mg/15mg Tablet can lead to increased chances of side effects. If the recommended dosage does not relieve your symptoms or you experience increased severity of pain, please consult your doctor for re-evaluation.
What are the instructions for the storage and disposal of Nile SP 100mg/325mg/15mg Tablet?
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
European Medicine Agency. Nimesulide; 2004. [Accessed 02 Apr. 2019] (online) Available from:
Bhagat S, Agarwal M, Roy V. Serratiopeptidase: A systematic review of the existing evidence. Int J Surg. 2013;11(3):209-17. [Accessed 02 Apr. 2019] (online) Available from:
ScienceDirect. Nimesulide. [Accessed 02 Apr. 2019] (online) Available from:
ScienceDirect. Paracetamol. [Accessed 02 Apr. 2019] (online) Available from:
PubChem. Serratiopeptidase. [Accessed 02 Apr. 2019] (online) Available from:
Marketer details
Name: Nordic Formulations Pvt Ltd
Address: D-59/105-B 57, Chandrika Nagar Colony, Sigra, Varanasi, India
Country of origin: India
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.