Penosyl 8mg Tablet belongs to a group of medicines known as angiotensin-converting enzyme (ACE) inhibitors. It is widely used to treat high blood pressure and heart failure and may be prescribed after a heart attack. It also lowers the chances of having a heart attack or stroke.

Penosyl 8mg Tablet can be prescribed either alone or in combination with other medicines. It should be taken on an empty stomach. This medicine should be taken at the same time each day to get the most benefit. It is important to continue taking it regularly even if you feel well or even if your blood pressure is controlled. Most people with high blood pressure do not feel ill, but if you stop taking this medicine, your condition could get worse. This medicine is considered safe for long-term use.

Making some changes in your lifestyle will also help lower your blood pressure. These may include regular exercise, losing weight, smoking cessation, reducing alcohol intake, and reducing the amount of salt in your diet as advised by your doctor. The most common side effects of this medicine include decreased blood pressure, cough, the increased potassium level in blood, fatigue, weakness, and dizziness. Most of these are temporary and resolve with time. Talk to your doctor if any of the side effects bother you or do not go away.

Before taking this medicine, let your doctor know if you have any kidney or liver problems. Pregnant or breastfeeding mothers should also consult their doctor before taking it. Your doctor may check your kidney function, blood pressure, and potassium levels in your blood at regular intervals while you are taking this medicine.

Uses of Penosyl Tablet

Hypertension (high blood pressure)
Prevention of heart attack and stroke
Heart failure

Side effects of Penosyl Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Penosyl

Cough
Dizziness
Hypotension (low blood pressure)
Headache
Back pain

How to use Penosyl Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Penosyl 8mg Tablet is to be taken empty stomach.

How Penosyl Tablet works

Penosyl 8mg Tablet is an angiotensin converting enzyme (ACE) inhibitor. It works by reducing stress on the heart and relaxing blood vessel so that blood flows more smoothly and the heart can pump blood more efficiently.

Safety advice

Alcohol

UNSAFE

Penosyl 8mg Tablet may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Penosyl 8mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Penosyl 8mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Penosyl 8mg Tablet may cause side effects which could affect your ability to drive.
Penosyl 8mg Tablet usually does not affect alertness but dizziness or weakness due to low blood pressure may occur in some patients. This may affect your driving ability.

Kidney

CAUTION

Penosyl 8mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Penosyl 8mg Tablet may be needed. Please consult your doctor.
Caution should be advised in patients with renal impairment.

Liver

CAUTION

Penosyl 8mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Penosyl 8mg Tablet may be needed. Please consult your doctor.
Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine.

What if you forget to take Penosyl Tablet?

If you miss a dose of Penosyl 8mg Tablet, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Penosyl 8mg Tablet

₹11.7/Tablet

Coversyl 8mg Tablet

Servier India Private Limited

₹24.6/tablet

110% costlier

Zimpril 8mg Tablet

Zim Laboratories Limited

₹13.6/tablet

16% costlier

Coveril 8 Tablet

Johnlee Pharmaceuticals Pvt Ltd

₹18.8/tablet

61% costlier

Perincov 8mg Tablet

Kasdap Healthcare Pvt Ltd

₹14.2/tablet

21% costlier

Perindosyl 8mg Tablet

Elder Pharmaceuticals Ltd

₹14.4/tablet

23% costlier

Quick tips

Penosyl 8mg Tablet can make you feel dizzy for the first few days, so rise slowly if you have been sitting or lying down. You can also prefer taking it at bedtime to avoid dizziness throughout the day.
Let your doctor know about any cough, or throat irritation that does not go away.
It may increase the level of potassium in blood. Avoid taking potassium supplements and potassium-rich foods such as banana and broccoli.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
You have been prescribed Penosyl 8mg Tablet to improve blood pressure.
Lowering blood pressure reduces the chance of future heart attack & strokes.
It may also be used to treat chronic (long-standing) heart failure.
It protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney diseases.
Penosyl 8mg Tablet can make you feel dizzy for the first few days, so rise slowly if you have been sitting or lying down. You can also prefer taking it at bedtime to avoid dizziness throughout the day.
Let your doctor know about any cough, or throat irritation that does not go away.
It may increase the level of potassium in blood. Avoid taking potassium supplements and potassium-rich foods such as banana and broccoli.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Fact Box

Chemical Class

Dipeptides

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Angiotensin-Converting Enzyme (ACE) Inhibitors

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FAQs

What is Penosyl 8mg Tablet? What is it used for?

Penosyl 8mg Tablet belongs to a group of medicines known as angiotensin-converting enzyme (ACE) inhibitors. It relaxes and widens the blood vessels, making it easier for the blood to pass through the vessels. As a result of this, the heart does not have to work more to push the blood. Since the workload on the heart is reduced, it helps to lower the blood pressure and thus reduces the risk of heart attack and stroke. It is also used for the treatment and prevention of congestive heart failure.

