Opigrel 75mg Tablet is an antiplatelet medicine or a blood thinner that helps to prevent the formation of harmful blood clots in your blood vessels. This helps to lower the chances of you getting a heart attack or stroke. It is a widely used medicine for heart protection.

Opigrel 75mg Tablet is prescribed to people at high risk of heart disease. This includes people with peripheral vascular disease (blood circulation problems due to narrowing of blood vessels), recent heart attack or stroke, irregular heartbeats, and those who have undergone certain heart procedures like stenting. It is also used in combination with some other medicines for the treatment of heart attack and some types of heart-related chest pain (unstable angina).

This medicine may be taken with or without food and should be taken at the same time each day. It is important to keep taking this medicine even if you feel well. If you stop taking this medicine, it may increase your chance of having a heart attack or stroke.

The most common side effect seen with this medicine is bleeding. This may be in the form of bruising, nose bleeds, blood in urine or stools (black-colored stools), or heavier periods than usual in women. If you cut or injure yourself, it may take longer than usual for the bleeding to stop. Such episodes of bleeding are usually mild and resolve on their own. However, you should consult your doctor straight away if the bleeding persists or worries you.

This medicine is not suitable for some people. Do not take it if you are bleeding from anywhere in the body such as a stomach ulcer or bleeding within the brain. Before taking it, you should let your doctor know if you have ever had a problem with your blood not clotting properly or if you have recently had a serious injury or surgery. This medicine may need to be stopped temporarily before planned surgery or dental treatment.

Uses of Opigrel Tablet

Heart attack
Peripheral vascular disease
Unstable angina
Prevention of heart attack and stroke

Side effects of Opigrel Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Opigrel

Bruise
Diarrhea
Hematoma
Abdominal pain
Nosebleeds
Gastrointestinal bleeding
Dyspepsia

How to use Opigrel Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Opigrel 75mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Opigrel Tablet works

Opigrel 75mg Tablet is an antiplatelet medication. It works by preventing platelets from sticking together, thereby decreasing the formation of harmful blood clots. This lowers the chance of heart attack or stroke.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Opigrel 75mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Opigrel 75mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Opigrel 75mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

SAFE

Opigrel 75mg Tablet does not usually affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Opigrel 75mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Opigrel 75mg Tablet is recommended.

Liver

SAFE IF PRESCRIBED

Opigrel 75mg Tablet is safe to use in patients with liver disease. No dose adjustment of Opigrel 75mg Tablet is recommended.

What if you forget to take Opigrel Tablet?

If you miss a dose of Opigrel 75mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Opigrel 75mg Tablet

₹3.1/Tablet

Clopilet Tablet

Sun Pharmaceutical Industries Ltd

₹7.27/tablet

135% costlier

Clopicare 75mg Tablet

Hochest Biotech India

₹5.62/tablet

81% costlier

Clopiclot 75mg Tablet

Adrena Healthcare Pvt Ltd

₹4.56/tablet

47% costlier

Clopit 75mg Tablet

Taurus Laboratories Pvt Ltd

₹6.79/tablet

119% costlier

Clopirest 75 Tablet

Matias Healthcare Pvt Ltd

₹6.69/tablet

116% costlier

View all substitutes

Quick tips

For best results, take it at the same time every day.
Opigrel 75mg Tablet increases your risk of bleeding. Be careful while shaving, using sharp objects, or cutting fingernails or toenails.
Do not discontinue using the medicine without consulting your doctor as this may increase your chances of having another heart attack or stroke.
If you are scheduled to undergo a surgery or dental treatment, you may be asked to stop taking Opigrel 75mg Tablet temporarily.

Fact Box

Chemical Class

Alpha amino acid esters

Habit Forming

Therapeutic Class

BLOOD RELATED

Action Class

P2Y12-ADP Receptor Antagonists

Interaction with drugs

Taking Opigrel with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Fluconazole (Oral Route) Severe

Fluconazole may reduce blood levels and efficacy of the active form of Clopidogrel. Do not consume Clopidogrel with Fluconazole.

Fluconazole (Injection Route) Severe

Fluconazole may reduce blood levels and efficacy of the active form of Clopidogrel. Do not consume Clopidogrel with Fluconazole.

Atazanavir (Oral Route) Severe

Atazanavir may reduce blood levels of active form of Clopidogrel. Do not consume Clopidogrel with Atazanavir.

Darunavir (Oral Route) Severe

Darunavir may reduce blood levels of active form of Clopidogrel. Do not consume Clopidogrel with Darunavir.

Fluvoxamine (Oral Route) Severe

Concurrent use may increase the risk of bleeding. If concurrent use is essential, watch out for bleeding and consult your doctor immediately. They may adjust the doses as per the ... More

View all drug interactions

Patient concerns

What is heart attack? When heart attack coming?

Dr. Nabajit Talukdar

Cardiology

Related to chest pain angina commonly

mild heart attack few weeks ago. Coronary Artery Disease - Unstable Angina, Anterior Lateral Wall Ischemia, Mild LV Dysfunctional(EF-52%), Mild to Moderate AR, Mild PAH, TROP - I Positive

Dr. Deepak Kumar Soni

Ayurveda

Hi Kindly consult to Ayurvedic doctor at your local city area , face to face consult is needed.

