Orflam SP 100mg/325mg/15mg Tablet is a combination medicine that helps in relieving pain. It works by blocking the release of certain chemical messengers that cause pain, inflammation, and fever in various conditions. It also promotes healing at the site of inflammation.

Orflam SP 100mg/325mg/15mg Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.

The most common side effects of this medicine include nausea, vomiting, diarrhea, stomach pain, increased liver enzymes, and heartburn. If any of these side effects bother you or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the side effects.

Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.

Note: As per the Ministry of Health and Family Welfare, Orflam SP 100mg/325mg/15mg Tablet is banned for children under 12 years of age.

Uses of Orflam SP Tablet

Pain relief

Side effects of Orflam SP Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Orflam SP

Nausea
Vomiting
Diarrhea
Stomach pain
Increased liver enzymes
Heartburn

How to use Orflam SP Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Orflam SP 100mg/325mg/15mg Tablet is to be taken with food.

How Orflam SP Tablet works

Orflam SP 100mg/325mg/15mg Tablet is a combination of three medicines: Nimesulide, Paracetamol and Serratiopeptidase. Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) and Paracetamol is an antipyretic (fever reducer). They work by blocking the release of certain chemical messengers in the brain that cause pain and fever. Serratiopeptidase is an enzyme which works by breaking down abnormal proteins at the site of inflammation, and promotes healing.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Orflam SP 100mg/325mg/15mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Orflam SP 100mg/325mg/15mg Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Orflam SP 100mg/325mg/15mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Orflam SP 100mg/325mg/15mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CAUTION

Orflam SP 100mg/325mg/15mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Orflam SP 100mg/325mg/15mg Tablet may be needed. Please consult your doctor.
Use of Orflam SP 100mg/325mg/15mg Tablet is not recommended in patients with severe kidney disease.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Orflam SP 100mg/325mg/15mg Tablet in patients with liver disease. Please consult your doctor.

What if you forget to take Orflam SP Tablet?

If you miss a dose of Orflam SP 100mg/325mg/15mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Orflam SP 100mg/325mg/15mg Tablet

₹6.47/Tablet

Nimdase-P Tablet

Obsurge Biotech Ltd

₹11.9/tablet

84% costlier

Nimiz-SP Tablet

Hilbert Healthcare

₹8.73/tablet

35% costlier

Sumoflam Tablet

Alkem Laboratories Ltd

₹14.47/tablet

124% costlier

Avernim SP 100mg/325mg/15mg Tablet

Altrawell Biotech Pvt Ltd

₹8.53/tablet

32% costlier

Shuma SP 100mg/325mg/15mg Tablet

Loremchem Pharmaceutical

₹9.21/tablet

42% costlier

View all substitutes

Quick tips

You have been prescribed this combination medicine for relieving pain and inflammation.
Take it with food to avoid getting an upset stomach.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how Orflam SP 100mg/325mg/15mg Tablet affects you.
Avoid consuming alcohol when taking Orflam SP 100mg/325mg/15mg Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first.
You have been prescribed this combination medicine for relieving pain and inflammation.
Take it with food to avoid getting an upset stomach.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how Orflam SP 100mg/325mg/15mg Tablet affects you.
Avoid consuming alcohol when taking Orflam SP 100mg/325mg/15mg Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Patient concerns

One of my teeth is sensitive. It some times pains

Dr. Abhijit Gambhir

Dental Surgery

sensitivity has many causative factors for relief of pain you can take pain killers it will give temporary relief

fever and 2 months pregnant can take combiflan

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

No take Crocin for pain relief

FAQs

Can I stop taking Orflam SP 100mg/325mg/15mg Tablet when my pain is relieved?

Orflam SP 100mg/325mg/15mg Tablet is usually used for short-term pain relief and can be discontinued if there is no pain. However, it should be continued if advised by the doctor.

Can the use of Orflam SP 100mg/325mg/15mg Tablet cause damage to the liver?

Orflam SP 100mg/325mg/15mg Tablet contains nimesulide and paracetamol, and both these medicines are known to cause harm to the liver especially in doses above the recommended level. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with underlying liver disease.

Can I take a higher than the recommended dose of Orflam SP 100mg/325mg/15mg Tablet?

No, taking a higher than the recommended dose of Orflam SP 100mg/325mg/15mg Tablet can lead to increased chances of side effects. If the recommended dosage does not relieve your symptoms or you experience increased severity of pain, please consult your doctor for re-evaluation.

What are the instructions for the storage and disposal of Orflam SP 100mg/325mg/15mg Tablet?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Top Rheumatologists

4.9 ★

5 ★

4.7 ★

MBBS, DNB, MD, Fellowship, Fellowship

4.7 ★

Dr. Indrajit Agrawal

MBBS, MD, Fellowship

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

European Medicine Agency. Nimesulide; 2004. [Accessed 02 Apr. 2019] (online) Available from:
Bhagat S, Agarwal M, Roy V. Serratiopeptidase: A systematic review of the existing evidence. Int J Surg. 2013;11(3):209-17. [Accessed 02 Apr. 2019] (online) Available from:
ScienceDirect. Nimesulide. [Accessed 02 Apr. 2019] (online) Available from:
ScienceDirect. Paracetamol. [Accessed 02 Apr. 2019] (online) Available from:
PubChem. Serratiopeptidase. [Accessed 02 Apr. 2019] (online) Available from:

Marketer details

Name: Orlife Healthcare

Address: Plot No-315, 1st Floor, Industrial Area, Phase-II, Panchkula Haryana

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.