Osteo Plus 35 Tablet is used to treat or prevent weakening of the bones (osteoporosis) caused by menopause or use of steroids. Using this medicine can reduce your risk of breaking bones.
Osteo Plus 35 Tablet is best taken without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. Do not stop taking it until you have finished, even when you feel better. It may take several days to get the full benefit of this drug. Osteo Plus 35 Tablet is only part of a programme of treatment that may also include changes to your diet and taking calcium and vitamin supplements.
The most common side effects include headache, musculoskeletal (bone, muscle or joint) pain, indigestion, heartburn and diarrhea. These are usually mild and will disappear after a short time. If they do not go away, tell your doctor. Osteo Plus 35 Tablet can cause serious kidney problems, especially if you are dehydrated, if you take diuretic medicine (water pills), or if you already have kidney disease. It can also cause low levels of calcium in the blood and pain in the mouth or jaw. These are serious side effects and need urgent medical attention. Tell your doctor straight away.
You should not be given this medicine if you are breastfeeding. Before taking it, tell your doctor if you have kidney problems or low calcium levels. Also let your doctor know what other drugs you are taking. Some of them may affect, or be affected by, this injection, especially medicines used to treat severe infections and medicines used to treat cancer and osteoporosis. You may need frequent medical tests to check your kidney function and mineral levels. Avoid smoking or try to quit as smoking can reduce your bone mineral density, making fractures more likely. Drinking large amounts of alcohol can also cause bone loss and should be avoided.
Osteoporosis is a common condition that weakens bones, making them fragile and more likely to break. It often occurs in women after menopause or who are taking steroids. This condition can be treated with bone-strengthening medicines. Osteo Plus 35 Tablet slows down the rate at which bone is broken down in your body. This maintains bone density and reduces your risk of breaking a bone. You can also help improve the strength of your bones by doing regular exercise (especially weight-bearing exercise), eating healthy foods containing calcium and Vitamin D, and reducing your consumption of alcohol and tobacco. Supplements of calcium and Vitamin D3 are also effective.
Side effects of Osteo Plus Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Osteo Plus
Headache
Musculoskeletal (bone, muscle or joint) pain
Heartburn
Diarrhea
Indigestion
How to use Osteo Plus Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Osteo Plus 35 Tablet is to be taken empty stomach.
How Osteo Plus Tablet works
Osteo Plus 35 Tablet is a bisphosphonate. It acts by suppressing the activity of osteoclasts, cells that cause the destruction of bone, thereby strengthening the bones and minimizing the risk of fractures.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Osteo Plus 35 Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Osteo Plus 35 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Osteo Plus 35 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
SAFE
Osteo Plus 35 Tablet does not usually affect your ability to drive.
Kidney
CAUTION
Osteo Plus 35 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Osteo Plus 35 Tablet may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Osteo Plus 35 Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Osteo Plus 35 Tablet may not be needed in these patients. Please consult your doctor.
What if you forget to take Osteo Plus Tablet?
If you miss a dose of Osteo Plus 35 Tablet, skip it and continue with your normal schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Take it first thing in the morning on an empty stomach. Do not lie down after taking the medicine.
Wait at least 1 hour before taking any other medication or eating or drinking anything.
Take calcium and vitamin D to help build your bones when taking Osteo Plus 35 Tablet.
Do not take it during pregnancy or breastfeeding. Tell your doctor if you become pregnant while taking Osteo Plus 35 Tablet.
Inform your doctor if you experience pain in jaw. This problem may be seen after dental work.
Your doctor will monitor your response to Osteo Plus 35 Tablet by testing your bone mineral density (BMD). This is usually done every 1-3 years.
It is important to look after your mouth and teeth while you are taking this medicine. Have regular dental check-ups and inform your dentist about taking Osteo Plus 35 Tablet.
Fact Box
Chemical Class
Bisphosphonate Derivative
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
Bone resorption inhibitor -Bisphosphonates
Patient concerns
Calcium defiecincy osteoporosis Joint pain Should go for joint replacement? Please recommend medication for pain and muscular stiffness
Dr. Akshat Goel
Orthopaedics
Tab Brutaflam-MR4 twice daily and Cap Osteo-plus once daily
Please let me know if I need calcium or vitamin d3 supplements since I'm a smoker, have earlier problems of disc rupture. Also I played soccer earlier when this rupture happened and stopped for 2-3 years, now again i'm planning to play soccer. please advise.
Osteo Plus 35 Tablet should be taken in the morning after getting up on an empty stomach with a full glass of water. Do not lie down and stay fully upright for at least 30 minutes after swallowing the medicine. Avoid taking any food or medication just after taking Osteo Plus 35 Tablet, maintain a gap of at least 30 minutes. Take this medicine only after consulting the doctor and follow the instructions advised.
Q. Why can you not lie down after taking Osteo Plus 35 Tablet?
It is advised not to lie down after taking Osteo Plus 35 Tablet as there is a possibility that the medication might come back up into the esophagus (food pipe). As a result, the esophagus may get damaged. Staying upright will help the medicine to settle down quickly in your stomach and prevent side effects like heartburn and pain.
Q. Does Osteo Plus 35 Tablet cause hair loss?
Yes, Osteo Plus 35 Tablet can cause hair loss, but this is not a common side effect. If you experience hair loss while taking this medication immediately report to your doctor and follow the advice given.
Q. Can Osteo Plus 35 Tablet be used in pregnant women?
Osteo Plus 35 Tablet should be avoided during pregnancy. There is a lack of data regarding the use of Osteo Plus 35 Tablet in pregnant women. You should consult your doctor if you are pregnant or planning to get pregnant before taking this medication.
Q. What other lifestyle changes should I make?
To get maximum benefit from Osteo Plus 35 Tablet, there are certain lifestyle changes that you must adhere to. Include some calcium or Vitamin D rich foods for bone strength. Try to spend more time in sunlight to get natural vitamin D. Quit smoking and reduce alcohol consumption as they may harm your bones. You can take up an exercise regime such as walking and low-impact aerobics as they are good for your bones. Similarly, you can try strength-training exercises where you use your own body weight which in turn improve bone health.
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References
Bikle DD. Agents That Affects Bone Mineral Homoestasis. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 766.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1219-20.
Medscape. Risedronate. [Accessed 02 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
Risedronate sodium [EMC Label]. Camberley, UK: Sandoz Limited; 2020. [Accessed 28 Mar. 2023] (online) Available from:
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