Pentoblad 100 Capsule

Written By Dr. Lipika Khurana, PGDHHM, BDS

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 07 Dec 2025 | 01:00 AM (IST)

Pentoblad 100 Capsule is used to treat bladder pain or discomfort associated with interstitial cystitis (painful bladder syndrome). It works by forming a protective layer on the bladder wall, preventing irritating substances in urine from causing further irritation and damage.

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₹5253 MRP ₹6093.7514% off

Pentoblad 100 Capsule is currently sold out

Same composition alternative:

For-IC Capsule

₹849~~₹921~~

Available alternative from Cipla

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Pentoblad 100 Capsule

bottle of 90 capsules

₹5253

~~₹6093.75~~

Same composition

For-IC Capsule

strip of 10 capsules

Pentosan polysulfate sodium (100mg)

by Cipla Ltd

₹849

₹72.2 per capsule

₹722

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General Information

Contains

Pentosan polysulfate sodium (100mg)

Marketer

AMPS Biotech Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Pentoblad 100 Capsule is advised to take it in a dose and duration as per prescription. It should be taken on an empty stomach at least an hour before having a meal. Swallow the medicine as a whole without crushing or chewing it. You should not stop taking the medicine without consulting the doctor, as it may lead to the worsening of your symptoms.

Some of the common side effects of this medicine include hair loss, diarrhea, nausea, rash, and headache. In rare cases, blurred vision or difficulty adjusting to low light may occur with long-term use. If any side effects become bothersome or do not go away, inform your doctor. Seek medical attention if you experience unusual bleeding, severe stomach pain, or significant vision changes.

Do not take Pentoblad 100 Capsule if you are allergic to it. Inform your doctor if you have bleeding disorders, liver disease, or eye problems. This medicine may increase bleeding risk and affect vision with long-term use, so regular check-ups are advised. If you are pregnant, breastfeeding, or planning surgery, consult your doctor before use.

Uses of Pentoblad Capsule

Interstitial cystitis

Benefits of Pentoblad Capsule

Interstitial cystitis
Interstitial cystitis (IC), also known as painful bladder syndrome, is a chronic condition that causes bladder pressure, bladder pain, and sometimes pelvic pain. It occurs when the protective lining of the bladder is damaged, leading to irritation and inflammation. Pentoblad 100 Capsule helps by forming a protective layer on the bladder wall, reducing irritation and inflammation. This relieves pain, improves bladder function, and reduces the urgency and frequency of urination, helping patients manage daily life more comfortably.

Side effects of Pentoblad Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pentoblad

Hair loss
Abdominal pain
Abnormal liver function
Rash
Diarrhea
Nausea
Liver dysfunction
Dizziness
Headache

How to use Pentoblad Capsule

Take this medicine in the dose and duration as advised by your doctor. Pentoblad 100 Capsule is to be taken on an empty stomach.

How Pentoblad Capsule works

Pentoblad 100 Capsule works by attaching to the bladder wall and forming a protective barrier. This helps prevent harmful substances in urine from irritating the bladder lining. Additionally, it has mild blood-thinning properties and may improve blood flow to the bladder, supporting healing and reducing inflammation.

All substitutes for Pentoblad 100 Capsule

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Take it at least 1 hour before meals or 2 hours after meals.
Inform your doctor if you will be undergoing any surgery or are taking anticoagulants such as warfarin sodium, heparin, or high doses of aspirin, as Pentoblad 100 Capsule may increase the risk of bleeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Pentoblad 100 Capsule. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Pentoblad 100 Capsule during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CAUTION

Pentoblad 100 Capsule should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

CONSULT YOUR DOCTOR

It is not known whether Pentoblad 100 Capsule alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Pentoblad 100 Capsule in patients with kidney disease. Please consult your doctor.

Liver

CAUTION

Pentoblad 100 Capsule should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Pentoblad with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Apixaban (Oral Route)

Do not consume Apixaban with Pentosan polysulfate sodium. If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Pentosan polysulfate sodium may increase the effect of Apixaban.

Moderate

Rivaroxaban (Oral Route)

Do not consume Rivaroxaban with Pentosan polysulfate sodium. If concurrent use is essential, watch out for bleeding and consult your doctor immediately. They may adjust the dose of Pentosan polysulfate sodium accordingly.

Moderate

Dabigatran Etexilate (Oral Route)

Do not consume Dabigatran Etexilate with Pentosan polysulfate sodium. If concurrent use is essential, please consult your doctor.

Moderate

Dasatinib (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Your doctor may change the treatment accordingly.

Moderate

Bevacizumab (Injection Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately.

Frequently asked questions

Is Pentoblad 100 Capsule a steroid?

No, Pentoblad 100 Capsule is not a steroid. It is used in the treatment of interstitial cystitis, which is also known as bladder pain syndrome. This condition can cause sores and small areas of bleeding on the inside of the bladder, leading to pain and a frequent urge to urinate.

Can the use of Pentoblad 100 Capsule increase the risk of bleeding?

Yes, Pentoblad 100 Capsule is a weak anticoagulant, and it may increase your risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding, or if you notice blood in your stool.

Who should be cautious while starting Pentoblad 100 Capsule?

Do not take this medication without consulting your doctor. Inform the doctor if you have any disease for which you are taking blood-thinning medications like warfarin, heparin, aspirin, etc. This is done because the use of Pentoblad 100 Capsule can increase the risk of bleeding. Also, pregnant women and patients with liver problems should remain cautious while using this medicine.

How should I take Pentoblad 100 Capsule?

Pentoblad 100 Capsule should be taken in the dose as advised by the doctor. Take the medicine whole at least 1 hour before meals or 2 hours after meals, with one glass of water.

Fact Box

Chemical Class

O- glycosyl compounds

Habit Forming

Therapeutic Class

UROLOGY

Action Class

Semi-synthetic glycosaminoglycan

Related lab tests

Urine Routine & Microscopy

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1087-88.
Pentosan polysulfate sodium. Raritan, New Jersey: Ortho Women’s Health & Urology; 1998. [Accessed 04 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:
Pentosan polysulfate sodium [Prescribing Information]. Titusville, New Jersey: Janssen Pharmaceuticals, Inc.; 2024. [Accessed 11 Mar. 2025] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: AMPS Biotech Pvt Ltd
Address: 36/22, Near Annapurna Building, J B Nagar, Andheri East, Mumbai City, Maharashtra, 400069

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Pentoblad 100 Capsule

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Pentoblad Capsule

Benefits of Pentoblad Capsule

Side effects of Pentoblad Capsule

How to use Pentoblad Capsule

How Pentoblad Capsule works

All substitutes for Pentoblad 100 Capsule

Cystopen Capsule

For-IC Capsule

comforA Capsule

comforA Capsule

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Apixaban (Oral Route)

Rivaroxaban (Oral Route)

Dabigatran Etexilate (Oral Route)

Dasatinib (Oral Route)

Bevacizumab (Injection Route)

Frequently asked questions

Is Pentoblad 100 Capsule a steroid?

Can the use of Pentoblad 100 Capsule increase the risk of bleeding?

Who should be cautious while starting Pentoblad 100 Capsule?

How should I take Pentoblad 100 Capsule?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Urine Routine & Microscopy

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests