Onstart Injection
Prescription Required
Product introduction
Onstart Injection is an antiemetic medicine commonly used to control nausea and vomiting due to certain medical conditions like stomach upset. It is also used to prevent nausea and vomiting caused due to any surgery, cancer drug therapy or radiotherapy.
Onstart Injection will not relieve other side effects associated with cancer treatments. It is given under the supervision of a doctor and may be used alone or with other medications. Your doctor will give you appropriate dose depending on what you are taking it for. It is important that you keep having the injections until your doctor decides it is safe to stop them. After this, your doctor may prescribe tablets instead of the injections.
The most common side effects of taking this medicine include injection site pain, headache, and constipation. These symptoms should disappear when you stop taking the medicine. But, if these side effects bother you or do not go away, consult your doctor who may be able to suggest ways of preventing or reducing them.
Before taking this medicine, tell your doctor if you have heart or liver problems or a blockage in your stomach or intestines. Also, tell your doctor about other drugs you are using, especially medicines to treat epilepsy, heart problems, cancer, and depression. These may affect, or be affected by, this medicine. If you are pregnant or breastfeeding, ask for advice from your healthcare team.
Onstart Injection will not relieve other side effects associated with cancer treatments. It is given under the supervision of a doctor and may be used alone or with other medications. Your doctor will give you appropriate dose depending on what you are taking it for. It is important that you keep having the injections until your doctor decides it is safe to stop them. After this, your doctor may prescribe tablets instead of the injections.
The most common side effects of taking this medicine include injection site pain, headache, and constipation. These symptoms should disappear when you stop taking the medicine. But, if these side effects bother you or do not go away, consult your doctor who may be able to suggest ways of preventing or reducing them.
Before taking this medicine, tell your doctor if you have heart or liver problems or a blockage in your stomach or intestines. Also, tell your doctor about other drugs you are using, especially medicines to treat epilepsy, heart problems, cancer, and depression. These may affect, or be affected by, this medicine. If you are pregnant or breastfeeding, ask for advice from your healthcare team.
Side effects of Onstart Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Onstart
- Injection site pain
- Constipation
- Diarrhea
- Fatigue
- Headache
How to use Onstart Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Onstart Injection works
Onstart Injection is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.
Safety advice
Alcohol
SAFE
Consuming alcohol with Onstart Injection does not cause any harmful side effects.
Pregnancy
SAFE IF PRESCRIBED
Onstart Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Onstart Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
SAFE
Onstart Injection does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Onstart Injection is safe to use in patients with kidney disease. No dose adjustment of Onstart Injection is recommended.
However, inform your doctor if you have an underlying kidney disease. Limited information is available in patients taking this medicine for more than one day.
However, inform your doctor if you have an underlying kidney disease. Limited information is available in patients taking this medicine for more than one day.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Onstart Injection in patients with liver disease. Please consult your doctor.
What if you forget to take Onstart Injection?
If you miss a dose of Onstart Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n
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Quick tips
- You have been prescribed Onstart Injection for prevention of nausea and vomiting caused after surgery or due to chemotherapy and radiotherapy.
- It is given as an injection into veins or as drip under the supervision of a doctor.
- Avoid heavy meals and try eating small nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.
- It may cause an application site reaction like redness, swelling, and pain. Consult with your doctor if it bothers you.
- You have been prescribed Onstart Injection for prevention of nausea and vomiting caused after surgery or due to chemotherapy and radiotherapy.
- Unlike some other nausea medicines, the side effects for Onstart Injection are relatively mild.
- It comes in many different forms that do not need to be swallowed, such as a film that is placed on the tongue or as a dissolving pill.
- It is fast-acting and starts working within 30 minutes.
- If you vomit within one hour of taking a dose, take another dose.
- Avoid heavy meals and try eating small nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.
Fact Box
Chemical Class
Carbazole Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Serotonin 5-HT3 Receptor Antagonists
Interaction with drugs
Taking Onstart with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Fluconazole with Ondansetron.
Concomitant use may affect heart rhythm and can be fatal.
Do not consume Domperidone with Ondansetron.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Hydroxyzine with Ondansetron.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Voriconazole with Ondansetron.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Voriconazole with Ondansetron.
Patient concerns
FAQs
How quickly does Onstart Injection work?
Onstart Injection starts working within half an hour to 2 hours. It dissolves rapidly into the bloodstream and starts showing its effect.
What are the side effects of Onstart Injection?
The most common side effects of Onstart Injection are constipation, diarrhea, fatigue and headache. However, these are usually not bothersome and resolve on their own after some time. Consult your doctor if these persist or worry you.
Is Onstart Injection a steroid?
No, Onstart Injection is an antiemetic and not a steroid. Onstart Injection is a selective 5-HT3 receptor antagonist. It is prescribed for the prevention and treatment of nausea and vomiting which is commonly observed after surgery or due to cancer chemotherapy.
Does Onstart Injection work for seasickness?
No, Onstart Injection does not work for seasickness. This is because Onstart Injection has very little effect on the nausea associated with motion sickness.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1341-42.
- Katzung BG. Histamine, Serotonin, & the Ergot Alkaloids. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 285
- MedlinePlus. Ondansetron. [Accessed 28 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Ondansetron. [Updated 2019 Feb 7]. [Accessed 20 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
Marketer details
Name: Punjab Formulations Ltd
Address: 339, LAXMI PLAZA, LAXMI INDUSTRIAL ESTATE, NEW LINK ROAD, ANDHERI (WEST) MUMBAI MH 400053 IN , - , .
Country of origin: India
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₹11.3
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2.0 ml in 1 vial
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