Nixphylle 400mg Tablet SR is a pain relieving medicine. It is used to treat acute and chronic pain associated with various conditions such as muscle pain, headache, nerve pain, postoperative pain, and menstrual cramps. It is not recommended for use in patients less than 18 years of age.

Nixphylle 400mg Tablet SR can be taken with or without food. In general, you should try to use the smallest amount necessary to control your symptoms, for the shortest possible time. You should take this medicine regularly while you need it. Try not to miss doses as this will make the medicine less effective.

Some of the common side effects of this medicine include fatigue, dizziness, drowsiness, nausea, dryness in mouth, and abdominal bloating. If any of these side effects do not go away or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.

To make sure it is safe for you, before taking this medicine, let your doctor know if you have any medical conditions or disorders. You should also tell your doctor all the other medicines you are using or taking. Pregnant and breastfeeding women should consult their doctors before using this medicine.

Uses of Nixphylle Tablet SR

Pain relief

Benefits of Nixphylle Tablet SR

In Pain relief

Nixphylle 400mg Tablet SR helps relieve moderate to severe pain in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like muscle pain, headache, nerve pain, postoperative pain, and menstrual cramps. The dose and duration will be decided by the doctor depending on the condition you are being treated for. This medicine helps one go about their daily activities more easily and have a better, more active, quality of life.

Side effects of Nixphylle Tablet SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nixphylle

Fatigue
Dizziness
Nausea
Dryness in mouth
Tremors
Heartburn
Vomiting
Abdominal pain
Constipation
Loss of appetite
Depression
Headache
Abdominal discomfort
Sleep disturbance
Increased sweating
Restlessness
Nervousness
Flatulence
Diarrhea

How to use Nixphylle Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nixphylle 400mg Tablet SR may be taken with or without food, but it is better to take it at a fixed time.

How Nixphylle Tablet SR works

Nixphylle 400mg Tablet SR decreases the perception of pain by blocking the transmission of pain signals to the brain.

Safety advice

Alcohol

UNSAFE

Nixphylle 400mg Tablet SR may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Nixphylle 400mg Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Nixphylle 400mg Tablet SR during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Nixphylle 400mg Tablet SR alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CAUTION

Nixphylle 400mg Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Nixphylle 400mg Tablet SR may be needed. Please consult your doctor.

Liver

CAUTION

Nixphylle 400mg Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Nixphylle 400mg Tablet SR may be needed. Please consult your doctor.

What if you forget to take Nixphylle Tablet SR?

If you miss a dose of Nixphylle 400mg Tablet SR, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Nixphylle 400mg Tablet SR

₹29.1/Tablet SR

Ketoflam SR Tablet

Lupin Ltd

₹30.9/tablet sr

6% costlier

Lupirtin -SR Tablet

Lupin Ltd

₹32.5/tablet sr

12% costlier

Flugesic SR Tablet

Lupin Ltd

₹31.8/tablet sr

9% costlier

Fluprisan 400mg Tablet SR

Eisai Pharmaceuticals India Pvt Ltd

₹15.2/tablet sr

48% cheaper

Flunalgen SR 400 Tablet

Dyso Healthcare Pvt Ltd

₹15/tablet sr

48% cheaper

Quick tips

Nixphylle 400mg Tablet SR is given when pain killers (NSAIDs) cannot be given due to gastric damage caused by them.
Inform your doctor before starting Nixphylle 400mg Tablet SR if
- You have an underlying liver disease
- You take alcohol regularly
- You are pregnant or planning to get pregnant or breastfeeding
Get your liver function tests done before starting Nixphylle 400mg Tablet SR and follow up tests every week while you are taking the medicine.
Stop taking Nixphylle 400mg Tablet SR and immediately inform your doctor if you get any symptoms of liver disease like nausea, vomiting, stomach pain or yellow colored urine.

Fact Box

Chemical Class

Pyridine Derivative

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

Selective neuronal potassium channel openers (SNEPCO)

Patient concerns

One of my teeth is sensitive. It some times pains

Dr. Abhijit Gambhir

Dental Surgery

sensitivity has many causative factors for relief of pain you can take pain killers it will give temporary relief

fever and 2 months pregnant can take combiflan

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

No take Crocin for pain relief

FAQs

Is Nixphylle 400mg Tablet SR beneficial in the treatment of fibromyalgia?

Yes, Nixphylle 400mg Tablet SR is seen to be beneficial in the treatment of fibromyalgia in some clinical studies, however, Nixphylle 400mg Tablet SR is yet to get formal regulatory approval for this condition. Fibromyalgia is a disease that is characterized by musculoskeletal pain, fatigue, and depression.

What is the benefit of using Nixphylle 400mg Tablet SR with paracetamol?

Both Nixphylle 400mg Tablet SR and paracetamol help in relieving pain but they work in entirely different ways. When paracetamol is given with Nixphylle 400mg Tablet SR, pain relief is better as compared to single drug use. However, both can cause liver toxicity, so monitoring of liver function is very important when taken together.

Does Nixphylle 400mg Tablet SR cause liver toxicity?

Yes, Nixphylle 400mg Tablet SR causes liver toxicity. Use of Nixphylle 400mg Tablet SR is contraindicated in patients with an underlying liver disease.

Can Nixphylle 400mg Tablet SR be used for the treatment of osteoarthritis pain?

Nixphylle 400mg Tablet SR can be used for the relief of pain associated with osteorthritis and post orthopedic surgery pain. It is especially useful for patients who cannot take NSAIDs because of the risk of NSAID-induced gastritis.

Does use of Nixphylle 400mg Tablet SR cause green discoloration of urine?

There have been case reports that Nixphylle 400mg Tablet SR causes green discoloration of urine. However, this is not a very commonly seen effect. Inform your doctor if you experience this symptom.

Is Nixphylle 400mg Tablet SR useful in the treatment of epilpesy?

Nixphylle 400mg Tablet SR is not approved for the treatment of epilepsy. However, a few animal studies have shown a beneficial effect of Nixphylle 400mg Tablet SR for treating epilepsy and this effect is still being explored.

Would I experience any withdrawal symptoms once I stop using Nixphylle 400mg Tablet SR?

Yes, you can experience withdrawal symptoms once you stop using Nixphylle 400mg Tablet SR like sweating, tremor, and mood alterations with long term use of Nixphylle 400mg Tablet SR. Inform your doctor if you have these symptoms.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Sciencedirect. Flupirtine. [Accessed 02 Apr. 2019] (online) Available from:
Harish S, Bhuvana K, Bengalorkar GM, et al. Flupirtine: Clinical pharmacology. J Anaesthesiol Clin Pharmacol. 2012;28(2):172-7. [Accessed 24 Jan. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:

Marketer details

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Address: plot no. : 133/53-a, o-block, kidwai nagar - 208 011, kanpur – india

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.