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Orpime 500mg Injection

Prescription Required

Product introduction

Orpime 500mg Injection is an antibiotic that fights bacteria. It is used to treat severe bacterial infections of the skin, lungs, stomach, urinary tract, and blood. It works by killing the bacteria that cause these problems. However, it will not treat a viral infection.

Orpime 500mg Injection is commonly used to treat critically ill patients admitted to the hospital. This medicine is given by drip or by direct injection into a vein under the supervision of a doctor or a nurse. The dose will depend on what type of infection you have, where it is in the body, and how serious it is. You should keep taking the injection for as long as you are prescribed, even if your symptoms quickly improve. If you stop taking it too early, the infection may return or worsen.


Common side effects of Orpime 500mg Injection include rash, itching, nausea, vomiting, headache, fever, diarrhea, or local redness and swelling at the site of injection. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or do not go away.


Before starting treatment with this medicine, you should tell your doctor if you have any liver or kidney problems or if you are allergic to any antibiotics. While using it, your doctor may advise blood tests to monitor your kidney function. This medicine is generally regarded as safe to use in pregnancy and breastfeeding if prescribed by your doctor.


Uses of Orpime Injection

  • Treatment of Severe bacterial infections

Benefits of Orpime Injection

In Treatment of Severe bacterial infections

Orpime 500mg Injection works by killing bacteria, which can cause serious infections. It is used to treat many different types of bacterial infections, such as infections of the lungs (pneumonia) and the urinary tract. It is given by a doctor or nurse into a vein and should not be self-administered. Continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and the infection does not return.

Side effects of Orpime Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Orpime

  • Injection site reactions (pain, swelling, redness)
  • Nausea
  • Vomiting
  • Headache
  • Diarrhea
  • Skin rash
  • Increased liver enzymes
  • Positive Coombs test
  • Increased prothrombin time
  • Decreased phosphate level in blood
  • Increased partial thromboplastin time (PTT)
  • Itching

How to use Orpime Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Orpime Injection works

Orpime 500mg Injection is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall), which is needed for them to survive. It weakens the cell wall and makes the bacteria break apart and die. Orpime 500mg Injection works against many different types of bacteria. Orpime 500mg Injection is a broad-spectrum cephalosporin, which means it can treat a wide range of serious infections.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Orpime 500mg Injection. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Orpime 500mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
CAUTION
Orpime 500mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Avoid prolonged use of Orpime 500mg Injection, since it may have possible effects such as rash and diarrhea.
Driving
CONSULT YOUR DOCTOR
It is not known whether Orpime 500mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Orpime 500mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Orpime 500mg Injection may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Orpime 500mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Orpime 500mg Injection may not be needed in these patients. Please consult your doctor.

What if you forget to take Orpime Injection?

If you missed a dose of Orpime 500mg Injection, consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Orpime 500mg Injection
₹92.5/Injection
C Pime 500mg Injection
Emcure Pharmaceuticals Ltd
₹120.62/injection
26% costlier
Biopime 500mg Injection
Biochem Pharmaceutical Industries
₹69.17/injection
28% cheaper
Pripime 500mg Injection
Pride Healthcare
₹124.5/injection
30% costlier
Calpime 500mg Injection
H & I Critical Care
₹126.5/injection
33% costlier
Maxicef 500mg Injection
Aristo Pharmaceuticals Pvt Ltd
₹89.46/injection
6% cheaper

Quick tips

  • Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection come back and harder to treat.
  • Discontinue Orpime 500mg Injection and inform your doctor immediately if you get a rash, itchy skin, swelling of your face and mouth, or difficulty breathing.
  • Diarrhea may occur as a side effect, but it should only stop when your course is completed. Inform your doctor if it does not stop or if you find blood in your stools.

Fact Box

Chemical Class
Broad-spectrum {Third & fourth generation cephalosporins)
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Fourth-Generation Cephalosporins

Interaction with drugs

Taking Orpime with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Purified Vi Polysaccharide Typhoid Vaccine with Cefepime. If Purified Vi Polysaccharide Typhoid Vaccine is essential, ensure a gap of at least 3 days after discontin... More
Do not consume Cholera Vaccine (Inactivated) two weeks before and at least 10 days after consuming Cefepime. Please consult your doctor. Cefepime may reduce the efficacy of Cholera... More
Your doctor may monitor your kidney function regularly. Concurrent use may increase the risk of kidney damage.
Your doctor may monitor your kidney function regularly. Concurrent use may increase the risk of kidney damage.
Your doctor may monitor your kidney function regularly. Concurrent use may increase the risk of kidney damage.

Patient concerns

Scar on face due to bacterial infections
Dr. Atul Jain
Dermatology
Pic is not clear, plz visit for proper opinion
I have a history of recurring yeast and bacterial vaginosis infections.
Dr. Sonu Balhara Ahlawat
Obstetrics and Gynaecology
Tab metrogyl 500 mg twice a day x 5 days and tab fluconazole 150 mg three doses alternate days

FAQs

Can the use of Orpime 500mg Injection cause diarrhea?

Yes, the use of Orpime 500mg Injection can cause diarrhea. It is an antibiotic that kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach and intestines and causes diarrhea. If diarrhea persists, talk to your doctor about it.

What if I don't get better after using Orpime 500mg Injection?

Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform the doctor if your symptoms are getting worse while using this medicine.
Related lab tests

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 222.
  2. Cefepime [Prescribing Information]. Deerfield, IL: Baxter Healthcare Corporation; 2016. [Accessed 29 Mar. 2019] (online) Available from: External Link
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from: External Link
  4. Cefepime [Prescribing Information]. Deerfield, IL: Baxter Healthcare Corporation; 2020. [Accessed 18 Feb. 2025] (online) Available from: External Link
  5. Cefepime [Prescribing Information]. Deerfield, IL: Baxter Healthcare Corporation; 2024. [Accessed 18 Feb. 2025] (online) Available from: External Link
  6. Cefepime [Summary of Product Characteristics]. Gujarat, India: Inject Care Parenterals Pvt. Ltd.; 2023. [Accessed 18 Feb. 2025] (online) Available from: External Link

Marketer details

Name: Orchid Chemicals & Pharmaceuticals Ltd
Address: Orchid Towers', #313, Valluvar Kottam High Road, Nungambakkam, Chennai - 600 034, Tamil Nadu, India
Country of origin: India

NOT FOR SALE
We do not facilitate sale of this product at present

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