Peramnel 4 Tablet
Prescription Required
Product introduction
Peramnel 4 Tablet belongs to a class of medicines known as antiepileptics. It is used to treat epilepsy (seizures) in people who have repeated seizures (fits). It helps reduce the frequency of seizures that affect a part or whole of the brain.
Peramnel 4 Tablet is taken by mouth with or without food. However, it is advised to take it at the same time each day, preferably before going to bed. Take this medicine in the dose and duration as advised by your doctor as it has a high potential of habit-forming. If you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. Do not stop taking it suddenly without talking to your doctor as it may increase seizure frequency.
Some common side effects of this medicine include fatigue, anger, nausea, and balance disorder (loss of balance). It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain and to control it, you should have a balanced diet and exercise regularly. It is important to inform your doctor if you develop any unusual changes in mood or depression as it may lead to suicidal thoughts.
Before taking it, you should tell your doctor if you have kidney problems, depression, or suicidal thoughts and if you are pregnant or planning to become pregnant. You should not breastfeed while taking this medicine. Alcohol may increase the risk of seizures and worsen the side effects such as drowsiness and dizziness. Avoid alcohol while taking this medicine. Your kidney function may need to be tested often while taking this medicine.
Peramnel 4 Tablet is taken by mouth with or without food. However, it is advised to take it at the same time each day, preferably before going to bed. Take this medicine in the dose and duration as advised by your doctor as it has a high potential of habit-forming. If you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. Do not stop taking it suddenly without talking to your doctor as it may increase seizure frequency.
Some common side effects of this medicine include fatigue, anger, nausea, and balance disorder (loss of balance). It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain and to control it, you should have a balanced diet and exercise regularly. It is important to inform your doctor if you develop any unusual changes in mood or depression as it may lead to suicidal thoughts.
Before taking it, you should tell your doctor if you have kidney problems, depression, or suicidal thoughts and if you are pregnant or planning to become pregnant. You should not breastfeed while taking this medicine. Alcohol may increase the risk of seizures and worsen the side effects such as drowsiness and dizziness. Avoid alcohol while taking this medicine. Your kidney function may need to be tested often while taking this medicine.
Uses of Peramnel Tablet
Benefits of Peramnel Tablet
In Epilepsy/Seizures
Peramnel 4 Tablet slows down electrical signals in the brain which cause seizures (fits). It can also help reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. The medicine can allow you to do some activities that you would otherwise be forbidden or scared to do (such as swimming and driving). It can take a few weeks for this medicine to work (because the dose has to be increased slowly) and during this time you may still have seizures. Do not stop using this medicine even if you feel well until your doctor advises you to. Missing doses may trigger a seizure.
Side effects of Peramnel Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Peramnel
- Dizziness
- Sleepiness
- Fatigue
- Anger
- Fall
- Nausea
- Weight gain
- Vertigo
- Impaired coordination
- Altered walking
- Balance disorder (loss of balance)
How to use Peramnel Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Peramnel 4 Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Peramnel Tablet works
Peramnel 4 Tablet is an antiepileptic medication. It prevents seizures in patients with epilepsy by blocking a receptor in the brain known as the glutamate receptor, thereby suppressing the abnormal and excessive activity of the nerve cells in the brain.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Peramnel 4 Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Peramnel 4 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Peramnel 4 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Peramnel 4 Tablet may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Peramnel 4 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Peramnel 4 Tablet may be needed. Please consult your doctor.
Peramnel 4 Tablet should not be used in patients with severe liver disease.
Peramnel 4 Tablet should not be used in patients with severe liver disease.
Liver
CAUTION
Peramnel 4 Tablet should be used with caution in patients with liver disease. Dose adjustment of Peramnel 4 Tablet may be needed. Please consult your doctor.
Peramnel 4 Tablet should not be used in severe liver disease
Peramnel 4 Tablet should not be used in severe liver disease
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
- Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
- Some healthy tips to prevent seizures:
- Take a healthy diet along with regular exercise.
- Practice yoga every day.
- Get enough sleep at nighttime.
- Limit the use of screen time such as mobile/ laptop.
- Take your medication on time.
- Do not drive or do anything that requires mental focus until you know how Peramnel 4 Tablet affects you.
- It may cause weight gain. Hence, monitor your weight regularly.
- Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
- Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
Fact Box
Chemical Class
Bipyridines & Oligopyridines Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
AMPA glutamate receptor antagonist
Interaction with drugs
Taking Peramnel with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Perampanel may reduce the efficacy of Progesterone (Natural Micronized).
It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor m
Perampanel may reduce the efficacy of Progesterone.
It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may monitor your treat
Perampanel may reduce the efficacy of Dehydroepiandrosterone (Micronized).
It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor
Perampanel may reduce the efficacy of Dienogest.
It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may monitor your treatmen
Perampanel may reduce the efficacy of Progesterone (Natural Micronized).
It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor m
Patient concerns
FAQs
Does Peramnel 4 Tablet have abuse potential?
Yes, Peramnel 4 Tablet has abuse potential in addition to its rewarding psychological or physiological effects. If a patient has a history of drug abuse then monitoring for Peramnel 4 Tablet abuse should be done.
What are the most serious side effects of Peramnel 4 Tablet?
Peramnel 4 Tablet may cause some serious psychiatric and behavioral side effects such as aggression, hostility, irritability, anger, and suicidal and murderous thoughts.
What are the withdrawal symptoms of Peramnel 4 Tablet?
Peramnel 4 Tablet may cause physical dependence which means that suddenly stopping it may cause withdrawal symptoms which include anxiety, nervousness, irritability, fatigue, weakness, lethargy, mood swings, and sleeplessness.
Does Peramnel 4 Tablet cause weight gain?
Yes, Peramnel 4 Tablet may cause weight gain as a side effect of this medicine. Consult your doctor if it bothers you.
What should I avoid while taking Peramnel 4 Tablet?
Peramnel 4 Tablet may cause sleepiness and dizziness, so alcohol consumption should be avoided as it may make you more sleepy and dizzy. You should avoid driving and using heavy machinery until and unless you know how Peramnel 4 Tablet affects you. You should also avoid getting pregnant and breastfeeding your baby.
Can I stop taking Peramnel 4 Tablet on my own?
No, you should not stop taking Peramnel 4 Tablet without consulting your doctor. Sudden discontinuity of Peramnel 4 Tablet or significant dose reduction may cause occurrence of unpleasant effects.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1090-91.
- Perampanel. Woodcliff Lake, New Jersey: Eisai Inc.; 2012 [revised Apr. 2016]. [Accessed 22 Mar 2019] (online) Available from:
- Perampanel. Hatfield, UK: Eisai Manufacturing Limited; 2018. [Accessed 17 Jun. 2019] (online) Available from:
- Drugs.com. Perampanel. [Accessed 22 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
Marketer details
Name: Icon Life Sciences
Address: Icon Life Sciences, Div. Of Mesmer Pharmaceuticals, No.202/6, Lane In.30, Phase-II, IDA, Cherlapally, Hyderabad, 500 051 AP
Country of origin: India
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