Offmigran Tablet
Prescription Required
Product introduction
Offmigran Tablet is a medicine used to prevent and treat migraine. It blocks the release of certain chemical messengers that cause pain and inflammation. It also blocks the signals in the brain that cause nausea and vomiting associated with migraine.
Offmigran Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose and duration will depend on what you are using it for and how well it helps your symptoms. Use it regularly and do not discontinue using it until the doctor tells you it is alright to stop.
It may cause side effects like sedation, orthostatic hypotension (sudden lowering of blood pressure on standing), drowsiness, urinary retention, and dryness in mouth in some patients. If you experience any of such side effects that do not go away or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. In general, you should try to use the smallest amount necessary to control your symptoms.
Before using the medicine, you should tell your doctor if you have any other illnesses or disorders. It may also affect, or be affected by, some other medicines you are using so let your doctor know all the other medicines you are taking. It should be used with caution in patients who are alcoholic or have liver or kidney disease. Pregnant and breastfeeding women should consult their doctors first before using the medicine.
Uses of Offmigran Tablet
Side effects of Offmigran Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Offmigran
- Dryness in mouth
- Constipation
- Sedation
- Orthostatic hypotension (sudden lowering of blood pressure on standing)
- Drowsiness
- Urinary retention
- Increased heart rate
- Muscle pain
How to use Offmigran Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Offmigran Tablet is to be taken with food.
How Offmigran Tablet works
Offmigran Tablet is a combination of caffeine, ergotamine, paracetamol, and prochlorperazine. Ergotamine constricts blood vessels in the brain, reducing migraine pain caused by dilation. Caffeine enhances this effect by boosting ergotamine’s action. Paracetamol provides pain relief, while prochlorperazine helps control nausea and vomiting, which are common migraine symptoms. Together, these components work to alleviate headache pain and associated symptoms.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Offmigran Tablet.
Pregnancy
UNSAFE
Offmigran Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Offmigran Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Occasional short-term use of Offmigran Tablet for the treatment of nausea and vomiting poses little risk to the breastfed infant.
Occasional short-term use of Offmigran Tablet for the treatment of nausea and vomiting poses little risk to the breastfed infant.
Driving
UNSAFE
Offmigran Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Offmigran Tablet should be used with caution in patients with kidney disease. Dose adjustment of Offmigran Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Offmigran Tablet should be used with caution in patients with liver disease. Dose adjustment of Offmigran Tablet may be needed. Please consult your doctor.
What if you forget to take Offmigran Tablet?
If you miss a dose of Offmigran Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Offmigran Tablet
₹11.1/Tablet
Vasograin Tablet
Cadila Pharmaceuticals Ltd
₹9.64/tablet
13% cheaper
NT Grain Tablet
Intas Pharmaceuticals Ltd
₹3.93/tablet
65% cheaper
Livigrain Tablet
Lividus Pharmaceuticals Pvt Ltd
₹4.85/tablet
56% cheaper
Vasograin Tablet
Cadila Pharmaceuticals Ltd
₹7.58/tablet
32% cheaper
Neuromol Plus Tablet
Bilcare Ltd
₹2.71/tablet
76% cheaper
Quick tips
- Offmigran Tablet helps in the treatment and prevention of migraine headaches.
- Do not take it to treat an acute attack of migraine.
- Some tips that may help avoid a migraine attack:
- Have your meals at the same time everyday
- Avoid bright lights and extreme temperatures
- Avoid loud music and noisy places
- Avoid chocolates, cheese, processed food, alcohol and smoking
- Get sufficient sleep and avoid stress
- It should be taken at night-time before going to bed.
- It may cause sleepiness. Do not drive or do anything that requires mental focus until you know how Offmigran Tablet affects you.
- Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough-and-cold) without asking your doctor first.
- Do not stop taking the medication suddenly as it can cause worsening of headaches.
Fact Box
Habit Forming
No
Therapeutic Class
NEURO CNS
Patient concerns
FAQs
What is Offmigran Tablet?
Offmigran Tablet is a combination of four medicines: Paracetamol, Ergotamine, Caffeine and Prochlorperazine. This medicine is used in the treatment of migraine symptoms like a headache, nausea and vomiting. Ergotamine prevents blood vessels in the head from expanding. Caffeine increases the absorption of ergotamine and also narrows the widened blood vessels. Paracetamol blocks the release of certain chemical messengers in the brain that causes pain. Prochlorperazine is an antiemetic which prevents vomiting by blocking signals to the part of your brain that cause nausea/vomiting.
