Pefran 400mg Tablet
Prescription Required
Product introduction
Pefran 400mg Tablet is an antibiotic, used in the treatment of bacterial infections. It is also used in treating infections of the urinary tract, nose, throat, skin and soft tissues, and lungs (pneumonia). It cures the infection by stopping the further growth of the causative microorganisms.
Pefran 400mg Tablet should be used in the dose and duration as advised by your doctor. It should be taken with food, preferably at a fixed time. Avoid skipping any doses and finish the full course of treatment even if you feel better. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned.
You may experience nausea, headache, and dizziness as side effects of this medicine. These are usually temporary and resolve on their own. Consult your doctor if they bother you or persist for a longer duration. Diarrhea may also occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.
You should not take this medicine if you are allergic to any of its ingredients. Rarely, some people may have a severe allergic reaction that needs urgent medical attention. Signs of this include rash, swelling of the lips, tongue or face, shortness of breath, or breathing problems. Special care should be taken in people with kidney problems while taking this medicine.
Pefran 400mg Tablet should be used in the dose and duration as advised by your doctor. It should be taken with food, preferably at a fixed time. Avoid skipping any doses and finish the full course of treatment even if you feel better. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned.
You may experience nausea, headache, and dizziness as side effects of this medicine. These are usually temporary and resolve on their own. Consult your doctor if they bother you or persist for a longer duration. Diarrhea may also occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.
You should not take this medicine if you are allergic to any of its ingredients. Rarely, some people may have a severe allergic reaction that needs urgent medical attention. Signs of this include rash, swelling of the lips, tongue or face, shortness of breath, or breathing problems. Special care should be taken in people with kidney problems while taking this medicine.
Uses of Pefran Tablet
Benefits of Pefran Tablet
In Treatment of Bacterial infections
Pefran 400mg Tablet is an antibiotic medicine which can be used to treat many different infections caused by bacteria. These include infections of the ear, nose, throat, lungs, urinary tract, skin, and soft tissues in adults and children. It works by killing and stopping the growth of the bacteria causing the infection.
This medicine usually makes you feel better quite quickly. However, you should continue taking it as long as it is prescribed even when you feel better, to make sure that all bacteria are killed and do not become resistant.
This medicine usually makes you feel better quite quickly. However, you should continue taking it as long as it is prescribed even when you feel better, to make sure that all bacteria are killed and do not become resistant.
Side effects of Pefran Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pefran
- Nausea
- Diarrhea
- Headache
- Dizziness
How to use Pefran Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pefran 400mg Tablet is to be taken with food.
How Pefran Tablet works
Pefran 400mg Tablet is an antibiotic. It works by stopping the action of a bacterial enzyme called DNA-gyrase. This prevents the bacterial cells from dividing and repairing, thereby killing them.
Safety advice
Alcohol
SAFE
Consuming alcohol with Pefran 400mg Tablet does not cause any harmful side effects.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Pefran 400mg Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Pefran 400mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Pefran 400mg Tablet may cause side effects which could affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Pefran 400mg Tablet in patients with kidney disease. Please consult your doctor.
Liver
CAUTION
Pefran 400mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Pefran 400mg Tablet may be needed. Please consult your doctor.
What if you forget to take Pefran Tablet?
If you miss a dose of Pefran 400mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Pefran 400mg Tablet
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Quick tips
- Your doctor has prescribed Pefran 400mg Tablet to cure your infection and improve symptoms.
- Do not skip any doses and finish the full course of treatment even if you feel better.
- Discontinue Pefran 400mg Tablet and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
- Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
- Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Fact Box
Chemical Class
Fluoroquinolone
Habit Forming
No
Therapeutic Class
OPHTHAL OTOLOGICALS
Action Class
Quinolones/ Fluroquinolones
Interaction with drugs
Taking Pefran with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Pefloxacin may reduce the efficacy of Cholera Vaccine (Inactivated).
Do not consume Cholera Vaccine (Inactivated) two weeks before and at least 10 days after consuming Pefloxacin.
Pefloxacin may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine.
Do not consume Purified Vi Polysaccharide Typhoid Vaccine with Pefloxacin. If Purified Vi Polysac
Pefloxacin may reduce blood levels of Mycophenolate mofetil.
Your doctor may monitor the effects of Mycophenolate mofetil along with your overall treatment and adjust the doses as
Pefloxacin may raise blood levels of Zolmitriptan.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Concurrent use may increase the risk of bleeding.
Your doctor may frequently monitor your blood clotting time and adjust the dose of Acenocoumarol accordingly.
Patient concerns
FAQs
Can the use of Pefran 400mg Tablet cause diarrhea?
Yes, the use of Pefran 400mg Tablet can cause diarrhea. It is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If you are experiencing severe diarrhea, talk to your doctor about it.
Can the use of Pefran 400mg Tablet increase the risk of muscle damage?
Yes, use of Pefran 400mg Tablet is known to increase the risk of muscle damage, commonly in the ankle (achilies tendon). Muscle damage can happen in people of all ages who take Pefran 400mg Tablet. Inform your doctor if you feel any kind of muscle pain while using this medicine.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- PubChem. Pefloxacin. [Accessed 01 Apr. 2019] (online) Available from:
- ScienceDirect. Pefloxacin. [Accessed 01 Apr. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 01 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:
Marketer details
Name: Biochem Pharmaceutical Industries
Address: BIOCHEM PHARMA, LG 113 / A, Xth Central Mall, Mahavir Nagar, 90ft Road, Next to D Mart, Kandivali - West, Mumbai - 400067.
Country of origin: India
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
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