Oreflo-Plus Tablet MR is a combination of two medicines that work in different ways to treat men with an enlarged prostate gland. It helps to relieve symptoms such as difficulty urinating or needing to go to the toilet more often. It is not used to prevent prostate cancer.

Oreflo-Plus Tablet MR may be taken with or without food but it should be taken at the same time each day. Your doctor will prescribe the dose most suitable for you. To gain the most benefit and to treat your symptoms effectively, you should not miss doses, even if you feel well. It may take up to 4 weeks to notice an improvement in the symptoms but keep taking them regularly. Tell your doctor if your symptoms do not improve after 4 weeks or if they get worse.

The most common side effects of this medicine include impotence, decreased libido, breast pain, and ejaculation disorder. If these side effects worry you or do not go away, call your doctor for advice. You may also feel dizzy or drowsy. These risks are higher when you first start taking this drug. Remember, your doctor has given you this medicine because the benefits are greater than the risks of the side effects.

Oreflo-Plus Tablet MR should not be taken by women or children. Before taking it, tell your doctor if you have low blood pressure or liver or kidney disease. This medicine may not be suitable. It can also affect, or be affected by, other drugs. So let your doctor know all the other medicines you are taking. You may be advised to wear a condom during sex if your partner is or may be pregnant. Your doctor may recommend getting your blood pressure checked frequently. Avoid drinking alcohol as it can cause excessive dizziness with this medicine.

Uses of Oreflo-Plus Tablet MR

Treatment of Benign prostatic hyperplasia

Benefits of Oreflo-Plus Tablet MR

In Treatment of Benign prostatic hyperplasia

When your prostate gland becomes enlarged it can cause urinary problems such as difficulty passing urine and a need to go to the toilet frequently or urgently. It can also cause urine flow to be slower. If not treated, there is a risk that your urine flow will be completely blocked. Oreflo-Plus Tablet MR is a combination of two medicines: dutasteride and tamsulosin. Dutasteride reduces the size of your prostate by blocking the production of a hormone which causes it to grow. Tamsulosin works by relaxing muscles in the bladder and prostate. Together they can rapidly relieve the symptoms and make it easier for you to urinate. However, it may take up to 6 months to notice the full benefit. Take this medicine exactly as prescribed for maximum benefits.

Side effects of Oreflo-Plus Tablet MR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Oreflo-Plus

Impotence
Decreased libido
Ejaculation disorder
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Breast enlargement in male
Breast tenderness in male
Dizziness

How to use Oreflo-Plus Tablet MR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Oreflo-Plus Tablet MR may be taken with or without food, but it is better to take it at a fixed time.

How Oreflo-Plus Tablet MR works

Oreflo-Plus Tablet MR is a combination of two medicines: Tamsulosin and Dutasteride, which relieves the symptoms of benign prostatic hyperplasia. Tamsulosin is an alpha-blocker. It works by relaxing the muscle around the bladder exit and prostate gland so as to allow easy passage of urine. Dutasteride is a 5-alpha-reductase inhibitor which helps in shrinking the prostate gland by decreasing the level of the hormone which helps the prostate gland grow.

Safety advice

Alcohol

UNSAFE

Oreflo-Plus Tablet MR may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Oreflo-Plus Tablet MR during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Oreflo-Plus Tablet MR during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Oreflo-Plus Tablet MR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Oreflo-Plus Tablet MR in patients with kidney disease. Please consult your doctor.

Liver

CAUTION

Oreflo-Plus Tablet MR should be used with caution in patients with liver disease. Dose adjustment of Oreflo-Plus Tablet MR may be needed. Please consult your doctor.
Use of Oreflo-Plus Tablet MR is not recommended in patients with severe liver disease.

What if you forget to take Oreflo-Plus Tablet MR?

If you miss a dose of Oreflo-Plus Tablet MR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Oreflo-Plus Tablet MR

₹16.2/Tablet MR

Urimax D Tablet MR

Cipla Ltd

₹38.13/tablet mr

135% costlier

Veltam Plus Tablet MR

Intas Pharmaceuticals Ltd

₹37.8/tablet mr

133% costlier

Urimax D Tablet MR

Cipla Ltd

₹36.6/tablet mr

126% costlier

Tamdosin D Tablet MR

Corona Remedies Pvt Ltd

₹17.53/tablet mr

8% costlier

Uritin-D Tablet MR

Overseas Healthcare Pvt Ltd

₹35/tablet mr

116% costlier

View all substitutes

Quick tips

You have been prescribed Oreflo-Plus Tablet MR to relieve the symptoms of benign prostatic hyperplasia (BPH).
Take it approximately 30 minutes after the same meal each day.
Oreflo-Plus Tablet MR may cause dizziness or blurring of vision. Do not drive or do anything requiring concentration until you know how it affects you.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
If you are scheduled to undergo an eye surgery due to cataract or glaucoma, inform your eye doctor about the usage of Oreflo-Plus Tablet MR.
It may cause difficulty achieving or maintaining an erection (impotence), decreased sex drive, and ejaculation disorders such as decreased amount of semen produced or decreased sperm count.
Do not donate blood for 6 months after taking the last dose of Oreflo-Plus Tablet MR.

