Nobeglar UNO 100IU/ml Pre-filled Pen is a long-acting type of insulin used to treat types 1 and 2 diabetes mellitus in both adults and children. It provides a steady level of insulin in the body for an entire day and helps control blood sugar levels. This helps to prevent complications of diabetes.
Nobeglar UNO 100IU/ml Pre-filled Pen can be prescribed alone or in combination with fast-acting insulin or other diabetes medicines. Your doctor or nurse will teach you how to inject it under the skin correctly. You should use this medicine regularly per the dose advised to get the maximum benefit. If you stop taking it, your blood sugar levels may rise very high, which may put you at risk of serious complications. It is only a part of the treatment program that should include a healthy diet, regular exercise, and weight reduction, as your doctor advises.
This medicine's most common side effect is low blood sugar levels (hypoglycemia). To prevent this, it is important to inject only the correct dose of medicine, have regular meals, and monitor your blood sugar levels regularly. Drinking excessive alcohol can also lead to a fall in your blood sugar levels. Other common side effects include peripheral edema, lipodystrophy, allergic reactions, injection site reactions, itching, rashes, and weight gain.
Do not use this medicine when you have low blood sugar levels. Before starting the treatment, inform your doctor if you have ever had kidney, liver, or heart problems. Pregnant or breastfeeding women should consult their doctor before using it.
Nobeglar UNO 100IU/ml Pre-filled Pen is a man-made form of insulin that helps to control high blood glucose (sugar) levels. It replaces the insulin that is usually produced in the body. This allows the glucose into your cells so your body can use it for energy. Lowering blood sugar levels helps reduce the risk of getting any of the serious complications of diabetes, such as kidney damage, eye damage, nerve problems, and loss of limbs.
Side effects of Nobeglar UNO Pre-filled Pen
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nobeglar UNO
Edema (swelling)
Allergic reaction
Injection site reactions (pain, swelling, redness)
Lipodystrophy (skin thickening or pits at the injection site)
Itching
Rash
How to use Nobeglar UNO Pre-filled Pen
Your doctor or nurse will use this device to give medicine. You or your care giver may be taught on how to use this device at home.
How Nobeglar UNO Pre-filled Pen works
Nobeglar UNO 100IU/ml Pre-filled Pen is a long-acting insulin that provides consistent, all-day sugar control. It works like your body's natural insulin. Insulin facilitates the reuptake of sugar in muscle and fat cells and suppresses sugar production in the liver.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Nobeglar UNO 100IU/ml Pre-filled Pen.
Pregnancy
SAFE IF PRESCRIBED
Nobeglar UNO 100IU/ml Pre-filled Pen is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Nobeglar UNO 100IU/ml Pre-filled Pen is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Nobeglar UNO 100IU/ml Pre-filled Pen should be used with caution in patients with kidney disease. Dose adjustment of Nobeglar UNO 100IU/ml Pre-filled Pen may be needed. Please consult your doctor. Regular monitoring of blood glucose levels is recommended for dose adjustment.
Liver
CAUTION
Nobeglar UNO 100IU/ml Pre-filled Pen should be used with caution in patients with liver disease. Dose adjustment of Nobeglar UNO 100IU/ml Pre-filled Pen may be needed. Please consult your doctor. Regular monitoring of glucose levels is recommended for dose adjustment.
What if you forget to take Nobeglar UNO Pre-filled Pen?
If you miss a dose of Nobeglar UNO 100IU/ml Pre-filled Pen, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
Nobeglar UNO 100IU/ml Pre-filled Pen is injected under the skin. It needs to be injected once daily, at the same time every day.
Injection below the skin of the abdomen results in faster absorption than other injection sites.
Injection sites must be rotated to prevent hard lumps from developing at one site.
Exercise regularly, eat a healthy diet, and take your other diabetes medicines (if prescribed) alongside.
Hypoglycemia (low blood sugar level) is a common side effect. Hence, regular monitoring of blood sugar levels is required while taking this medicine.
Always carry some high-sugar food, such as sugar candy or glucose candy, fruit juice, and glucose, with you so that you can take it when you experience hypoglycemia symptoms such as cold sweats, cool, pale skin, tremors, weakness, and anxiety.
Opened vials/cartridges can be kept at room temperature for up to 4 weeks, while unopened vials must be stored in the refrigerator (2°C–8°C).
Do not use if the preparation is no longer clear and colorless or if it contains particles.
Fact Box
Chemical Class
Insulin analogue
Habit Forming
No
Therapeutic Class
ANTI DIABETIC
Action Class
Insulin analogues- long acting
Patient concerns
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Physician
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Physician
A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND LOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you souls not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET
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A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET
What kind of insulin is Nobeglar UNO 100IU/ml Pre-filled Pen?
Nobeglar UNO 100IU/ml Pre-filled Pen is a man-made insulin that is very similar to human insulin. It has a long and steady (constant) effect on blood sugar levels, lasting an entire day. This makes it suitable for use once daily. It treats type 2 diabetes mellitus in adults and type 1 diabetes mellitus in adults and children.
What should I know before using Nobeglar UNO 100IU/ml Pre-filled Pen?
