NP-Free Tablet SR is a combination medicine used for the treatment of neuropathic pain. This medicine decreases pain by controlling calcium channel activity of the nerve cells and increases the level of chemical messengers in the brain that help in regulating mood and protect nerve fibers.
NP-Free Tablet SR can be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by the doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine without talking to the doctor as it may worsen your symptoms.
Some common side effects of this medicine include constipation, difficulty in urination, blurred vision and dryness of mouth. It may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain and to control it, you should have a balanced diet and exercise regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.
Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of NP-Free
Constipation
Difficulty in urination
Weight gain
Sleepiness
Dizziness
Tiredness
Blurred vision
Dryness in mouth
Increased heart rate
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Uncoordinated body movements
How to use NP-Free Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. NP-Free Tablet SR may be taken with or without food, but it is better to take it at a fixed time.
How NP-Free Tablet works
NP-Free Tablet SR is a combination of four medicines: Pregabalin, Nortriptyline, Methylcobalamin and Vitamin D3. Pregabalin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Vitamin D3 helps transmit messages from nerve cells to other cells in the body. Together, they relieve neuropathic pain (pain from damaged nerves).
Safety advice
Alcohol
UNSAFE
NP-Free Tablet SR may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
NP-Free Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
NP-Free Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
NP-Free Tablet SR may cause side effects which could affect your ability to drive. As NP-Free Tablet SR may affect your alertness which may affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
NP-Free Tablet SR is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of NP-Free Tablet SR may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
NP-Free Tablet SR is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of NP-Free Tablet SR may not be needed in these patients. Please consult your doctor.
What if you forget to take NP-Free Tablet?
If you miss a dose of NP-Free Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
NP-Free Tablet SR is used to treat certain types of long-lasting pain caused by damage to nerves.
Inform your doctor if you are taking any other pain relieving medicines.
Inform your doctor if you have a history of seizures.
Immediately seek medical help if you experience hallucinations, fever, sweating, shivering, fast heart rate, muscle twitching, or loss of coordination.
Along with taking NP-Free Tablet SR, your doctor might advise you to undergo physiotherapy to get relief rom pain.
NP-Free Tablet SR is used to treat certain types of long-lasting pain caused by damage to nerves.
Inform your doctor if you are taking any other pain relieving medicines.
Inform your doctor if you have a history of seizures.
Immediately seek medical help if you experience hallucinations, fever, sweating, shivering, fast heart rate, muscle twitching, or loss of coordination.
Along with taking NP-Free Tablet SR, your doctor might advise you to undergo physiotherapy to get relief rom pain.
Terrible pain leg. like biting It's been so many times my wife facing this problem. Unbearable pain in whole leg sometimes its right and sometimes left. She has got the biting like sensation from inside.
Dr. Akshat Goel
Orthopaedics
Please refer to a Neuro-PhysicianApply Dynapar QPS spray and take Cap Nurokind-Gold twice daily and Tab Nervijen-NP in night for 5 days
I have a recurring numbness in my left leg, with pain that runs through like a current. Could you please help
Dr. Akshat Goel
Orthopaedics
Do Hot Fomentation and apply Dynapar QPS spray and take Tab Myospas-D thrice daily and Cap Nurokind-Gold twice daily and Tan Nervijen-NP in night for 5 days
Hi Dr, my tsh has increased from 2.08 to 5.5 from Dec to now.I am thinking of getting t3 and t4 tested .Should I get total t3 and total t4 tested or free t3 or free t4?
Hair loss so much losted and white white comes out from dcalp
Dr. Souvik Sardar
Dermatology
Use 5% regaine lotion - 1ml to apply once daily over dry scalp with fingers Continue for 4months Wash ur fingers after application NP effective medicines for white hairs
Do Hot Fomentation and apply Dynapar QPS spray and take Tab Myospas-D thrice daily and Tab Flotrip-forte thrice daily and Cap Nurokind-Gold twice daily for 5 daysAvoid forward bending and Avoid lifting heavy weight
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Pregabalin. Vega Baja, Puerto Rico: Pfizer Pharmaceuticals LLC; 2009. [Accessed 24 Apr. 2019] (online) Available from:
Drugs.com. Nortriptyline Pregnancy and Breastfeeding Warnings. [Accessed 24 Apr. 2019] (online) Available from:
Drugs.com. Cyanocobalamin Pregnancy and Breastfeeding Warnings. [Accessed 24 Apr. 2019] (online) Available from:
Drugs.com. Cholecalciferol Pregnancy and Breastfeeding Warnings. [Accessed 24 Apr. 2019] (online) Available from: