Nimodivine 30mg Tablet is a medicine used to treat and prevent further damage to the brain after bleeding around the brain (subarachnoid hemorrhage or SAH). It is known as a calcium channel blocker and helps to improve blood flow to the brain and prevent changes in brain function.

Nimodivine 30mg Tablet is usually started as soon as possible after bleeding around the brain (or SAH) is confirmed by the doctor. The exact dose and frequency will be decided by your doctor depending on your medical condition and response to treatment. It may be taken empty stomach or with a meal, but take it regularly as per your doctor’s instructions, to get the most benefit. Do not take any antacids for 2 hours before or after taking Nimodivine 30mg Tablet as this can prevent the medicine from working properly. Do not stop taking this medicine without first consulting your doctor. Your condition may worsen if this medicine is stopped too soon.

The most common side effects include decreased blood pressure, increased heart rate (tachycardia), headache, stomach discomfort, nausea, rash, muscle cramp, and edema (swelling over the whole body). Consult your doctor If any of these bother you, or get worse, or do not go away.

Before taking Nimodivine 30mg Tablet, let your doctor know if you have any heart or liver-related problems. Some other medicines may affect the way it works, especially some medicines used to treat seizures (fits) and those used to treat high blood pressure or heart conditions. Please tell your doctor about all the medicines you are taking to make sure you are safe. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. Your doctor will keep a watch on your blood pressure while you are taking this medicine.

Uses of Nimodivine Tablet

Side effects of Nimodivine Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nimodivine

Decreased blood pressure
Headache
Increased heart rate
Nausea
Rash
Stomach discomfort
Edema (swelling)
Muscle cramp

How to use Nimodivine Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nimodivine 30mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Nimodivine Tablet works

Nimodivine 30mg Tablet is a calcium channel blocker. It relaxes the narrow blood vessels in the brain and makes the blood flow more easily. This prevents brain damage after bleeding around the brain.

Safety advice

Alcohol

UNSAFE

Nimodivine 30mg Tablet may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Nimodivine 30mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Nimodivine 30mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Nimodivine 30mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Nimodivine 30mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nimodivine 30mg Tablet may not be needed in these patients. Please consult your doctor.

Liver

CAUTION

Nimodivine 30mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Nimodivine 30mg Tablet may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Nimodivine 30mg Tablet

₹21.6/Tablet

Nimodip Tablet

USV Ltd

₹25.3/tablet

17% costlier

Nimocer 30mg Tablet

Micro Labs Ltd

₹20.3/tablet

6% cheaper

Nimodec 30mg Tablet

United Biotech Pvt Ltd

₹9.49/tablet

56% cheaper

Vasotop 30mg Tablet

Cipla Ltd

₹5.82/tablet

73% cheaper

Nimpod 30mg Tablet

Intas Pharmaceuticals Ltd

₹8.81/tablet

59% cheaper

View all substitutes

Quick tips

Take it as per dose and duration suggested by your doctor.
Do not take any antacids for 2 hours before or after taking Nimodivine 30mg Tablet as it may affect the working of the medicine.
A sudden drop in your blood pressure may occur, especially when you first start taking Nimodivine 30mg Tablet. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Your doctor will monitor your blood pressure and heart rate during the treatment with this medicine.
Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding.
You have been prescribed Nimodivine 30mg Tablet to improve your blood pressure and/or to reduce the number and severity of angina attacks.
Lowering blood pressure reduces the chance of future heart attack and stroke.
Take it at the same time every day to help you remember to take it.
A sudden drop in your blood pressure may occur, especially when you first start taking Nimodivine 30mg Tablet. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
It can cause ankle or foot swelling. To reduce the swelling, raise your legs while you are sitting down. Talk to your doctor if it does not go away.
It may cause dizziness. Do not drive or perform any activity that requires mental focus until you know how Nimodivine 30mg Tablet affects you.
Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding.

Fact Box

Chemical Class

Dihydropyridinecarboxylic acids derivatives

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Calcium Channel Blockers- Dihydropyridines (DHP)

Interaction with drugs

Taking Nimodivine with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Primidone (Oral Route) Severe

Primidone may fasten removal of Nimodipine from the body. Primidone may reduce blood levels of Nimodipine. Do not consume Nimodipine with Primidone.

Phenobarbitone (Injection Route) Severe

Phenobarbitone may reduce blood levels of Nimodipine. Do not consume Nimodipine with Phenobarbitone.

Phenobarbitone (Oral Route) Severe

Phenobarbitone may reduce blood levels of Nimodipine. Do not consume Nimodipine with Phenobarbitone.

Estradiol (Oral Route) Moderate

Concurrent use may weaken the blood pressure-lowering effect of Nimodipine. Do not use Estradiol with Nimodipine, especially if you have heart disease. If concurrent use is essent... More

Imatinib mesylate (Oral Route) Moderate

Imatinib mesylate may raise blood levels of Nimodipine. watch out for symptoms such as nausea, decreased blood pressure, constipation or headaches and consult your doctor if you e... More

View all drug interactions

Patient concerns

What is heart attack? When heart attack coming?