What are the trip t normal and high values What should be thresholds for ' no heart'' attack', minor attack and heart attack

Dr. Ila Jain Khandelwal

Pathology

Hello sir. Thank you for consulting with us. Trop T is read as either positive or increased or not positive. Positive Trop T level indicates heart attack and negative Trop t usually indicates no heart attack. Even in minor heart attack, Trop T is positive.

What are the health problems that one can get if the one keeps on taking a chronic stress and depression over a prolonged period of time. Seing that im experiencing some symtoms like chronic head ache, nausea, heart pain, gastrointiatinal bleeding, urine in the blood, sleep deprivation, weight loss due to exyreme thinking. Pls advise me in this connection

Dr. Pushkar Mani

Physician

Heart attack, Kidney problems all u can get

FAQs

What is Opigrel 75mg Tablet used for?

Opigrel 75mg Tablet is used to prevent formation of blood clots, thus reducing the risk of heart attacks or stroke. It facilitates smooth circulation of blood in the body by reducing the ability of the platelets to stick together, that could otherwise lead to formation of harmful clots in hardened blood vessels.

Is Opigrel 75mg Tablet a blood thinner?

Yes, Opigrel 75mg Tablet is an antiplatelet medicine which is also known as a blood thinner. It makes your blood flow more easily through your blood vessels and prevents formation of harmful blood clots. This lowers your chances of heart attack or stroke.

When should you take Opigrel 75mg Tablet?

You should take Opigrel 75mg Tablet exactly as prescribed by the doctor. You can take it with or without food, at any time of the day. However, it is important to take it regularly at the same time each day for best results. This will also help you to remember to take it daily.

Does Opigrel 75mg Tablet affect blood pressure?

Yes, Opigrel 75mg Tablet may rarely cause a decrease in blood pressure as a side effect. However, this is very rare and does not affect everyone. Consult your doctor if you feel dizzy, lightheaded, weak or have a blurred vision. These are signs and symptoms of low blood pressure and therefore, you should contact your doctor immediately.

Who should not take Opigrel 75mg Tablet?

Opigrel 75mg Tablet is not recommended for people who are allergic to it, have severe liver disease, have stomach ulcers, bleeding in the brain, or have a bleeding disorder known as hemophilia (disease in which blood does not clot normally).

Can omeprazole be taken along with Opigrel 75mg Tablet?

Omeprazole ( a proton pump inhibitor or PPI used to treat and prevent indigestion) may interfere with the working of Opigrel 75mg Tablet and reduce the effect of Opigrel 75mg Tablet. Your doctor may prescribe an alternate PPI like lansoprazole, if you suffer from indigestion or if they judge that it would be beneficial to you. You should let your doctor know about all the medicines that have been prescribed to you before starting Opigrel 75mg Tablet. Always consult your doctor before taking any medicine.

What will happen if I stop taking Opigrel 75mg Tablet?

If you stop taking Opigrel 75mg Tablet suddenly, your chances of heart attack or stroke may increase. These conditions can be fatal. Do not stop taking it without talking to your doctor, otherwise your condition may worsen. Continue taking Opigrel 75mg Tablet for as long as prescribed by your doctor to get maximum benefit.

How long does it take Opigrel 75mg Tablet to start working? How long do I need to take it?

Opigrel 75mg Tablet starts working within 2 hours of taking it. Continue taking it as long as your doctor has advised you. You may have to take it for a few weeks or months, or you may have to take it for the rest of your life.

What are the side effects of taking Opigrel 75mg Tablet?

The most common side effect of Opigrel 75mg Tablet is bleeding. This may lead to bruising on the skin, nosebleeds, blood in the urine or stools (black tarry stools), or heavier periods than usual in females. Rarely, bleeding may also occur in the head, eyes, lungs, or joints and may even be severe. In case you have a minor injury, such as a small cut while shaving, bleeding may take longer than usual to stop. Get emergency medical help if the bleeding is profuse, does not stop on it’s own, or bothers you. Other side effects of Opigrel 75mg Tablet that may be seen occasionally in some people include diarrhea, abdominal pain, indigestion or heartburn. Please consult your doctor if any of these side effects persist or worry you.

Can I take alcohol with Opigrel 75mg Tablet?

Yes, you can take alcohol with Opigrel 75mg Tablet. However, excessive intake of alcohol should be avoided as it can irritate the inner lining of the stomach and this increases the risk of developing a stomach ulcer later.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 869-70.
Zehnder JL. Drugs Used in Disorders of Coagulation. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 598-99.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 304-305.
Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 245-48.
Clopidogrel bisulfate. New York, New York: Bristol-Myers Squibb/Sanofi Pharmaceuticals Partnership; 2006. [Accessed 15 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). Clopidogrel. [Accessed 15 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006. Clopidogrel. [Updated 2019 Jun 3]. [Accessed 17 Jun. 2023] (online) Available from:
Clopidogrel [Summary of Product Characteristics]. Rue de la Vierge, France: Sanofi Winthrop Industrie; 2022. [Accessed 17 Jun. 2023] (online) Available from:

Marketer details

Name: Henry Pharmaceuticals

Address: Devkinandan Basement , Tekdi, Ulhasnagar 1, Mumbai CST Area, Mumbai-400001, Maharashtra, India

Country of origin: India

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