Orif 3 Tablet
Prescription Required
Product introduction
Orif 3 Tablet is a combination medicine used in the treatment of tuberculosis. It prevents the growth of the microorganisms that cause the infection.
Orif 3 Tablet is a prescription medicine and it is to be taken it as suggested by the doctor. It should be taken in an empty stomach and take it at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine. The medicine may take some to show its effects on the symptoms. However, it is advised to consult the doctor if you feel an aggravation of the condition or if your condition does not improve.
Some common side effects of this medicine are nausea, vomiting, fever, dark-colored urine, sweating, increased saliva, etc. To cope up with the side effects, you should drink plenty of water. If any of the side effects get aggravated, you must consult your doctor immediately. Generally, serious side effects are rare. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.
Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Patients with liver and kidney ailments must take this medicine with proper consultation and caution. Pregnant or breastfeeding women should also consult with the doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. During the treatment, you must take adequate rest and eat a healthy diet for a faster recovery. While on the medication, your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.
Orif 3 Tablet is a prescription medicine and it is to be taken it as suggested by the doctor. It should be taken in an empty stomach and take it at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine. The medicine may take some to show its effects on the symptoms. However, it is advised to consult the doctor if you feel an aggravation of the condition or if your condition does not improve.
Some common side effects of this medicine are nausea, vomiting, fever, dark-colored urine, sweating, increased saliva, etc. To cope up with the side effects, you should drink plenty of water. If any of the side effects get aggravated, you must consult your doctor immediately. Generally, serious side effects are rare. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.
Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Patients with liver and kidney ailments must take this medicine with proper consultation and caution. Pregnant or breastfeeding women should also consult with the doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. During the treatment, you must take adequate rest and eat a healthy diet for a faster recovery. While on the medication, your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.
Uses of Orif Tablet
Benefits of Orif Tablet
In Tuberculosis (TB)
Orif 3 Tablet is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It kills as well as stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.
Side effects of Orif Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Orif
- Nausea
- Vomiting
- Peripheral neuropathy (tingling and numbness of feet and hand)
- Abdominal pain
- Skin rash
- Hepatitis (viral infection of liver)
- Lethargy
- Low blood platelets
- Thrombocytopenic purpura
- Cutaneous reactions
How to use Orif Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Orif 3 Tablet is to be taken empty stomach.
Avoid Orif 3 Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.
Avoid Orif 3 Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.
How Orif Tablet works
Orif 3 Tablet is a combination of three medicines: Isoniazid, Pyrazinamide and Rifampicin which treat tuberculosis. Isoniazid prevents the TB bacteria from forming their own protective covering while Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by these bacteria to make essential proteins and to reproduce. Together, they kill the bacteria and eradicate the infection. Pyrazinamide, on the other hand works by slowing the growth of these bacteria.
Safety advice
Alcohol
UNSAFE
Consuming alcohol while taking Orif 3 Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
CONSULT YOUR DOCTOR
Orif 3 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Orif 3 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Orif 3 Tablet may cause side effects which could affect your ability to drive.
You may feel dizzy or faint, have problems with vision or have other side effects that could affect your ability to drive.
You may feel dizzy or faint, have problems with vision or have other side effects that could affect your ability to drive.
Kidney
CAUTION
Orif 3 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Orif 3 Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Orif 3 Tablet should be used with caution in patients with liver disease. Dose adjustment of Orif 3 Tablet may be needed. Please consult your doctor.
Regular monitoring of liver function tests is advised before and after the start of the treatment.
Regular monitoring of liver function tests is advised before and after the start of the treatment.
What if you forget to take Orif Tablet?
If you miss a dose of Orif 3 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Orif 3 Tablet
₹2.67/Tablet
Tibizim Forte Tablet
Medirose drug & pharma
₹4.54/tablet
70% costlier
T Kox Tablet
Aan Pharma Pvt Ltd
₹4.75/tablet
78% costlier
Rinex Z Tablet
Hamax Pharmaceuticals
₹3.52/tablet
32% costlier
Rifacil 3 Tablet
Mediwin Pharmaceuticals
₹4.75/tablet
78% costlier
Quick tips
- Orif 3 Tablet should be taken on an empty stomach but at the same time every day.
- Do not skip any doses and finish the full course of treatment even if you feel better.
- It may cause dizziness. Don't drive or do anything that requires mental focus until you know how Orif 3 Tablet affects you.
- Avoid drinking alcohol while taking this medicine as this may increase the risk of side effects on the liver.
- Avoid taking hormone-based birth control methods as Orif 3 Tablet may decrease their effectiveness.
- Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.
Fact Box
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Patient concerns
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: The McGraw-Hill Companies, Inc.; 2011. [Accessed 09 Apr. 2019] (online) Available from:
- Drugs.com. Pyrazinamide. [Accessed 09 Apr. 2019] (online) Available from:
- Drugs.com. Rifampicin. [Accessed 09 Apr. 2019] (online) Available from:
Marketer details
Name: Osho Pharma Pvt Ltd
Address: Plot No.2404, Phase IV, GIDC Estate, Vatva, Ahmedabad-382445 (Gujarat).
Country of origin: India
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