Dr. Nabajit Talukdar

Cardiology

Related to chest pain angina commonly

Anal is pain it fissure or fistula Please anal is pain since 20 days

Dr. Ankur Kumar Tanwar

Ayurveda

Pain always occurs due to fissure

I am experiencing swelling and pain in anus. There is no bleeding. I need more time in latrine than normal. I am diabetic. I do mild jogging regularly for more than half an hour. I take around five glasses of water in empty stomach in the morning. I have no problem in passing daily stool other than the time consumed and now the pain is a problem while passing stool, walking and sitting.

Dr. Sunil Sekhri

Diabetology

Pain while passing stools could be due to anal fissure but to diagnose this condition a clinical check up is required

FAQs

How does Nimodivine 30mg Tablet work?

Nimodivine 30mg Tablet relaxes and widens the blood vessels so that blood can flow easily through them, thereby improving the blood supply to the brain. This as a result decreases brain damage due to internal bleeding in the brain and also prevents vasospasm (reflex narrowing of blood vessels caused by this bleeding).

What is Nimodivine 30mg Tablet?

Nimodivine 30mg Tablet belongs to a class of medicines known as calcium channel blockers. Nimodivine 30mg Tablet is used to prevent any further damage to the brain function which happens after subarachnoid haemorrhage (bleeding around the brain when a weak nerve in the brain bursts).

I am better now after taking Nimodivine 30mg Tablet. Can I stop taking it?

No, do not stop taking Nimodivine 30mg Tablet even if you start feeling better after taking it. This medicine is usually taken for 2 to 4 weeks. However, you must continue taking Nimodivine 30mg Tablet in the dose and duration advised by your doctor. If you stop taking it suddenly without consulting your doctor, your condition may worsen. Therefore, it is very important to follow your doctor’s instructions carefully and keep your doctor informed if you face any issues while taking Nimodivine 30mg Tablet.

What are the side effects of Nimodivine 30mg Tablet?

The most common side effects of Nimodivine 30mg Tablet are decreased blood pressure, headache, increased or decreased heart rate, nausea, rash, stomach discomfort, edema (swelling) and muscle cramps. These are usually not bothersome but you must consult your doctor if any of these worries you or gets worse.

What precautions do I need to take while taking Nimodivine 30mg Tablet?

Talk to your doctor if you ever had head injury or bleeding in and around the brain. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. If you have been taking this medicine through a drip, it is likely that you may be switched to a tablet form of Nimodivine 30mg Tablet to continue your treatment, once the drip is stopped. Inform your doctor if you have any problems with your heart, brain or liver. Do not take Nimodivine 30mg Tablet if you are allergic to it or any of its ingredients. Nimodivine 30mg Tablet should not be given to children below the age of 18 as the safety of Nimodivine 30mg Tablet is not known in children. Do not take antacids for 2 hours before or after taking Nimodivine 30mg Tablet as this may prevent the medication from working. Avoid taking alcohol while taking Nimodivine 30mg Tablet as it may only worsen the dizziness that may occur as a side effect of Nimodivine 30mg Tablet. You should not drive or do anything that requires focus as your alertness may be affected by Nimodivine 30mg Tablet. If you are pregnant, breastfeeding or planning to conceive, please consult your doctor before taking Nimodivine 30mg Tablet.

How do I give Nimodivine 30mg Tablet to a person who is unable to swallow properly?

If a person is unable to swallow properly, the doctor will suggest ways to give Nimodivine 30mg Tablet via a nasogastric tube. You must not mix the contents of Nimodivine 30mg Tablet into any other liquid or medicine as it may affect the working of the medicine. Nimodivine 30mg Tablet should not be injected. Follow your doctor’s instructions carefully to get maximum benefit.

What if I take an overdose of Nimodivine 30mg Tablet by mistake?

If you take an overdose of Nimodivine 30mg Tablet by mistake, get emergency medical help. Your blood pressure may decrease considerably and you may feel lightheaded or faint also. You may also experience irregular heart rate (fast or slow), making you feel sick or nauseated.

What if I forget to take a dose of Nimodivine 30mg Tablet?

If you miss a dose of Nimodivine 30mg Tablet, take it as soon as possible. Carry on taking that day’s dose at 4-hour intervals. Do not double the dose to make up for the missed one.

Can I take Nimodivine 30mg Tablet with food?

Nimodivine 30mg Tablet can be taken with or without food. Avoid eating grapefruit (chakotra) or drinking grapefruit juice while taking Nimodivine 30mg Tablet.

Is Nimodivine 30mg Tablet safe during pregnancy and breastfeeding?

No, Nimodivine 30mg Tablet is not safe if you are pregnant, planning to conceive or breastfeeding. Please consult your doctor before taking, as it may cause harmful effects to the baby.

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References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 980-82.
Nimodipine. Pointe-Claire, Canada: Importfab; 1988 [revised May 2013]. [Accessed 23 Jan. 2019] (online) Available from:
Nimodipine. Leverkusen, Germany: Bayer AG; 2017. [Accessed 20 Mar. 2019] (online) Available from:
Nimodipine. St. Petersburg, Florida: Cardinal Health; 2005. [Accessed 20 Mar. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 19 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:

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