Osrise PTH Injection is a man-made version of parathyroid hormone used to treat men and postmenopausal women who have severe osteoporosis with a high risk of fractures. It works by stimulating new bone formation, which improves bone density and decreases the risk of spinal fractures.
Osrise PTH Injection should be injected under the skin or given by a healthcare professional. You should use it regularly and at the same time each day to get the maximum benefit from it. Usually, it is recommended to take it for a maximum period of 2 years. However, follow the doctor’s advice and complete the course even if you feel better. It should be stored in the refrigerator at a temperature of 2°C to 8°C.
Some common side effects of this medicine include joint pain, injection site reactions (such as pain, swelling, and redness) and leg cramps. consult with your doctor if any of these bother you or do not go away.
Before taking this medicine, let your doctor know if you have kidney stones or any other kidney problems, as it can cause an increase in the amount of calcium in blood or urine. Pregnant and breastfeeding mothers should also consult with their doctors before taking this medicine. Your doctor may advise a bone scan to monitor the progress of your treatment.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Osrise PTH
Joint pain
Injection site reactions (pain, swelling, redness)
Nausea
Leg cramps
How to use Osrise PTH Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Osrise PTH Injection works
Osrise PTH Injection is a synthetic form of a natural human hormone called parathyroid hormone (PTH). It works by increasing the number and activity of bone-forming cells (osteoblasts). This strengthens the bones and minimizes the risk of fractures.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Osrise PTH Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Osrise PTH Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Osrise PTH Injection during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Osrise PTH Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Osrise PTH Injection should be used with caution in patients with kidney disease. Dose adjustment of Osrise PTH Injection may be needed. Please consult your doctor. Use of Osrise PTH Injection is not recommended in patients with severe kidney disease.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Osrise PTH Injection in patients with liver disease. Please consult your doctor.
What if you forget to take Osrise PTH Injection?
If you miss a dose of Osrise PTH Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Osrise PTH Injection should be injected every day under the skin (subcutaneous injection) of the thigh or abdomen.
Do not take it for more than 2 years.
You may have low blood pressure and dizziness during the initial few days.
If you feel dizzy (light-headed) after injection, sit or lie down until you feel better.
Tell your doctor immediately if you experience nausea, vomiting, constipation, low energy, or muscle weakness. These may be signs of high calcium levels in your blood.
Tell your doctor if you are breastfeeding, pregnant or plan to become pregnant.
Fact Box
Chemical Class
Parathyroid Hormone Analogs
Habit Forming
No
Therapeutic Class
HORMONES
Action Class
Parathyroid Hormone (PTH) Analogues
Interaction with drugs
Taking Osrise PTH with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Etidronate may reduce the efficacy of Teriparatide.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Pamidronate may reduce the efficacy of Teriparatide.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Risedronate may reduce the efficacy of Teriparatide.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Dear mam as your case is a chronic case it requires long case taking, examination and regular follow up, therefore, please visit a homeopath so that he can examine you and guide you accordingly.
Share x-rays and other investigation reportsTake Cap Uprise D3 60k once weekly and Cap Bio-D3-strong once daily for 3 monthsTake Cap Altraday once daily for pain relief
No, Osrise PTH Injection is not a steroid. However, this medicine may be used to treat osteoporosis caused by long-term use of steroids. Generally, this medicine is used to treat osteoporosis in women of postmenopausal age group and in men who have increased risk of fracture.
Can I take this medication in long term for osteoporosis?
Osrise PTH Injection should not be taken for longer than 2-year course. It is important to inform the doctor if you have taken this medication in the past, as you should not receive more than one treatment of 24 months course more than once in your lifetime.
How is Osrise PTH Injection stored at home?
Always keep this medicine stored in a refrigerator at a temperature of about 2°C to 8°C. Be cautious, the temperature should not decrease further as freezing may cause the medicine to get damaged and can lead to loss of activity. Therefore, avoid placing the Osrise PTH Injection pens close to the ice compartment of the refrigerator. If properly stored this medication can be used up to 28 days after the first injection. If the pen is not empty within 28 days please discard it safely.
Who should not use Osrise PTH Injection?
The doctor will decide whether the medicine is required for a patient or not. There are few conditions in which the use of Osrise PTH Injection should be avoided such as in patients with kidney impairment, Paget’s disease, any type of bone cancers or unexplained high levels of serum calcium. It should also be avoided by children, young adult or growing age, pregnant or lactating females. Hence, before starting the medication inform the doctor about any medical condition and the medication you are taking. This will help the doctor to design a proper therapy for you.
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References
Bikle DD. Agents That Affects Bone Mineral Homoestasis. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 766.
Friedman PA. Agents Affecting Mineral Ion Homeostasis and Bone Turnover. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1300