Nobeglar UNO 100IU/ml Pre-filled Pen is injected under the skin (subcutaneously) with a pen-like device or an insulin syringe and needle. There are various areas on the body where insulin can be injected, such as the abdomen (stomach area), thighs (upper portion of legs), upper arms, hips, or buttocks. Your doctor will show you the area of your skin where you should inject it. Never inject it directly into a vein or a muscle. Before using Nobeglar UNO 100IU/ml Pre-filled Pen, make sure the solution is colorless and free of particles. It should strictly be taken in the dose that has been prescribed to you. Follow your doctor’s instructions on administering Nobeglar UNO 100IU/ml Pre-filled Pen correctly and monitor your blood sugar levels regularly.
How is Nobeglar UNO 100IU/ml Pre-filled Pen administered?
Nobeglar UNO 100IU/ml Pre-filled Pen is injected just below the skin (subcutaneously). Your doctor will train you on the correct method and the areas (abdomen or stomach, thighs, arms, hips, or buttocks) where you should inject it. It is advised that the injection site should be changed within the chosen skin area for every dose. For example, if you have been advised to inject it into the skin of your stomach, avoid puncturing the same point on your stomach every day. Instead, inject the needle at a site that is slightly away, say around 1cm, from the previous injection. You can also consider switching sides while injecting, like choosing the right side on one day and the left side on the next day. This way, you can reduce the complications associated with repeated injections in the same site, such as thickening of the fat tissue below the skin, known as lipodystrophy, irritation, pain, etc. After one to two weeks, you should move to another area of your body (e.g., from the stomach to the arms or thighs) as your doctor advises. Consult your doctor if you face any problems while injecting Nobeglar UNO 100IU/ml Pre-filled Pen.
Can I take Nobeglar UNO 100IU/ml Pre-filled Pen twice a day?
Nobeglar UNO 100IU/ml Pre-filled Pen is long-acting and usually prescribed to be taken once daily. It can be taken at any time, but try to take it at the same time each day.
What will happen if I accidentally inject more than the prescribed dose of Nobeglar UNO 100IU/ml Pre-filled Pen?
If you have accidentally taken more than the prescribed dose of Nobeglar UNO 100IU/ml Pre-filled Pen, your blood sugar levels may become too low (hypoglycemia). This hypoglycemia may be mild or severe. Monitor your blood sugar levels more frequently for the next 24 hours. Mild episodes of hypoglycemia (with symptoms like anxiety, sweating, weakness, tremors, and fast heartbeat) can usually be corrected with the help of sugary foods such as sugary candy, fruit juice, and glucose. However, it is important to consult your doctor to decide on a further course of treatment. More severe episodes of hypoglycemia may even lead to a seizure (fit) or unconsciousness. This can be life-threatening, and the patient should be rushed to an emergency.
How should Nobeglar UNO 100IU/ml Pre-filled Pen be stored?
Keep this medication out of the reach of children in the container it came in. Store unopened vials and pens in the refrigerator, but do not freeze them. An unopened Nobeglar UNO 100IU/ml Pre-filled Pen can be stored in the refrigerator until the date shown on the company's label. Moreover, never use Nobeglar UNO 100IU/ml Pre-filled Pen that has been frozen or defrosted. If a refrigerator is unavailable, the vials can be stored at room temperature and away from direct sunlight and extreme heat. It should appear as a clear, colorless solution free from particles.
In what circumstances will the dose of Nobeglar UNO 100IU/ml Pre-filled Pen need to be changed?
You should consult your doctor about the scenarios where you may need to adjust your insulin dose. For example, if you are ill, you should monitor your blood sugar levels more closely. You must tell your doctor about all the medicines you are taking because many medicines can affect how insulin acts, and you may need to modify your dose. Your eating habits may also affect your dose; for example, if you eat less someday, skip a meal, or eat more than usual. Your blood sugar level may alter depending on your exercise regime, alcohol consumption, or stress. Pregnant and breastfeeding mothers should consult their doctor before taking Nobeglar UNO 100IU/ml Pre-filled Pen as they may need to change their dose.
What are the serious side effects of Nobeglar UNO 100IU/ml Pre-filled Pen?
Serious side effects are rare with Nobeglar UNO 100IU/ml Pre-filled Pen. Sometimes, severe allergic reactions may be seen with it. This can lead to rash, hives, itching all over the body, trouble breathing (wheezing), fast heart rate, and low blood pressure. Get medical help right away if you develop any of these symptoms. Other side effects include severe hypoglycemia (low blood sugar levels), which can cause dizziness, sweating, anxiety, confusion, headache, blurred vision, slurred speech, shakiness, fast heartbeat, seizure (fit), and unconsciousness. Taking certain medicines such as TZDs (thiazolidinediones) may cause heart failure in some people, even if they have never had any heart problems before. Some people may also notice sudden weight gain and swelling (edema) of ankles or feet. Consult your doctor immediately if you notice any of these side effects.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1251-52.
Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 734.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 720.
Insulin glargine. Sesto Fiorentino, Italy: Eli Lilly Italia S.p.A.; 2018. [Accessed 12 Mar. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 12 Mar. 2019] (online) Available from:
Lantus [Summary of Product Characteristics]. Frankfurt am Main, Germany: Sanofi-Aventis Deutschland GmbH; 2015. [Accessed 08 Oct. 2021] (online) Available from:
Insulin Glargine [Product Monograph]. Toronto, Ontario: Eli Lilly, Canada Inc.; 2021. [Accessed 08 Oct. 2021] (online) Available from: