NP-Sure Tablet
Prescription Required
Product introduction
NP-Sure Tablet is a combination medicine used for the treatment of neuropathic pain. This medicine decreases the pain by stopping the movement of pain signals to the brain.
NP-Sure Tablet is taken by mouth, with or without food and preferably at bedtime. It is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the blood. Take this medicine in the dose and duration advised by your doctor as this is a habit-forming medicine. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop this medication suddenly without talking to the doctor.
Some common side effects of this medicine include constipation, difficulty in urination, weight gain, tiredness, and dryness in mouth. It may also cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain and to control it, you should exercise regularly and take a balanced diet. It is important to inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.
Before taking this medicine let your doctor know if you suffer from kidney or liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Uses of NP-Sure Tablet
Benefits of NP-Sure Tablet
In Treatment of Neuropathic pain
NP-Sure Tablet is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles, or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. It is thought to work by interfering with pain signals that travel through the damaged nerves and the brain.
Taking NP-Sure Tablet regularly will improve your physical and social functioning and overall quality of life. It takes a few weeks to work so you need to take it regularly even if you feel it is not doing any good. Once your symptoms have gone you should still keep taking the medicine until your doctor advises you to stop.
Taking NP-Sure Tablet regularly will improve your physical and social functioning and overall quality of life. It takes a few weeks to work so you need to take it regularly even if you feel it is not doing any good. Once your symptoms have gone you should still keep taking the medicine until your doctor advises you to stop.
Side effects of NP-Sure Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of NP-Sure
- Dryness in mouth
- Increased heart rate
- Sleepiness
- Dizziness
- Tiredness
- Weight gain
- Blurred vision
- Orthostatic hypotension (sudden lowering of blood pressure on standing)
- Uncoordinated body movements
- Increased appetite
- Increased libido
- Paresthesia (tingling or pricking sensation)
- Vertigo
- Vomiting
- Nausea
- Erectile dysfunction
- Joint pain
- Constipation
- Difficulty in urination
How to use NP-Sure Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. NP-Sure Tablet may be taken with or without food, but it is better to take it at a fixed time.
How NP-Sure Tablet works
NP-Sure Tablet is a combination of two medicines: Pregabalin and Nortriptyline. Pregabalin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Together, they relieve neuropathic pain (pain from damaged nerves).
Safety advice
Alcohol
UNSAFE
NP-Sure Tablet may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
NP-Sure Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
NP-Sure Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
NP-Sure Tablet may cause side effects which could affect your ability to drive.
As NP-Sure Tablet may affect your alertness which may affect your ability to drive.
As NP-Sure Tablet may affect your alertness which may affect your ability to drive.
Kidney
CAUTION
NP-Sure Tablet should be used with caution in patients with kidney disease. Dose adjustment of NP-Sure Tablet may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
NP-Sure Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of NP-Sure Tablet may not be needed in these patients. Please consult your doctor.
What if you forget to take NP-Sure Tablet?
If you miss a dose of NP-Sure Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
NP-Sure Tablet
₹14.8/Tablet
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₹27.2/tablet
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Nortipan Tablet
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Pregaba NT 75 mg/10 mg Tablet
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Nervite Tablet
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₹23.5/tablet
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Quick tips
- NP-Sure Tablet is used to treat certain types of long-lasting pain caused by damage to nerves.
- Inform your doctor if you are taking any other pain-relieving medicines.
- Inform your doctor if you have a history of seizures.
- Immediately seek medical help if you experience hallucinations, fever, sweating, shivering, fast heart rate, muscle twitching, or loss of coordination.
- Along with taking NP-Sure Tablet, your doctor might advise you to undergo physiotherapy to get relief from pain.
- NP-Sure Tablet is used to treat certain types of long-lasting pain caused by damage to nerves.
- Inform your doctor if you are taking any other pain-relieving medicines.
- Inform your doctor if you have a history of seizures.
- Immediately seek medical help if you experience hallucinations, fever, sweating, shivering, fast heart rate, muscle twitching, or loss of coordination.
- Along with taking NP-Sure Tablet, your doctor might advise you to undergo physiotherapy to get relief from pain.
Fact Box
Habit Forming
No
Therapeutic Class
NEURO CNS
Patient concerns
FAQs
What is NP-Sure Tablet?
