Obetohep 5mg Tablet
Prescription Required
Product introduction
Obetohep 5mg Tablet is used in alone or in combination therapy to treat primary biliary cirrhosis. It helps improve the liver function by inhibiting the production of bile acid and increasing the removal of bile acid from the liver. This reduces the bile acid in the liver and hence prevents its toxic effects.
Obetohep 5mg Tablet may be taken with or without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. You should always complete the full course of the medicine as prescribed by your doctor. Do not stop taking it until you have finished.
The most common side effects of this medicine include itching, fatigue, rash, throat pain, dizziness, constipation, joint pain, eczema, and thyroid disorders. If you experience any of these side effects that does not resolve on its own or get worse, you should let your doctor.
Before taking the medicine, tell your doctor if you have any other medical conditions. You should also let your doctor know about all the other medicines you are taking (if any), as they may affect or be affected by this medicine. Consult your doctor before using this medicine if you are pregnant or breastfeeding.
Uses of Obetohep Tablet
- Treatment of Primary biliary cirrhosis
Benefits of Obetohep Tablet
In Treatment of Primary biliary cirrhosis
Primary biliary cholangitis is a type of liver disease that gradually gets worse over time. It does not always have symptoms but, over time, it can lead to liver failure. Obetohep 5mg Tablet is used to treat this condition and may be used by itself or with other medicines. It can help prevent or delay liver damage in most people, especially if you start taking it in the early stages. Once you start this treatment, it is likely that you will be taking it for the rest of your life. To make the medicine more effective and for general health benefits, you can help yourself by stopping smoking, keeping a healthy weight, and not drinking too much alcohol.
Side effects of Obetohep Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Obetohep
- Throat pain
- Itching
- Fatigue
- Abdominal discomfort
- Rash
- Joint pain
- Oropharyngeal pain
- Dizziness
- Constipation
- Peripheral edema
- Palpitations
- Fever
- Thyroid disorders
- Eczema
How to use Obetohep Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Obetohep 5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Obetohep Tablet works
Obetohep 5mg Tablet stimulates Farnesoid X receptor (FXR), a chemical that regulates synthesis and transport of bile acid, lipid metabolism and regulation of glucose levels. Obetohep 5mg Tablet inhibits bile acid synthesis and increases bile acid secretions. This reduces the bile acid pool in the liver and hence prevents its toxic effects. Therefore, it helps to improve liver function.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Obetohep 5mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Obetohep 5mg Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Obetohep 5mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Obetohep 5mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Obetohep 5mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Obetohep 5mg Tablet may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
Obetohep 5mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Obetohep 5mg Tablet may be needed. Please consult your doctor.
What if you forget to take Obetohep Tablet?
If you miss a dose of Obetohep 5mg Tablet, skip it and continue with your normal schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Obetohep 5mg Tablet
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Quick tips
- Obetohep 5mg Tablet is used for the treatment of primary biliary cirrhosis.
- Your liver function will be monitored closely while on treatment with Obetohep 5mg Tablet.
- Eat a well-balanced diet and indulge in some sort of physical activity daily in order to reduce fatigue and improve well-being.
- Itching is one of the common side effects of Obetohep 5mg Tablet. Follow these tips to manage itching:
a) Keeping cool will also tend to reduce itch, compared to being warm. Cool showers or cold flannels may be helpful.
b)Dry skin can make the itch worse, so using liberal amounts of moisturizer is useful if you have dry skin.
c) Do not scratch as scratching will generally make it worse. If scratching is irresistible it may help to rub the itchy area with an ice cube.
Fact Box
Chemical Class
Dihydroxy bile acids, alcohols and derivatives
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Hepatoprotectives
Interaction with drugs
Taking Obetohep with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Obeticholic acid may raise blood levels of Theophylline.
watch out for symptoms such as nausea, palpitations or headaches and consult your doctor if you experience them. They may
Cholestyramine may reduce the efficacy of Obeticholic acid.
To take Obeticholic acid, ensure a gap of at least 6 hours before or after taking Cholestyramine.
Obeticholic acid may raise blood levels of Tizanidine.
watch out for symptoms of Tizanidine side effects such as breathlessness, fatigue, drowsiness, sedation or faintness or vomi
Obeticholic acid may raise blood levels of Warfarin.
Your doctor may frequently monitor your blood clotting time and adjust the dose of Warfarin accordingly.
Colesevelam may reduce the efficacy of Obeticholic acid.
To take Obeticholic acid, ensure a gap of at least 6 hours before or after taking Colesevelam.
Patient concerns
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Obeticholic acid [FDA Label]. New York, NY: Intercept Pharmaceuticals, Inc.; 2016. [Accessed 30 Jun. 2020]. (online) Available from:
- Obeticholic Acid [Package Infirmation Sheet]. Haridwar, Uttarakhand: Akums Drugs & Pharmaceuticals Ltd.; 2020. [Accessed 20 Feb. 2024] (online) Available from:
Marketer details
Name: Alkem Laboratories Ltd
Address: Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Country of origin: India
Expires on or after: May, 2025
A licensed vendor partner from your nearest location will deliver Obetohep 5mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: May, 2025
A licensed vendor partner from your nearest location will deliver Obetohep 5mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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