Ondrea 500mg Capsule
Prescription Required
Product introduction
Ondrea 500mg Capsule is used in the treatment of some kinds of cancer and to prevent painful episodes associated with sickle cell anemia. It may be also used to treat some other conditions. It is sometimes used with certain other medicines as part of combination chemotherapy.
Ondrea 500mg Capsule can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include hematological disorders, gastrointestinal symptoms, eating disorders, and weight loss. This medicine may reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine.
Before taking it, tell your doctor if you have bleeding, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Ondrea 500mg Capsule can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include hematological disorders, gastrointestinal symptoms, eating disorders, and weight loss. This medicine may reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine.
Before taking it, tell your doctor if you have bleeding, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Ondrea Capsule
Side effects of Ondrea Capsule
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ondrea
- Skin cancer
- Azoospermia (absence of sperms)
- Decreased appetite
- Fever
- Oligospermia (low sperm count)
- Bone marrow suppression
- Hallucination
- Convulsion
- Peripheral neuropathy (tingling and numbness of feet and hand)
- Pulmonary fibrosis
- Pulmonary edema
- Pancreatic inflammation
- Liver toxicity
- Cutaneous vasculitis
- Increased uric acid level in blood
- Hematological disorder
- Gastrointestinal disorder
- Eating disorder
How to use Ondrea Capsule
Take this medicine in the dose and duration as advised by your doctor. Ondrea 500mg Capsule may be taken with or without food, but it is better to take it at a fixed time.
How Ondrea Capsule works
In cancer, Ondrea 500mg Capsule works by blocking an enzyme (ribonucleotide reductase) which is required for synthesis of DNA. This prevents the cancer cells from growing and multiplying. In sickle cell disease, it works by increasing fetal haemoglobin (HbF) levels in red blood cells (RBCs). This helps the RBCs assume a normal shape, improves blood flow and protects against complications such as painful sickle cell episodes.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Ondrea 500mg Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Ondrea 500mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Ondrea 500mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Ondrea 500mg Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Ondrea 500mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Ondrea 500mg Capsule may be needed. Please consult your doctor.
Regular monitoring of kidney function test and some blood tests may be advised while you are taking this medicine.
Regular monitoring of kidney function test and some blood tests may be advised while you are taking this medicine.
Liver
CAUTION
Ondrea 500mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Ondrea 500mg Capsule may be needed. Please consult your doctor.
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Quick tips
- Take it at the same time every day, either with or without food.
- It is advisable to stay hydrated and drink plenty of fluids while taking Ondrea 500mg Capsule.
- Do not skip any dose and complete the course as suggested by your doctor.
- Use an effective method of birth control to avoid pregnancy while taking this medication.
- Your doctor may get regular blood tests done to monitor your electrolyte levels, liver function, blood cell count in your blood.
- Take it at the same time every day, either with or without food.
- It is advisable to stay hydrated and drink plenty of fluids while taking Ondrea 500mg Capsule.
- Do not skip any dose and complete the course as suggested by your doctor.
- Use an effective method of birth control to avoid pregnancy while taking this medication.
- Your doctor may get regular blood tests done to monitor your electrolyte levels, liver function, blood cell count in your blood.
Fact Box
Chemical Class
Anti Metabolites, {Urea}
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Anticancer-others
Patient concerns
User feedback
What are you using Ondrea Capsule for?
Sickle cell a*
50%
Others
50%
*Sickle cell anemia
How much was the improvement?
Average
100%
What were the side-effects while using Ondrea 500mg Capsule?
Nausea
50%
Loss of appet*
50%
*Loss of appetite
FAQs
How to get relief from diarrhea while on treatment with Ondrea 500mg Capsule?
Food items with soluble fiber can help relieve diarrhea as they help absorb excess fluid from the body. These food items include bananas (ripe), oranges, boiled potatoes, white rice, curd, and oatmeal. Diarrhea can cause dehydration in the body, so drink 8-10 glasses of water to avoid dehydration. You can also have soups and juice frequently to hydrate yourself.
Should I avoid any food and drinks while taking Ondrea 500mg Capsule?
You can continue with your normal diet unless your doctor tells you otherwise. However, it is advisable to sip water regularly to prevent you from becoming dehydrated, eat small, simple but nourishing snacks every few hours rather than large meals, and suck on hard candy or popsicles to prevent nausea and vomiting.
How to cope with tiredness and weakness after starting treatment?
Various things can help you to reduce tiredness and cope with it, for example, gentle exercise. Always consult your doctor before doing any kind of exercise.
Can Ondrea 500mg Capsule be taken during pregnancy?
This treatment may harm a baby developing in the womb. It is important not to become pregnant or father a child while you are having treatment and for at least 6 months afterward. Talk to your doctor about effective contraception before starting the treatment.
Does Ondrea 500mg Capsule cause hair loss?
Yes, while taking this medicine, your hair may become brittle and break. You may also experience patchy hair loss or thinning. These conditions tend to resolve once treatment is stopped. Be gentle when brushing and washing hair to manage hair loss.
I have noticed some changes in my skin after taking Ondrea 500mg Capsule? What should I do?
Use a moisturizer to get relief from rashes, and dry and itchy skin. Avoid direct sunlight, wear protective clothing, and use sunscreen (SPF of more than 15) whenever you step outdoors. Do not go swimming if you have a rash because the chlorine in the water can make it worse. Avoid hot water baths and wear loose and cotton fabric clothes. Your skin will tend to become better once treatment is stopped.
How to relieve constipation during the treatment?
To relieve constipation, include fiber in your diet (fruits and vegetables), drink 8-10 glasses of fluids a day, and keep active. A stool softener (with a doctor's prescription) once or twice a day may prevent constipation. If you do not have a bowel movement for 2-3 days, consult your doctor.
What precautions should I take to reduce the chances of getting infected during treatment with Ondrea 500mg Capsule?
Since Ondrea 500mg Capsule lowers the number of white blood cells and platelets in your blood, it puts you at a risk of getting an infection. In order to prevent, avoid people who have infections. Check with your doctor immediately if you think you may be getting an infection, or if you get a fever, or chills.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1721-22.
- Masters SB. Agents Used in Anemias; Hematopoetic Growth Factors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 578.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 672-75.
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Hydroxyurea. [Updated 2020 Jan 20]. [Accessed 18 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Marketer details
Name: Vhb Life Sciences Inc
Address: 50-AB, Government Industrial Estate, Charkop Naka, Kandivali West , Mumbai - 400067, Maharashtra, India
Country of origin: India
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