Ondem Syrup
Prescription Required
Your child’s medicine at a glance
Ondem Syrup is a medicine given to children to help treat nausea and vomiting. It is mainly given to treat nausea and vomiting associated with surgery, chemotherapy, radiotherapy, and stomach/intestinal infection. It also helps treat vomiting that is caused as a side effect of medicines like painkillers.
Ondem Syrup may be given before or after meals. To control vomiting caused due to chemotherapy, give this medicine to your child 30 minutes before the procedure. Give it 1 to 2 hours before a radiotherapy session and 1 hour before surgery to prevent your child from vomiting post these procedures. If your child expels out the medicine within 30 minutes of the intake, help your child calm down and repeat the dose. Do not double dose if it is already time for the next dose.
Ondem Syrup may cause some temporary side effects such as headache, constipation, diarrhea, and fatigue. These side effects usually subside once your child’s body adapts to the medicine. In case these side effects persist or become bothersome, do reach out to the doctor on a priority basis.
Let the doctor know about all the medicines your child is taking, including painkillers, antibiotics, or medicines taken to treat depression. Also, inform the doctor if your child has a history of liver problems, kidney malfunction, blockage in the gastrointestinal tract, heart problems, or allergies to any medicine, its ingredients, or a food product. This information is very important for dose alterations and for planning your child’s overall treatment.
Side effects of Ondem Syrup in children
Ondem Syrup does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-
Common side effects of Ondem
- Constipation
- Diarrhea
- Fatigue
- Headache
How can I give Ondem Syrup to my child?
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Ondem Syrup may be taken with or without food, but it is better to take it at a fixed time.
How Ondem Oral Solution works
During radiotherapy, chemotherapy, abdominal infection, or any major surgeries, the dead cells in the body start releasing a chemical called serotonin directly into the blood. Later, this stimulates special centers in the body that are responsible for inducing vomiting in your child. Giving Ondem Syrup just before the procedure helps block the effect of this chemical on vomiting centers of the brain and prevents vomiting.
Safety advice
Kidney
SAFE IF PRESCRIBED
Ondem Syrup is safe to use in patients with kidney disease. No dose adjustment of Ondem Syrup is recommended.
Liver
CAUTION
Ondem Syrup should be used with caution in patients with liver disease. Dose adjustment of Ondem Syrup may be needed. Please consult your doctor.
In severe liver disease, do not exceed the prescribed dose and consult your child’s doctor.
In severe liver disease, do not exceed the prescribed dose and consult your child’s doctor.
What if I forget to give Ondem Syrup to my child?
Do not panic. Give the missed dose as soon as you remember. However, you must skip the missed dose if it’s almost time for the next dose. Do not give a double dose and follow the prescribed dosing schedule.
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Quick tips
- Ondem Syrup effectively controls nausea and bouts of vomiting reflex in children undergoing chemotherapy or radiotherapy sessions.
- It is fast-acting and starts working within 30 minutes.
- Practice self-care measures:
- Give plenty of fluids to your child to avoid dehydration
- Avoid giving fried and spicy food or heavy meals to your child.
- Ensure that your child eats slowly and in small proportions.
Fact Box
Chemical Class
Carbazole Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Serotonin 5-HT3 Receptor Antagonists
Interaction with drugs
Taking Ondem with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Fluconazole with Ondansetron.
Concomitant use may affect heart rhythm and can be fatal.
Do not consume Domperidone with Ondansetron.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Hydroxyzine with Ondansetron.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Voriconazole with Ondansetron.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Tetrabenazine with Ondansetron.
Patient concerns
User feedback
Patients taking Ondem Syrup
Twice A Day
40%
Once A Day
40%
Thrice A Day
20%
What are you using Ondem Oral Solution for?
Vomiting
97%
Others
3%
How much was the improvement?
Average
48%
Poor
28%
Excellent
24%
What were the side-effects while using Ondem Syrup?
No Side Effec*
38%
Constipation
25%
Diarrhea
12%
Fatigue
12%
Flushing (sen*
12%
*No Side Effect, Flushing (sense of warmth in the face, ears, neck and trunk)
How do you take Ondem Oral Solution?
Empty stomach
57%
With or witho*
38%
With food
5%
*With or without food
Please rate Ondem Syrup on price
Not Expensive
47%
Expensive
26%
Average
26%
FAQs
What is Ondem Syrup used for?
Ondem Syrup is generally given before any major surgery or before chemotherapy and radiotherapy sessions. In case your child is about to undergo any of the above procedures, the doctor may ask you to give Ondem Syrup to your child to prevent vomiting post-procedure. Apart from this, Ondem Syrup is also found useful in treating vomiting caused due to diseases of the stomach. In such a case, your child’s doctor may prescribe giving Ondem Syrup to your child for a few days. Stick to the dose for best results.
What if my child takes too much Ondem Syrup?
Ondem Syrup is unlikely to cause harm if you give an extra dose by mistake. However, you must still speak to your child’s doctor immediately. Sometimes, excessive intake of Ondem Syrup can cause some serious side effects like excess sleepiness, agitation, rapid heartbeat, hypertension, flushing, dilated pupils, sweating, involuntary muscle jerk, uncontrolled eye movements, overactive reflexes, and seizures. These symptoms are collectively known as serotonin syndrome. If any of these appear, consult the doctor without any delay.
How should Ondem Syrup be stored?
Ondem Syrup should be stored at room temperature, in a dry place, away from direct heat and light. Also, keep all the medicines out of the reach and sight of children to avoid any accidental intake.
Can other medicines be given at the same time as Ondem Syrup?
Ondem Syrup can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Ondem Syrup. Also, check with your child’s doctor before giving any medicine to your child.
In what conditions do I need to call my child’s doctor right away?
Call your child’s doctor immediately if your child develops symptoms of serotonin syndrome like irregular heartbeat, green-colored vomiting, inability to pass wind, pale skin and eyes, dark-colored urine, restlessness, and insomnia.
My child is having a migraine and is on medication. Can I give Ondem Syrup along with it?
Avoid combining Ondem Syrup with such medicines because concomitant use of Ondem Syrup with medicines meant to treat depression or migraine results in serotonin syndrome. Consult your child’s doctor before giving any medicine to your child.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1341-42.
- Katzung BG. Histamine, Serotonin, & the Ergot Alkaloids. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 285
- Ondansetron hydrochloride [FDA Label]. Research Triangle Park, NC: GlaxoSmithKline; 2016. [Accessed 04 Jan. 2020] (online) Available from:
- Children’s Minnesota. Patient & Family Education Materials: Ondansetron (Zofran). [Accessed 04 Jan. 2020] (online) Available from:
- Ondansetron [Summary of Product Characteristics]. Solan, Himachal Pradesh: Cachet Pharmaceuticals PVT. LTD.; 2024. [Accessed 25 Jul. 2024] (online) Available from:
Marketer details
Name: Alkem Laboratories Ltd
Address: Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Country of origin: India
Expires on or after: January, 2026
A licensed vendor partner from your nearest location will deliver Ondem Syrup. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: January, 2026
A licensed vendor partner from your nearest location will deliver Ondem Syrup. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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