What other lifestyle changes should I make while taking Penosyl 8mg Tablet?

Lifestyle changes play a major role in keeping you healthy if you are taking Penosyl 8mg Tablet. Avoid taking excess salt in your diet and find ways to reduce or manage stress in your life. Practise yoga or meditation or take up a hobby. Ensure that you have a sound sleep every night as this also reduces your stress and hence helps in keeping your blood pressure normal. Stop smoking and taking alcohol as this helps in lowering your blood pressure and helps to prevent heart problems. Exercise regularly and take a balanced diet that includes whole grains, fresh fruits, vegetables and fat-free products. You should consult your doctor if you need any further help to get maximum benefit of Penosyl 8mg Tablet and to keep healthy.

I feel better after taking Penosyl 8mg Tablet, can I stop taking it?

No, continue taking Penosyl 8mg Tablet even if you feel better and your blood pressure is under control. Stopping Penosyl 8mg Tablet suddenly may cause your blood pressure to increase and your chances of stroke or heart attack may rise. Usually once you start taking any medicine for controlling blood pressure, you have to continue taking it life long unless you cannot tolerate it.

Will Penosyl 8mg Tablet make me feel dizzy? What should I do about it?

Yes, Penosyl 8mg Tablet may make you feel dizzy or lightheaded. If Penosyl 8mg Tablet makes you feel dizzy when you stand up, try getting up very slowly or stay seated until you feel better. If you begin to feel dizzy, lie down so that you don't faint, then sit until you feel better. Don’t drive, do not use tools or machines and avoid anything requiring concentration while you're feeling dizzy or shaky.

What time of the day should I take Penosyl 8mg Tablet?

Penosyl 8mg Tablet should be taken at the same time each day to reduce the chances of a missed dose. Take it in the dose and duration prescribed by the doctor. Your doctor may advise you to take your first dose before bedtime, because it can make you dizzy. After the first dose, if you do not feel dizzy, you may take Penosyl 8mg Tablet at any time of the day. Your dose will depend on the condition you are being treated for and therefore, it will vary from person to person. If you experience any side effects while taking Penosyl 8mg Tablet, please consult your doctor.

Can Penosyl 8mg Tablet increase potassium levels? If so, what should be done?

Penosyl 8mg Tablet may increase potassium levels in the blood, especially if you have uncontrolled diabetes mellitus, kidney problems and dehydration. Potassium levels may also increase in patients using potassium salts or medicines which increase potassium levels or are aged more than 70 years of age. If you have any of these conditions and are using Penosyl 8mg Tablet, you need to be careful and get regular blood tests done to monitor potassium levels.

After starting Penosyl 8mg Tablet, I have developed dry cough which is very irritating and is not getting better with any medicine. What should I do now?

Penosyl 8mg Tablet may cause dry cough, as a side effect in some people. This can be persistent and may not be relieved by any medicine. Talk to your doctor if it bothers you or if you have trouble sleeping. Your doctor may suggest ways of managing the cough or may prescribe another medicine. Remember, do not stop taking Penosyl 8mg Tablet without consulting your doctor as it may increase your blood pressure and put you at a risk of developing a heart attack or stroke. Even if you stop taking Penosyl 8mg Tablet, the cough may take a few days to a month to resolve completely.

Can Penosyl 8mg Tablet affect my fertility?

There is no evidence that Penosyl 8mg Tablet has any effect on fertility in both men and women. However, if you are planning to get pregnant, talk to your doctor first because Penosyl 8mg Tablet is not recommended in pregnancy.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Pfeffer MA, Opie LH. Inhibitors of the Renin-Angiotensin-Aldosterone System. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 143.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1091-92.
Perindopril erbumin. Cincinnati, Ohio: Patheon Pharmaceuticals, Inc.; 2005. [Accessed 20 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Perindopril. [Updated 2019 Feb 28]. [Accessed 19 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation. Perindopril erbumine. [Accessed 05 Aug. 2023] (online) Available from:
Simpson D, Noble S, Goa KL. Perindopril: in congestive heart failure. Drugs. 2002;62(9):1367-77; discussion 1378-9. [Accessed 05 Aug. 2023] (online) Available from:
Perindopril erbumine [Prescribing Information]. Hyderabad, India: Aurobindo Pharma Limited; 2023. [Accessed 25 Jul. 2023] (online) Available from:

Marketer details

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Address: A,B,C-111, SAKAR COMPLEX, SANSTHA VASAHAT, RAOPURA, Vadodara-390001, Gujarat, India

Country of origin: India

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