Fact Box

Habit Forming

Therapeutic Class

UROLOGY

Patient concerns

I had recently undergone left humerus plating surgery and i was told to take setfrac plus tablet The problem is setfrac plus tablet is not available in my town so can u please sugeat the substitute tablet to setfrac plus?????

Dr. Rohit Chakor

Orthopaedics

You see the content of the tablet and ask for it

Can i take purtia tablet instead of purtia plus

Dr. Akshat Goel

Orthopaedics

Please refer to a General Physician

FAQs

Is Oreflo-Plus Tablet MR effective?

Oreflo-Plus Tablet MR is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Oreflo-Plus Tablet MR too early, the symptoms may return or worsen.

Can the use of Oreflo-Plus Tablet MR cause dizziness?

Yes, the use of Oreflo-Plus Tablet MR can cause dizziness. Oreflo-Plus Tablet MR contains a combination of Tamsulosin and Dutasteride. Tamsulosin can cause a sudden fall in blood pressure while changing posture from lying to sitting or standing (orthostatic hypotension). This sudden fall in blood pressure can cause dizziness, lightheadedness, fainting, sensation of spinning and vertigo. If you feel dizzy or lightheaded, do not drive or use any machines. It is better to rest for some time and resume once you feel better.

What are the cautions associated with the use of Oreflo-Plus Tablet MR?

The use of Oreflo-Plus Tablet MR is considered to be harmful for men under the age of 18 years as it may affect the normal development of the male reproductive tract. The use of this medicine is also considered to be harmful for patients with any known allergy to any of the components of this medicine and in women who are pregnant or of childbearing potential. Along with that, it is important to keep in mind that pregnant women should not even handle Oreflo-Plus Tablet MR as the medicine may get absorbed through the skin and cause harm to the fetus.

Is Oreflo-Plus Tablet MR safe?

Oreflo-Plus Tablet MR is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

Can I take a higher than the recommended dose of this medicine?

No, Oreflo-Plus Tablet MR should be taken in the recommended dose only. An overdose of Oreflo-Plus Tablet MR can increase the risks of side effects. Always take your medicines according to the dose and duration prescribed by your doctor.

What is the storage condition for Oreflo-Plus Tablet MR?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Can the use of Oreflo-Plus Tablet MR cause ejaculation problems?

Retrograde ejaculation (semen does not leave the body, instead goes into the bladder) and ejaculation failure (reduced or absent ejaculation volume) are common problems associated with the use of Oreflo-Plus Tablet MR. But this is harmless and more commonly seen when the medicine is consumed in high doses.

Can the use of Oreflo-Plus Tablet MR cause priapism (persistent painful penile erection unrelated to sexual activity)?

Yes, the use of Oreflo-Plus Tablet MR can cause priapism (painful penile erection). It is a serious but rare side effect associated with the use of this medicine. However, in some cases, it can lead to permanent impotence if not treated immediately.

Can the use of Oreflo-Plus Tablet MR have any impact on my cataract surgery?

Use of Oreflo-Plus Tablet MR can cause floppy eye syndrome. In this, the muscles of the iris become floppy and the pupil constricts unexpectedly during cataract surgery. So, when the eye surgeon actually needs a dilated pupil, the pupil constricts unexpectedly. This restricts the field of surgery because of which the surgical outcomes can get affected. Inform your eye doctor (ophthalmologist) if you are taking this medicine or in case you have used this medicine in the last 9 months.

Apart from taking medicines, what should I do to manage my prostate symptoms?

Simple lifestyle changes can help you manage your prostate symptoms better. Try to urinate when you first get the urge. However, take care not to strain or push while urinating. Avoid drinking fluids (especially alcohol, caffeine) a few hours before bedtime or going out. You should also avoid medicines which tend to worsen urinary symptoms like some over-the-counter medicines for cold and cough.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

CiplaMed. Tamsulosin hydrochloride + Dutasteride [Accessed 25 Apr. 2019] (online) Available from:

Marketer details

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The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.