Nolvadex 20mg Tablet
Prescription Required
Product introduction
Nolvadex 20mg Tablet is an anti-estrogens. It is used in the treatment of breast cancer. It is also used to reduce the risk of breast cancer in pre- and postmenopausal women with a high risk. This medicine helps to slow down the growth and multiplication of cancer cells.
Nolvadex 20mg Tablet is also helpful in the treatment of infertility. It can be taken with or without food, but take it at the same time to get the most benefit. It should be taken as your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. Swallow the tablets whole with a drink of water. This medicine is generally taken for 10 to 15 years. You should take this medicine for as long as it is prescribed for you.
The most common side effects of this medicine include hot flashes, mood swings, vaginal bleeding, nausea, and fluid retention. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Some side effects may mean you should inform your doctor immediately include vaginal bleeding, irregular menstrual period, and vaginal discharge. It makes birth control pills less effective, hence use a condom and other preventive measures to avoid pregnancy.
Before taking this medicine, tell your doctor if you are on treatment of infertility or had a blood clot disorder. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant or breastfeeding. Your doctor may perform some blood tests to check liver function and calcium level in the body.
Uses of Nolvadex Tablet
Benefits of Nolvadex Tablet
In Breast cancer
Nolvadex 20mg Tablet relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipple or changes in the shape or texture of the breast. It works by altering the production of those hormones in the body that are essential for the growth and spread of breast cancer, both in pre as well as postmenopausal women. It may also interact with other hormones or have a direct effect on the cancer to stop its growth.
Side effects of Nolvadex Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nolvadex
- Vaginal discharge
- Mood swings
- Fatigue
- Nausea
- Skin rash
- Vaginal bleeding
- Constipation
- Fluid retention
- Hot flushes
- Hair loss
- Vomiting
- Diarrhea
- Fibroid
- Anemia (low number of red blood cells)
- Hypersensitivity
- Ischemic cerebrovascular events
- Headache
- Lightheadedness
- Sensory disturbance
- Cataract
- Retinopathy
- Thromboembolic events
- Abnormal liver enzyme
- Fatty liver disease
- Leg cramps
- Muscle pain
- Vaginal itching
- Endometrial changes
- Increased triglyceride level in blood
How to use Nolvadex Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nolvadex 20mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Nolvadex Tablet works
Nolvadex 20mg Tablet is a hormone-based medication. It works by binding to estrogen receptors and blocking the effects of estrogen (a natural female hormone) in the breast tissue. This slows down the growth and multiplication of breast cancer cells.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Nolvadex 20mg Tablet.
Pregnancy
UNSAFE
Nolvadex 20mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Nolvadex 20mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Nolvadex 20mg Tablet may cause side effects which could affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Nolvadex 20mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nolvadex 20mg Tablet may not be needed in these patients. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Nolvadex 20mg Tablet in patients with liver disease. Please consult your doctor.
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For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Nolvadex 20mg Tablet helps treat breast cancer.
- It also reduces the risk of cancer coming back and of getting cancer in the other breast.
- Use a reliable barrier contraceptive method (such as condoms) to prevent pregnancy while you are taking this medicine and for 2 months after you stop taking it.
- Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
- Inform your doctor if your periods become irregular, especially if associated with heavier bleeding.
- Do not stop taking the medicine without talking to your doctor first.
- Nolvadex 20mg Tablet helps treat breast cancer.
- It also reduces the risk of cancer coming back and of getting cancer in the other breast.
- Use a reliable barrier contraceptive method (such as condoms) to prevent pregnancy while you are taking this medicine and for 2 months after you stop taking it.
- Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
- Inform your doctor if your periods become irregular, especially if associated with heavier bleeding.
- Do not stop taking the medicine without talking to your doctor first.
Fact Box
Chemical Class
Nonsteroidal Antiestrogen
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Selective estrogen receptor modulators (SERM)- Breast Cx
Interaction with drugs
Taking Nolvadex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may increase the risk of recurrent breast cancer.
Do not consume Tamoxifen with Terbinafine.
