Nishflam-XL Tablet is a pain relieving medicine. It is used to treat pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It may also be used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.

Nishflam-XL Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for longer duration than recommended by the doctor.

The most common side effects of this medicine include nausea, vomiting, heartburn, stomach pain, and indigestion. If any of these side effects do not resolve with time or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing them.

Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any problems with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking to make sure it is safe for you.

Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.

Uses of Nishflam-XL Tablet

Pain relief

Benefits of Nishflam-XL Tablet

In Pain relief

Nishflam-XL Tablet relieves pain, reduce swelling and ease inflammation in conditions like rheumatoid arthritis, osteoarthritis and ankylosing spondolytis. It also helps to manage short term symptoms such as muscle and back pain, toothache, or pain in the ear and throat if taken when the first sign of pain occurs. It works by reducing substances in the body that causes pain and swelling. Nishflam-XL Tablet also reduces fever associated with various painful conditions within 1-2 hour of taking a dose.

Side effects of Nishflam-XL Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nishflam-XL

Nausea
Vomiting
Heartburn
Stomach pain
Indigestion
Loss of appetite
Diarrhea

How to use Nishflam-XL Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nishflam-XL Tablet is to be taken with food.

How Nishflam-XL Tablet works

Nishflam-XL Tablet is a combination of three medicines: Aceclofenac, Paracetamol and Trypsin Chymotrypsin, which relieves pain. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) and Paracetamol is an antipyretic (fever reducer). They work by blocking the release of certain chemical messengers in the brain that cause pain and fever. Trypsin Chymotrypsin is a combination of enzymes which break down proteins into smaller fragments, thereby making them available for absorption into the blood. Once absorbed, they increase blood supply in the affected area and reduce swelling.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Nishflam-XL Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Nishflam-XL Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Nishflam-XL Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Nishflam-XL Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Nishflam-XL Tablet should be used with caution in patients with kidney disease. Dose adjustment of Nishflam-XL Tablet may be needed. Please consult your doctor.
Use of Nishflam-XL Tablet is not recommended in patients with severe kidney disease.

Liver

CAUTION

Nishflam-XL Tablet should be used with caution in patients with liver disease. Dose adjustment of Nishflam-XL Tablet may be needed. Please consult your doctor.
However, the use of Nishflam-XL Tablet is not recommended in patients with severe liver disease and active liver disease.

What if you forget to take Nishflam-XL Tablet?

If you miss a dose of Nishflam-XL Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Nishflam-XL Tablet

₹9.6/Tablet

Chymoral-AP Tablet

Torrent Pharmaceuticals Ltd

₹17.2/tablet

79% costlier

Chymocad Tablet

Cadila Pharmaceuticals Ltd

₹13.5/tablet

41% costlier

Chymonet AP Tablet

Leeford Healthcare Ltd

₹8.1/tablet

16% cheaper

Chymoking AP 100mg/325mg Tablet

Nusmith Pharma Pvt. Ltd

₹14.4/tablet

50% costlier

Anlof TC 100mg/325mg Tablet

Morecare Pharmatec Pvt Ltd

₹13.7/tablet

43% costlier

View all substitutes

Quick tips

You have been prescribed this combination medicine for relieving pain and inflammation.
Take it with food to avoid getting an upset stomach.
It may cause dizziness and sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking Nishflam-XL Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Patient concerns

I have SHT in last 10 years.I already take somany medicine but I can't get a good results.In my heart rate around 160 range.I feel chest tightness little pain also.I can't walk properly.Because that time I feel heavy palpitation and I hearing my heart beat sound in my ears.In my blood pressure shows on 170/100.Now I took these medicines.1 TRIOLMEZEST 40 Once daily morning.2 CALAPTIN-SR 120 once daily night.But still I not better now.Doctor said me after one month i need a Holter Monitoring test.I have no other physical problems.Please give me a feedback

Dr. Nabajit Talukdar

Cardiology

Add minipress xl 7.5 mg twice dailyHow is renal function test

Blakishbrown spots on both lower legs and feet about5 years no pain and swelling I have border line sugar taking cetanil m for bp pl suggest cause and treatment

Dr. Souvik Sardar

Dermatology

Use momate xl cream mixed with aquasoft cream in 1 : 1 ratio - apply twice daily for 4wks

Since long time I am taking Tab. Libotryp XL 25. Also taking Amlopin M 50 & LTK 50 bec I m BP Patient. Without taking Libotryp xl I can't sleep. I know it is dangerous for long period. Please guide me is there any option?

Dr. Venkatraju Kalidindi

Psychiatry

Dear 1mg user, medicines gives quick relief and has side effects too so consult your doctor and see how to reduce dose and control totally, later you can take counselling that really helps you. Pay Rs 99 and call me on my phone www.dontfeel.com for counselling. please try curd rice in dinner Curd Dhahi" "yogurt" has good qualities it acts as digestive and get good sleep."

FAQs

What is Nishflam-XL Tablet?

Nishflam-XL Tablet is a combination of four medicines: Aceclofenac, Paracetamol, Trypsin and Chymotrypsin. This medicine helps in decreasing pain and swelling. It lowers the levels of chemical substances in the body that causes pain and swelling.

Can I get addicted to Nishflam-XL Tablet?

No, there is no report of any patient getting addicted to Nishflam-XL Tablet.

Can I stop taking Nishflam-XL Tablet when my pain is relieved?

Nishflam-XL Tablet is usually used for short term and can be discontinued when your pain is relieved. However, Nishflam-XL Tablet should be continued if your doctor has advised you to do so.

Can the use of Nishflam-XL Tablet cause dizziness?

Yes, the use of Nishflam-XL Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better.

Can the use of Nishflam-XL Tablet cause damage to kidneys?

Yes, long-term use of Nishflam-XL Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protects them from damage. Use of painkillers lowers the levels of prostaglandins in the body leading to kidney damage due to long-term use. Use of painkillers is not recommended to patients with underlying kidney disease.

Can the use of Nishflam-XL Tablet cause damage to liver?

Nishflam-XL Tablet contains Paracetamol. This medicine is known to cause harm to the liver especially in the doses above the recommended level. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with underlying liver disease. Contact your doctor immediately if you notice any early signs and symptoms of liver damage. These symptoms may include fever, rash, loss of appetite, nausea, vomiting, fatigue, stomach pain, dark urine, yellow skin or eyes and abnormal liver enzymes.

How long will Nishflam-XL Tablet take to act?

It may take about an hour to see the initial benefit of pain relief after taking Nishflam-XL Tablet.

What if I forget to take Nishflam-XL Tablet?

If you forget to take the scheduled dose of Nishflam-XL Tablet and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effect. If you are not sure what to do, consult your doctor about how to manage a situation like this.

Will a higher than the recommended dose of Nishflam-XL Tablet be more effective?

No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms, that are not relieved by the recommended doses, please consult your doctor for re-evaluation.

Are there any specific contraindications associated with the use of Nishflam-XL Tablet?

The use of Nishflam-XL Tablet is considered to be harmful for patients with known allergy to any of the component or excipients of this medicine. The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer / bleeding. It should also be avoided in patients with history of heart failure, high blood pressure, and liver or kidney disease.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Shah D, Mital K. The Role of Trypsin: Chymotrypsin in Tissue Repair. Adv Ther. 2018;35(1):31-42. [Accessed 22 Apr. 2019] (online) Available from:
Trypsin-Chymotrypsin with Paracetamol and Aceclofenac Tablets [Patient Information Leaflet]. Ahmedabad, Gujarat: Torrent Pharmaceuticals; 2020. [Accessed 16 Sep. 2024] (online) Available from:

Marketer details

Name: Ronish Bioceuticals

Address: Ronish House, Nanhera Link Road, Kuldeep Nagar, Ambala Cantt

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.