What can cause or trigger a migraine attack?
Certain physical or environmental factors, such as foods, hormonal changes, weather and stress can lead to or “trigger” a migraine. However, it is important to remember that triggers can be different for everyone. That is why, to help prevent migraine attacks, you need to figure out which triggers affect you and which ones do not. Keeping a headache diary is an effective way to track triggers, and it will help you talk to your healthcare professional about your condition.
Can I stop taking Offmigran Tablet when my migraine symptoms are relieved?
Offmigran Tablet is usually used for prevention and treatment of migraine attack. Offmigran Tablet should be continued as advised by the doctor.
Can the use of Offmigran Tablet cause constipation?
Yes, the use of Offmigran Tablet can cause constipation. Lifestyle changes like eating a good amount of high-fiber foods such as fresh fruits, vegetables and cereals, drinking plenty of water or other fluids and regular exercise can help relieve constipation.
Can the use of Offmigran Tablet cause dry mouth?
Yes, the use of Offmigran Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry. Try to avoid foods that are acidic (like lemons), spicy and salty.
Can I take a higher than the recommended dose of this medicine?
No, taking a higher than the recommended dose of Offmigran Tablet can increase the risk of side effects. If you are experiencing increased severity of migraine attacks which are not relieved by the recommended dose of this medicine, please consult your doctor for re-evaluation.
Does Offmigran Tablet expire?
Yes, Offmigran Tablet does expire. Please check the expiry date written on the pack of this medicine. Do not use Offmigran Tablet after the expiry date.
What is Offmigran Tablet?
Offmigran Tablet is a combination of four medicines: Paracetamol, Ergotamine, Caffeine and Prochlorperazine. This medicine is used in the treatment of migraine symptoms like a headache, nausea and vomiting. Ergotamine prevents blood vessels in the head from expanding. Caffeine increases the absorption of ergotamine and also narrows the widened blood vessels. Paracetamol blocks the release of certain chemical messengers in the brain that causes pain. Prochlorperazine is an antiemetic which prevents vomiting by blocking signals to the part of your brain that cause nausea/vomiting.
What is a migraine?
A migraine is characterized by severe throbbing pain on one side of the head. The pain is usually pulsating in nature and is accompanied by nausea, vomiting, and sensitivity to light, sound and smell. The symptoms and severity vary from person to person.
What can cause or trigger a migraine attack?
Certain physical or environmental factors, such as foods, hormonal changes, weather and stress can lead to or “trigger” a migraine. However, it is important to remember that triggers can be different for everyone. That is why, to help prevent migraine attacks, you need to figure out which triggers affect you and which ones do not. Keeping a headache diary is an effective way to track triggers, and it will help you talk to your healthcare professional about your condition.
Can I stop taking Offmigran Tablet when my migraine symptoms are relieved?
Offmigran Tablet is usually used for prevention and treatment of migraine attack. Offmigran Tablet should be continued as advised by the doctor.
Can the use of Offmigran Tablet cause constipation?
Yes, the use of Offmigran Tablet can cause constipation. Lifestyle changes like eating a good amount of high-fiber foods such as fresh fruits, vegetables and cereals, drinking plenty of water or other fluids and regular exercise can help relieve constipation.
Can the use of Offmigran Tablet cause dry mouth?
Yes, the use of Offmigran Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry. Try to avoid foods that are acidic (like lemons), spicy and salty.
Can I take a higher than the recommended dose of this medicine?
No, taking a higher than the recommended dose of Offmigran Tablet can increase the risk of side effects. If you are experiencing increased severity of migraine attacks which are not relieved by the recommended dose of this medicine, please consult your doctor for re-evaluation.
Does Offmigran Tablet expire?
Yes, Offmigran Tablet does expire. Please check the expiry date written on the pack of this medicine. Do not use Offmigran Tablet after the expiry date.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Tulane University: School of Medicine. Caffeine. [Accessed 29 Jan. 2019] (online) Available from:
- Prochlorperazine maleate. Skipton, UK: Dales Pharmaceuticals Limited; 2016. [Accessed 28 Mar. 2019] (online) Available from:
- Leeford Healthcare. Ergotamine Tartrate, Caffeine Monohydrate, Paracetamol, & Prochlorperazine Maleate [Product Description]. [Accessed 16 Sep. 2024] (online) Available from:
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