Oxerif 450mg Tablet is used to treat and prevent epilepsy (seizures). However, it cannot cure epilepsy and will only work to prevent seizures for as long as you continue to take the medicine.

Oxerif 450mg Tablet may be used alone or in combination with other medicines. The dose and how often you need to take it will be decided by your doctor so that you get the right amount to control your symptoms. It may be increased gradually. You can take this medicine with or without food but take it at the same time each day to get the most benefit. It usually takes a couple of weeks to work. It is important to take this medicine regularly and for as long as you are advised, even if you feel well. Missing doses may trigger seizures and, if you stop, your condition may get worse. It should never be stopped suddenly.

The most common side effects of this medicine include nausea, vomiting, feeling dizzy, tired or drowsy, unsteadiness, and low sodium levels in blood. Most of these are not serious. Keep taking the medicine but talk to your doctor if these side effects bother you or do not go away. However, if you notice a skin rash or redness, tell your doctor straight away. It could develop into a life-threatening skin condition called Stevens-Johnson syndrome. Long-term treatment with this medicine can cause osteoporosis (reduced bone mass) and increase your risk of breaking a bone. Anticonvulsants like this medicine may cause suicidal thoughts and behaviors. If your mood becomes depressed, tell your doctor.

This medicine may not be suitable for everybody. Before using it, tell your doctor if you have ever had heart problems, kidney or liver disease, difficulty urinating, depression, or suicidal thoughts. Many other medicines can interfere with it and some should not be taken together so tell your doctor all the medicines you are taking to make sure it is safe. If you are pregnant, do not start or stop taking this medicine without asking your doctor. Drinking alcohol should be avoided as it can increase some of the side effects and can also increase your risk of seizures. You may need frequent blood tests to help your doctor make sure you are taking the right dose both before you start and while you are using it.

Uses of Oxerif Tablet

Benefits of Oxerif Tablet

In Epilepsy/Seizures

Oxerif 450mg Tablet is an anticonvulsant (or anti-epileptic) medicine that works by decreasing the nerve impulses which cause the seizures. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. It helps reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety.
This medicine is not associated with any physical or psychological dependence (addiction) but it should not be stopped suddenly. It must be taken regularly as prescribed to be effective. Missing doses may trigger a seizure.

Side effects of Oxerif Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Oxerif

Headache
Nausea
Vomiting
Fatigue
Dizziness
Nystagmus (involuntary eye movement)
Tremors
Vertigo
Drowsiness
Abnormality of voluntary movements
Abnormal gait
Visual disturbance
Increased sodium level in blood

How to use Oxerif Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Oxerif 450mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Oxerif Tablet works

Oxerif 450mg Tablet is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

Safety advice

Alcohol

UNSAFE

Oxerif 450mg Tablet may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Oxerif 450mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Oxerif 450mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Baby should be monitored for excessive sleepiness and weight gain.

Driving

UNSAFE

Oxerif 450mg Tablet may cause side effects which could affect your ability to drive.
Oxerif 450mg Tablet may make you feel sleepy or dizzy, or may cause blurred vision, lack of muscle coordination, especially when starting treatment or increasing the dose. This may affect your driving ability.

Kidney

CAUTION

Oxerif 450mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Oxerif 450mg Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Oxerif 450mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Oxerif 450mg Tablet may be needed. Please consult your doctor.
Dose adjustment is not recommended in patients with mild to moderate liver disease.

What if you forget to take Oxerif Tablet?

If you miss a dose of Oxerif 450mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Oxerif 450mg Tablet

₹18.8/Tablet

Oxetol 450 Tablet

Sun Pharmaceutical Industries Ltd

₹23.5/tablet

25% costlier

Zenoxa 450 Tablet

Intas Pharmaceuticals Ltd

₹24.6/tablet

31% costlier

Oxcarb 450 Tablet

Cipla Ltd

₹20.28/tablet

8% costlier

Oxmazetol 450 Tablet

Abbott

₹22.99/tablet

22% costlier

Vinlep 450 Tablet

Sanofi India Ltd

₹31.88/tablet

70% costlier

View all substitutes

Quick tips

Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
Some healthy tips to prevent seizures:
- Practice yoga every day.
- Get enough sleep at nighttime.
- Limit the use of screen time such as mobile/laptop.
- Take your medication on time.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
It may increase the risk of low sodium levels in the blood. Inform your doctor if you develop difficulty concentrating, memory problems, confusion, weakness, and unsteadiness.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
Oxerif 450mg Tablet helps in the treatment and prevention of seizures.
Take it at the same time every day to maintain consistent levels in your body.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking Oxerif 450mg Tablet, as it may cause excessive sleepiness or drowsiness.
Monitor your weight during treatment with this medicine as it can cause weight gain.
Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
Do not take Oxerif 450mg Tablet if you are pregnant or planning to conceive or breastfeeding.
Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
Some healthy tips to prevent seizures:
- Practice yoga every day.
- Get enough sleep at nighttime.
- Limit the use of screen time such as mobile/laptop.
- Take your medication on time.
It may increase the risk of low sodium levels in the blood. Inform your doctor if you develop difficulty concentrating, memory problems, confusion, weakness, and unsteadiness.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.

Fact Box

Chemical Class

Iminostilbene Derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Sodium Channel Modulators- Antiepileptic drugs (AEDs)

Interaction with drugs

Taking Oxerif with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Sofosbuvir (Oral Route) Severe

Oxcarbazepine may reduce blood levels and efficacy of Sofosbuvir. Do not consume Sofosbuvir with Oxcarbazepine.

Tenofovir Alafenamide (Oral Route) Severe

Oxcarbazepine may reduce blood levels of Tenofovir Alafenamide. Do not use Tenofovir Alafenamide with Oxcarbazepine. If concurrent use is essential, talk to your doctor.

Clozapine (Oral Route) Severe

Oxcarbazepine may reduce the efficacy of Clozapine. Your doctor may monitor your blood cell count and adjust the doses as per the observations.

Ulipristal acetate (Oral Route) Severe

Oxcarbazepine may reduce the efficacy of Ulipristal acetate. Do not consume Ulipristal acetate with Oxcarbazepine. If Ulipristal acetate is essential, ensure a gap of At least 4 w... More

Pazopanib (Oral Route) Severe

Oxcarbazepine may reduce blood levels of Pazopanib. Do not consume Pazopanib with Oxcarbazepine.

View all drug interactions

Patient concerns

She has problem of epilepsy from last two years

Dr. Rahul Yadav

Paediatrics

Hello, epilepsy and seizures cannot be treated online without physically examining the child and detailed history.

Left side headache while laughing or coughing for 20 seconds only Pls suggest

Dr. Pushkar Mani

Physician

could be trigeminal neuralgia/ TM joint stifness or migrainerefer to ENT doctor and Neurophysician

I m taking 1.5gm sodium valporate,1.5 levectram, 1gm clobezam then also seizure r their at period of weekly is there alternate treatment in Ayurveda as every time at multiplying the doses at every visit As MRI eeg every tests r normal

Dr. M. K. Ansari

Neurology

not aware of any ayurvedic medications for epilepsy is not my specialization. However you seems to have difficult to control (intractable) seizures plz follow doctors advice deligently for ur own welfare

?? ???? ?????? ?? ?????? ?? ?? ??? encorate Charon 200 500 tablet use krta hu kya iska koi solution h Jisse main completely thk ho jau

Dr. Jyoti Kapoor Madan

Psychiatry

Epilepsy requires regular treatment with anticonvulsants like encorate chrono for at least 3 years of seizure free period after which medicines may be tapered off unless seizures reappear. At present, there are no other effective treatment options.

FAQs

Does the use of Oxerif 450mg Tablet affect weight?

Yes, Oxerif 450mg Tablet affects weight and may cause weight gain. However, in some cases, weight loss has also been reported. Consult a dietician and follow a diet plan to maintain your weight.

What are the advantages of Oxerif 450mg Tablet over carbamazepine?

Oxerif 450mg Tablet has fewer side effects as compared to carbamazepine. Moreover, Oxerif 450mg Tablet can be started with a clinically effective dose as against carbamazepine which may require frequent visits to the doctor before an effective dose can be decided based on the patient’s response to the treatment.

How can I watch for early symptoms of suicidal thoughts and actions?

You should pay attention to any changes, especially sudden changes in mood, behaviour, thoughts or feelings. Be aware of common warning signs that might be a signal for risk of suicide. Some of these include talking or thinking about hurting yourself or ending your life, withdrawing from friends and family, becoming depressed or worsening your depression. Keep your appointment with your doctor on schedule, do not miss. Stay connected with the doctor even between visits.

When and how should I take Oxerif 450mg Tablet?

Take Oxerif 450mg Tablet exactly as directed by your doctor. It is recommended that you take it twice every day, unless your doctor tells you otherwise. Oxerif 450mg Tablet can be taken with or without food. Take your medicine at the same time each day to gain maximum benefit. It will also help you remember when to take it.

For how long do I need to take Oxerif 450mg Tablet. Can I stop taking it on my own?

You should take your medicine for the time and duration prescribed by your doctor. Oxerif 450mg Tablet helps to control your epilepsy but does not cure it. You must take this medicine every day, even if you feel well. Do not stop taking Oxerif 450mg Tablet or lower the dose yourself. Stopping your medicine suddenly or lowering the dose may cause seizures. Consult your doctor who may reduce the dose gradually before stopping it completely.

Will the use of Oxerif 450mg Tablet affect my fertility?

Oxerif 450mg Tablet is not know to affect fertility in males or females. However, talk to your doctor if you are facing fertility issues while taking this medicine.

Does Oxerif 450mg Tablet cause hair loss?

Yes, Oxerif 450mg Tablet causes hair loss as a common side effect. However, it does not affect everyone. If there is substantial hair loss, consult your doctor.

Who should not take Oxerif 450mg Tablet?

You should not take Oxerif 450mg Tablet if you are allergic to Oxerif 450mg Tablet, eslicarbazepine or to any of their components. Also, pregnant women and women who take birth control pills should avoid Oxerif 450mg Tablet. Along with that, people having severe liver or kidney disease and people with a psychiatric disorder should avoid taking Oxerif 450mg Tablet.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Stahl SM, editor. Oxcarbazepine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 497-501.
Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 406-407.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1037-38.
Oxcarbazepine. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2000 [16 Nov. 2018]. [Accessed 22 Jan. 2019] (online) Available from:
Oxcarbazepine. Dublin 13, Ireland: Gerard Laboratories; 2018. [Accessed 17 Jun. 2019] (online) Available from:
Oxcarbazine. Mumbai, India: Sun Pharmaceutical Industries Ltd.; 2007. [Accessed 25 Mar 2019] (online) Available from:
Oxcarbazepine. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2000 [revised Jan. 2019]. [Accessed 17 Jun. 2019] (online) Available from:
Oxcarbazepine. Macquarie Park, New South Wales: Novartis Pharmaceuticals Australia Pty Limited; 2017. [Accessed 17 Jun. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Oxcarbazepine. [Updated 2020 Jan 20]. [Accessed 20 Feb. 2020] (online) Available from:
Drugs.com. Oxcarbazepine. [Accessed 25 Mar 2019] (online) Available from:
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Marketer details

Name: Gryff Pharmaceuticals Private Limited

Address: 178 Rajendra Nagar, Sohan Lal School, Lucknow UP 226004 IN

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.