NP-Sure Tablet is a combination of two medicines: Pregabalin and Nortriptyline. This medicine is useful in the treatment of nerve pain (neuropathic pain). It calms the damaged or overactive nerves by acting on the brain. Thereby, decreasing the pain sensation.
Can I stop taking NP-Sure Tablet when my pain is relieved?
No, you should not stop taking NP-Sure Tablet even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking NP-Sure Tablet, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain and sweating. You may need to gradually taper the dose before you stop the medication completely.
How to manage weight gain associated with the use of NP-Sure Tablet?
NP-Sure Tablet can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight.. However, preventing weight gain is easier than losing increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). DO not eat foods that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits, and sweets. If you feel hungry between meals, avoid eating junk food and eat fruits, vegetables and low-calorie foods. Regular exercise will prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.
Can the use of NP-Sure Tablet cause sleepiness or drowsiness?
Yes, NP-Sure Tablet may make you feel drowsy or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities at the beginning of your treatment until you know how the medicine affects you. Inform your doctor if you experience such episodes while taking this medicine.
Can the use of NP-Sure Tablet affect my sexual life?
The use of NP-Sure Tablet can affect the sexual life of both men and women. Most commonly caused problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while intercourse. If you experience these problems, discuss them with your doctor but do not stop taking NP-Sure Tablet.
Are there any serious side effects associated with the use of NP-Sure Tablet?
Serious side effects because of NP-Sure Tablet are uncommon and rare. Consult your doctor if you notice any of the following: changes in body temperature, difficulty in breathing, increased heartbeat (palpitations), weakness, unsteadiness when walking, reduced coordination or slowed reactions, unusual changes in mood or behavior (such as restlessness, nervousness or excitement), signs of depression, seeing or hearing things that are not there, irrational thinking, blurred or double vision, uncontrollable jerky eye movements, difficulty seeing, signs of frequent infections such as fever, severe chills, sore throat or mouth ulcers. These side effects are uncommon but may be serious and need urgent medical attention.
How long will the NP-Sure Tablet take to act?
An initial benefit with NP-Sure Tablet may be seen after 2 weeks of treatment. However, it may take around 2-3 months to see full benefit. It may even take longer in some patients.
What if I forget to take NP-Sure Tablet?
If you forget to take the scheduled dose of NP-Sure Tablet and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effects due to overdosage. If you are not sure what to do, consult your doctor about how to manage a situation like this.
What if I take too much of this drug by mistake?
In a situation like this, contact your doctor immediately or seek emergency help at the nearest hospital. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Symptoms of an overdose may include drowsiness, weakness, unsteadiness while walking, having double visions, slurred speech or diarrhea, confusion, blurred vision, dizziness, body temperature changes (low and high), difficulty in breathing and increased heartbeat.
Will NP-Sure Tablet be more effective if a higher than the recommended dosage is taken?
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.
Is there anything I need to avoid while taking NP-Sure Tablet?
NP-Sure Tablet may impair your thinking or reactions. Be careful while driving or doing an activity that requires you to be alert. Do not drink alcohol while you are taking NP-Sure Tablet. It can increase the effects of alcohol, which could be dangerous. Grapefruit and grapefruit juice may also interact with this medicine and cause unwanted side effects. Avoid exposure to sunlight or tanning beds. Use of NP-Sure Tablet can make you more prone to sunburns. Wear protective clothing and use sunscreen when you are outdoors during daytime.
How often should I see the doctor ?
You may need to see your doctor regularly if you have started to take NP-Sure Tablet. However, you must consult your doctor if the advised dosage of NP-Sure Tablet does not improve your symptoms or you continue experiencing some unwanted side effects that affect your routine activities.
Are there any special instructions regarding the storage and disposal of this medicine?
Keep your tablets in the pack until it is time to take them. Store them in a cool and dry place. Store them out of sight and reach of the children. Unused medications should be disposed of in special ways to ensure that pets, children and other people cannot consume them.
What is NP-Sure Tablet?
NP-Sure Tablet is a combination of two medicines: Pregabalin and Nortriptyline. This medicine is useful in the treatment of nerve pain (neuropathic pain). It calms the damaged or overactive nerves by acting on the brain. Thereby, decreasing the pain sensation.
Can I stop taking NP-Sure Tablet when my pain is relieved?
No, you should not stop taking NP-Sure Tablet even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking NP-Sure Tablet, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain and sweating. You may need to gradually taper the dose before you stop the medication completely.
How to manage weight gain associated with the use of NP-Sure Tablet?
NP-Sure Tablet can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight.. However, preventing weight gain is easier than losing increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). DO not eat foods that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits, and sweets. If you feel hungry between meals, avoid eating junk food and eat fruits, vegetables and low-calorie foods. Regular exercise will prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.
Can the use of NP-Sure Tablet cause sleepiness or drowsiness?
Yes, NP-Sure Tablet may make you feel drowsy or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities at the beginning of your treatment until you know how the medicine affects you. Inform your doctor if you experience such episodes while taking this medicine.
Can the use of NP-Sure Tablet affect my sexual life?
The use of NP-Sure Tablet can affect the sexual life of both men and women. Most commonly caused problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while intercourse. If you experience these problems, discuss them with your doctor but do not stop taking NP-Sure Tablet.
Are there any serious side effects associated with the use of NP-Sure Tablet?
Serious side effects because of NP-Sure Tablet are uncommon and rare. Consult your doctor if you notice any of the following: changes in body temperature, difficulty in breathing, increased heartbeat (palpitations), weakness, unsteadiness when walking, reduced coordination or slowed reactions, unusual changes in mood or behavior (such as restlessness, nervousness or excitement), signs of depression, seeing or hearing things that are not there, irrational thinking, blurred or double vision, uncontrollable jerky eye movements, difficulty seeing, signs of frequent infections such as fever, severe chills, sore throat or mouth ulcers. These side effects are uncommon but may be serious and need urgent medical attention.
How long will the NP-Sure Tablet take to act?
An initial benefit with NP-Sure Tablet may be seen after 2 weeks of treatment. However, it may take around 2-3 months to see full benefit. It may even take longer in some patients.
What if I forget to take NP-Sure Tablet?
If you forget to take the scheduled dose of NP-Sure Tablet and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effects due to overdosage. If you are not sure what to do, consult your doctor about how to manage a situation like this.
What if I take too much of this drug by mistake?
In a situation like this, contact your doctor immediately or seek emergency help at the nearest hospital. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Symptoms of an overdose may include drowsiness, weakness, unsteadiness while walking, having double visions, slurred speech or diarrhea, confusion, blurred vision, dizziness, body temperature changes (low and high), difficulty in breathing and increased heartbeat.
Will NP-Sure Tablet be more effective if a higher than the recommended dosage is taken?
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.
Is there anything I need to avoid while taking NP-Sure Tablet?
NP-Sure Tablet may impair your thinking or reactions. Be careful while driving or doing an activity that requires you to be alert. Do not drink alcohol while you are taking NP-Sure Tablet. It can increase the effects of alcohol, which could be dangerous. Grapefruit and grapefruit juice may also interact with this medicine and cause unwanted side effects. Avoid exposure to sunlight or tanning beds. Use of NP-Sure Tablet can make you more prone to sunburns. Wear protective clothing and use sunscreen when you are outdoors during daytime.
How often should I see the doctor ?
You may need to see your doctor regularly if you have started to take NP-Sure Tablet. However, you must consult your doctor if the advised dosage of NP-Sure Tablet does not improve your symptoms or you continue experiencing some unwanted side effects that affect your routine activities.
Are there any special instructions regarding the storage and disposal of this medicine?
Keep your tablets in the pack until it is time to take them. Store them in a cool and dry place. Store them out of sight and reach of the children. Unused medications should be disposed of in special ways to ensure that pets, children and other people cannot consume them.
What is NP-Sure Tablet?
NP-Sure Tablet is a combination of two medicines: Pregabalin and Nortriptyline. This medicine is useful in the treatment of nerve pain (neuropathic pain). It calms the damaged or overactive nerves by acting on the brain. Thereby, decreasing the pain sensation.
Can I stop taking NP-Sure Tablet when my pain is relieved?
No, you should not stop taking NP-Sure Tablet even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking NP-Sure Tablet, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain and sweating. You may need to gradually taper the dose before you stop the medication completely.
How to manage weight gain associated with the use of NP-Sure Tablet?
NP-Sure Tablet can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight.. However, preventing weight gain is easier than losing increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). DO not eat foods that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits, and sweets. If you feel hungry between meals, avoid eating junk food and eat fruits, vegetables and low-calorie foods. Regular exercise will prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.
Can the use of NP-Sure Tablet cause sleepiness or drowsiness?
Yes, NP-Sure Tablet may make you feel drowsy or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities at the beginning of your treatment until you know how the medicine affects you. Inform your doctor if you experience such episodes while taking this medicine.
Can the use of NP-Sure Tablet affect my sexual life?
The use of NP-Sure Tablet can affect the sexual life of both men and women. Most commonly caused problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while intercourse. If you experience these problems, discuss them with your doctor but do not stop taking NP-Sure Tablet.
Are there any serious side effects associated with the use of NP-Sure Tablet?
Serious side effects because of NP-Sure Tablet are uncommon and rare. Consult your doctor if you notice any of the following: changes in body temperature, difficulty in breathing, increased heartbeat (palpitations), weakness, unsteadiness when walking, reduced coordination or slowed reactions, unusual changes in mood or behavior (such as restlessness, nervousness or excitement), signs of depression, seeing or hearing things that are not there, irrational thinking, blurred or double vision, uncontrollable jerky eye movements, difficulty seeing, signs of frequent infections such as fever, severe chills, sore throat or mouth ulcers. These side effects are uncommon but may be serious and need urgent medical attention.
How long will the NP-Sure Tablet take to act?
An initial benefit with NP-Sure Tablet may be seen after 2 weeks of treatment. However, it may take around 2-3 months to see full benefit. It may even take longer in some patients.
What if I forget to take NP-Sure Tablet?
If you forget to take the scheduled dose of NP-Sure Tablet and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effects due to overdosage. If you are not sure what to do, consult your doctor about how to manage a situation like this.
What if I take too much of this drug by mistake?
In a situation like this, contact your doctor immediately or seek emergency help at the nearest hospital. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Symptoms of an overdose may include drowsiness, weakness, unsteadiness while walking, having double visions, slurred speech or diarrhea, confusion, blurred vision, dizziness, body temperature changes (low and high), difficulty in breathing and increased heartbeat.
Will NP-Sure Tablet be more effective if a higher than the recommended dosage is taken?
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.
Is there anything I need to avoid while taking NP-Sure Tablet?
NP-Sure Tablet may impair your thinking or reactions. Be careful while driving or doing an activity that requires you to be alert. Do not drink alcohol while you are taking NP-Sure Tablet. It can increase the effects of alcohol, which could be dangerous. Grapefruit and grapefruit juice may also interact with this medicine and cause unwanted side effects. Avoid exposure to sunlight or tanning beds. Use of NP-Sure Tablet can make you more prone to sunburns. Wear protective clothing and use sunscreen when you are outdoors during daytime.
How often should I see the doctor ?
You may need to see your doctor regularly if you have started to take NP-Sure Tablet. However, you must consult your doctor if the advised dosage of NP-Sure Tablet does not improve your symptoms or you continue experiencing some unwanted side effects that affect your routine activities.
Are there any special instructions regarding the storage and disposal of this medicine?
Keep your tablets in the pack until it is time to take them. Store them in a cool and dry place. Store them out of sight and reach of the children. Unused medications should be disposed of in special ways to ensure that pets, children and other people cannot consume them.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Pregabalin. Vega Baja, Puerto Rico: Pfizer Pharmaceuticals LLC; 2009. [Accessed 22 Apr. 2019] (online) Available from:
- Pregabalin. New York, New York: Pfizer; 2004 [revised Jun 2011]. [Accessed 22 Apr. 2019] (online) Available from:
- Pregabalin and Nortriptyline [Product Information]. Ahmedabad, Gujarat: La Renon Healthcare Limited. [Accessed 28th Sept. 2023] (online) Available from:
- Pregabalin+Nortriptyline [Prescribing Information]. Mumbai, Maharashtra: Alkem Laboratories Limited. [Accessed 28th Sept. 2023] (online) Available from:
Marketer details
Name: Surewin Healthcare
Address: #121, 1st Floor, Industrial Area, Phase - 1, Panchkula, Haryana - 134113
Country of origin: India
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