Concurrent use may increase the risk of recurrent breast cancer.
Do not consume Tamoxifen with Paroxetine.
Concurrent use may increase the risk of recurrent breast cancer.
Do not consume Tamoxifen with Quinidine.
Allylestrenol may reduce the efficacy of Tamoxifen.
Do not consume Tamoxifen with Allylestrenol if you have or had breast cancer. If essential, consult your doctor.
Concurrent use may increase the risk of recurrent breast cancer.
Do not consume Tamoxifen with Bupropion.
Patient concerns
FAQs
What is Nolvadex 20mg Tablet and for what it is used for?
Nolvadex 20mg Tablet contains a medicine, Tamoxifen which works against a female sex hormone estrogen. It is used in the treatment of estrogen dependent breast cancer in women. It may also be used in the treatment of estrogen-dependent breast cancer in males.
How and in what dose should I use Nolvadex 20mg Tablet?
Take it as per the advice of your doctor. The number of doses you take each day and the duration depends on your medical problem. Take your tablet at about the same time every day to ensure consistent levels of medicine in your body. You can take it with or without food. Treatment with Nolvadex 20mg Tablet may be long term and you may require to take it for several years.
What if I forget to take Nolvadex 20mg Tablet?
If you forget to take a dose of Nolvadex 20mg Tablet, take it as soon as you remember. If it is near to your next dose, skip it and follow your usual dosing schedule. Do not take two doses at the same time to make up for the forgotten one.
What if I stop taking Nolvadex 20mg Tablet?
Do not stop taking Nolvadex 20mg Tablet, even if you start feeling well, unless your doctor tells you. Stopping it early may increase the risk of breast cancer coming back.
What are the common side effects of using Nolvadex 20mg Tablet?
The most common side effects associated with Nolvadex 20mg Tablet include menopausal symptoms such as hot flushes, night sweats, sleep disturbance, vaginal irritation, loss of sex drive and mood changes. It may also cause fluid retention, vaginal discharge, indigestion, nausea, and changes in your periods. If any of these bother you, consult with your doctor.
What is Nolvadex 20mg Tablet and for what it is used for?
Tamoxifen is a medicine, which works against estrogen, a female sex hormone. It is used in the treatment of estrogen dependent breast cancer in women. It may also be used in the treatment of estrogen-dependent breast cancer in males.
How and in what dose should I use Nolvadex 20mg Tablet?
Take it as per the advice of your doctor. The number of doses you take each day and the duration depends on your medical problem. Take your tablet at about the same time every day to ensure consistent levels of medicine in your body. You can take it with or without food. Treatment with Nolvadex 20mg Tablet may be long term and you may require to take it for several years.
What if I forget to take Nolvadex 20mg Tablet?
If you forget to take a dose of Nolvadex 20mg Tablet, take it as soon as you remember. If it is near to your next dose, skip it and follow your usual dosing schedule. Do not take two doses at the same time to make up for the forgotten one.
What if I stop taking Nolvadex 20mg Tablet?
Do not stop taking Nolvadex 20mg Tablet, even if you start feeling well, unless your doctor tells you. Stopping it early may increase the risk of breast cancer coming back.
What are the common side effects of using Nolvadex 20mg Tablet?
The most common side effects associated with Nolvadex 20mg Tablet include menopausal symptoms such as hot flushes, night sweats, sleep disturbance, vaginal irritation, loss of sex drive and mood changes. It may also cause fluid retention, vaginal discharge, indigestion, nausea, and changes in your periods. If any of these bother you, consult with your doctor.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Moy B, Lee RJ, Smith M. Natural Products in Cancer Chemotherapy: Hormones and Related Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1756-59.
- Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 716.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1311-14.
- Tamoxifen. Wilmington, Delaware: AstraZeneca Pharmaceuticals. [Accessed 03 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:
- CiplaMed. Tamoxifen citrate [Prescribing Information]. [Accessed 25 Jul. 2024] (online) Available from:
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Address: Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore
Country of origin: India
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