Olet Plus 20 mg/5 mg Tablet is a prescription medicine used in the treatment of bipolar depression. It works by increasing the level of chemical messengers in the brain which improves mood and physical symptoms of depression.

Olet Plus 20 mg/5 mg Tablet may be taken with or without food, preferably at the same time each day. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this medicine include nausea, vomiting, diarrhea, constipation, dry mouth, muscle rigidity, restlessness, tremor, delayed ejaculation, anorgasmia (decreased orgasm), and low sexual desire. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. However, these are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you.

Before taking Olet Plus 20 mg/5 mg Tablet, inform your doctor if you are suffering from thyroid or kidney disease, epilepsy, Parkinson’s disease, glaucoma, or any heart disease. You should not take this medicine if you are under the influence of alcohol or any sleep-inducing, cough, and/ or allergy medication. You should avoid alcohol while taking Olet Plus 20 mg/5 mg Tablet, as it may worsen certain side effects.

Olet Plus 20 mg/5 mg Tablet can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.

Uses of Olet Plus Tablet

Bipolar depression

Side effects of Olet Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Olet Plus

Weight gain
Sleepiness
Dryness in mouth
Edema (swelling)
Ecchymosis (discoloration of the skin resulting from bleeding underneath)
Memory loss
Breast pain
Insomnia (difficulty in sleeping)

How to use Olet Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Olet Plus 20 mg/5 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Olet Plus Tablet works

Olet Plus 20 mg/5 mg Tablet is a combination of two medicines: Fluoxetine and Olanzapine. They work by increasing the activity of certain chemicals called serotonin, norepinephrine, and dopamine in the brain. These chemicals help relieve the symptoms of bipolar depression.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Olet Plus 20 mg/5 mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Olet Plus 20 mg/5 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Olet Plus 20 mg/5 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Olet Plus 20 mg/5 mg Tablet may cause side effects which could affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Olet Plus 20 mg/5 mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Olet Plus 20 mg/5 mg Tablet may not be needed in these patients. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Olet Plus 20 mg/5 mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Olet Plus 20 mg/5 mg Tablet may not be needed in these patients. Please consult your doctor.

What if you forget to take Olet Plus Tablet?

If you miss a dose of Olet Plus 20 mg/5 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Olet Plus 20 mg/5 mg Tablet

₹9.08/Tablet

Fostera 20mg/5mg Tablet

Intas Pharmaceuticals Ltd

₹13.4/tablet

48% costlier

Oleanz Plus Tablet

Sun Pharmaceutical Industries Ltd

₹14.5/tablet

60% costlier

Olanex F Tablet

Emcure Pharmaceuticals Ltd

₹15.7/tablet

73% costlier

Oltha Plus Tablet

Shine Pharmaceuticals Ltd

₹12.5/tablet

38% costlier

Olay Plus Tablet

Talent India

₹10.8/tablet

19% costlier

View all substitutes

Quick tips

You have been prescribed Olet Plus 20 mg/5 mg Tablet for the treatment of bipolar disorder with depression.
Take it in the evening as it can make you feel sleepy.
It may take 4 to 6 weeks to experience the full benefits of the medication.
Don't drive or do anything requiring concentration until you know how it affects you.
It may cause increase in weight, blood sugar, cholesterol, and triglycerides (fat). Eat healthy and exercise regularly.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
You have been prescribed Olet Plus 20 mg/5 mg Tablet for the treatment of bipolar disorder with depression.
Take it in the evening as it can make you feel sleepy.
It may take 4 to 6 weeks to experience the full benefits of the medication.
Don't drive or do anything requiring concentration until you know how it affects you.
It may cause increase in weight, blood sugar, cholesterol, and triglycerides (fat). Eat healthy and exercise regularly.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.

Fact Box

Habit Forming

Therapeutic Class

NEURO CNS

Patient concerns

Mujhe bipolar 2 depression hai

Dr. Jyoti Kapoor Madan

Psychiatry

Bipolar disorder type 2 is like BAD type 1, except there are majorly Depressive episodes interspersed with hypomanic episodes. Bipolar Affective Disorder is a chronic problem caused by Neuro chemical disturbance in brain. It is characterised by excessive mood swings leading to disruption in routine life. Treatment is with mood stabilizer medicines and antipsychotic medicines which may need to continue throughout life. Please see a psychiatrist for further guidance.

Bipolar mood anxiety depression and jolts in body

Dr. Jyoti Kapoor Madan

Psychiatry

Bipolar Affective Disorder is a chronic problem caused by Neuro chemical disturbance in brain. It is characterised by excessive mood swings leading to disruption in routine life. Treatment is with mood stabilizer medicines and antipsychotic medicines which may need to continue throughout life. Please see a psychiatrist for further guidance.

I am suffering from bipolar disorder, depression and anxiety. Taking lithium carbonate, sodium valproate, antidepressant and benzodizepines since 6 months. Not feeling well

Dr. Venkatraju Kalidindi

Psychiatry

Dear 1mg user, medicines gives quick relief and has side effects too so consult your doctor and see how to reduce dose and control totally, later you can take counselling that really helps you.

Suffering from bipolar disorder

Dr. Jyoti Kapoor Madan

Psychiatry

Bipolar disorder treatment needed

Dr. Jyoti Kapoor Madan

Psychiatry

User feedback

Patients taking Olet Plus 20 mg/5 mg Tablet

Once A Day

87%

Twice A Day

Alternate Day

Thrice A Day

How much was the improvement?

Average

56%

Excellent

44%

What were the side-effects while using Olet Plus 20 mg/5 mg Tablet?

No Side Effec*

100%

*No Side Effect

How do you take Olet Plus Tablet?

With food

67%

With or witho*

33%

*With or without food

Please rate Olet Plus 20 mg/5 mg Tablet on price

Average

78%

Expensive

22%

Top Psychiatrists

Dr. Jyoti Kapoor Madan

MBBS, DNB, Diploma, Fellowship

4.2 ★

4.6 ★

4.6 ★

4.4 ★

4.3 ★

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Medscape. Fluoxetine+Olanzapine. [Accessed 23 Apr. 2019] (online) Available from:
Olanzapine and fluoxetine hydrochloride [Prescribing Information]. Indianapolis, IN: Eli Lilly and Company; 2011. [Accessed 16 Sep. 2024] (online) Available from: