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MBA, MD Pharmacology
Last updated
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Pemmet 500 Injection

Prescription Required
SALT COMPOSITION
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.

Product introduction

Pemmet 500 Injection is used in the treatment of non-small cell lung cancer and malignant pleural mesothelioma.

Pemmet 500 Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, loss of appetite, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver and blood uric acid levels.

Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using.This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Pemmet Injection

Benefits of Pemmet Injection

In Non-small cell lung cancer

Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Pemmet 500 Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

In Malignant pleural mesothelioma

Malignant pleural mesothelioma is a form of cancer that develops in the lungs and the inner side of the ribs. It is a very aggressive form of lung cancer. Pemmet 500 Injection is used along with some other medicines to treat this cancer. It kills the cancer cells, and prevents the further multiplication of cancer cells. This restricts the spread of cancer to other unaffected areas. Follow your doctor’s instructions carefully and consult your doctor if you have any doubts.

Side effects of Pemmet Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pemmet

  • Nausea
  • Vomiting
  • Sore throat
  • Loss of appetite
  • Stomatitis (Inflammation of the mouth)
  • Hair loss
  • Low blood platelets
  • Rash
  • Fatigue
  • Anemia (low number of red blood cells)
  • Diarrhea
  • Decreased white blood cell count (neutrophils)
  • Neuropathy

How to use Pemmet Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Pemmet Injection works

Pemmet 500 Injection interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.

Safety advice

Alcohol
SAFE
Consuming alcohol with Pemmet 500 Injection does not cause any harmful side effects.
Pregnancy
CONSULT YOUR DOCTOR
Pemmet 500 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CAUTION
Pemmet 500 Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Driving
UNSAFE
Pemmet 500 Injection may cause side effects which could affect your ability to drive.
Pemmet 500 Injection may make you feel tired and this may affect your ability to drive.
Kidney
CAUTION
Pemmet 500 Injection should be used with caution in patients with kidney disease. Dose adjustment of Pemmet 500 Injection may be needed. Please consult your doctor.
Use of Pemmet 500 Injection is not recommended in patients with moderate to severe kidney disease.
Liver
SAFE IF PRESCRIBED
Pemmet 500 Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pemmet 500 Injection may not be needed in these patients. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Pemmet 500 Injection
₹5405/Injection
Alimta 500mg Injection
Eli Lilly and Company India Pvt Ltd
₹30000/injection
449% costlier
Pemnat 500mg Injection
Natco Pharma Ltd
₹2442.46/injection
55% cheaper
Pemetero 500 Injection
Hetero Drugs Ltd
₹2673/injection
51% cheaper
₹21374/injection
291% costlier
Medipem 500 Injection
Medion Biotech Pvt Ltd
₹5214/injection
5% cheaper

Quick tips

  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

Fact Box

Chemical Class
Glutamic Aacid Derivatives
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Antimetabolites

Patient concerns

arrow
What is the purpose of Chemotherepy given at the time of radiotherapy in ca lung small cell carcinoma
Dr. Vijay Sharnangat
Medical Oncology and Hematology
This is given to enhance the therapeutic effect of radiation therapy which is curative for small cell lung cancer.
Good evening, my father is suffering from lung cancer naming malignant mesothelioma. The same type of cancer my grandmother have. They both died due to this cancer disease. I want to know that is this a heridatory type of cancer? Is there is any probability in future that I will suffer from this type of cancer. Actually is their any preventive type of measures that I can follow that will help me prevent in future from suffering from cancer. Is their any tests available to keep regular updates about the trace of the cancer,
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Restrain from any addiction, have regular exercise, eat healthy food.It's not hereditary, please don't get afraid.
arrow

FAQs

Is Pemmet 500 Injection a vesicant?

No. Pemmet 500 Injection is not a vesicant.

Is Pemmet 500 Injection safe?

Pemmet 500 Injection is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

Does Pemmet 500 Injection cause hair loss?

Yes. Pemmet 500 Injection is a prescription chemotherapy medication and hair loss is one of the possible side effects.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 946.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1077.
  3. Pemetrexed disodium. Basingstoke, Hampshire: Eli Lilly and Company Limited; 2004 [revised 10 Jan. 2019]. [Accessed 28 Jan. 2019] (online) Available from:External Link
  4. Pemetrexed. Indianapolis, Indiana: Lilly USA; 2004 [revised Sep. 2013]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Country of origin: India

NOT FOR SALE
We do not facilitate sale of this product at present

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