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MBA, MD Pharmacology
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Periset 4 Tablet

Prescription Required
SALT COMPOSITION
Storage
Store below 30°C
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Product introduction

Periset 4 Tablet is an antiemetic medicine commonly used to control nausea and vomiting due to certain medical conditions like stomach upset. It is also used to prevent nausea and vomiting caused due to any surgery, cancer drug therapy, or radiotherapy.

Periset 4 Tablet may be used alone or with other medications and can be taken with or without food. Your doctor will suggest the appropriate dose depending on what you are taking it for. The first dose is normally taken before the start of surgery, chemotherapy, or radiotherapy. After these treatments, take any further doses as prescribed by your doctor (normally only for a few days at most). Take it regularly at the same time(s) each day to get the most benefit. Be careful not to take too much.

This medicine does not relieve other side effects associated with cancer treatments. Also, it has little effect on vomiting caused by motion sickness. The most common side effects of taking this medicine include headache, diarrhea, or constipation and feeling tired. These symptoms should disappear when you stop taking the medicine. However, if these side effects bother you or do not go away, your doctor may be able to suggest ways of preventing or reducing them. 

Before taking this medicine, tell your doctor if you have heart or liver problems or a blockage in your stomach or intestines. Also, tell your doctor about any other medicines you might be taking, especially medicines to treat epilepsy, heart problems, cancer, and depression. These may affect, or be affected by, this medicine. If you are pregnant or breastfeeding, ask for advice from your doctor.


Uses of Periset Tablet


Side effects of Periset Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Periset

  • Fatigue
  • Headache
  • Constipation
  • Diarrhea

How to use Periset Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Periset 4 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Periset Tablet works

Periset 4 Tablet is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.

Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Periset 4 Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Periset 4 Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Periset 4 Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Periset 4 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Periset 4 Tablet is safe to use in patients with kidney disease. No dose adjustment of Periset 4 Tablet is recommended.
However, inform your doctor if you have an underlying kidney disease. Limited information is available in patients taking this medicine for more than one day.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Periset 4 Tablet in patients with liver disease. Please consult your doctor.

What if you forget to take Periset Tablet?

If you miss a dose of Periset 4 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Periset 4 Tablet
₹5.7/Tablet
₹5.2/tablet
9% cheaper
₹5.4/tablet
5% cheaper
Zofer 4mg Tablet
Sun Pharmaceutical Industries Ltd
₹5.7/tablet
same price
Ondiphar Tablet
Biophar Lifesciences Pvt Ltd
₹4.17/tablet
27% cheaper
Ondem 4 Tablet
Alkem Laboratories Ltd
₹5.7/tablet
same price

Quick tips

  • You have been prescribed Periset 4 Tablet for prevention of nausea and vomiting caused after surgery or due to chemotherapy and radiotherapy.
  • It is fast-acting and starts working within 30 minutes.
  • If you vomit within one hour of taking a dose, take another dose.
  • Avoid heavy meals and try eating small nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.

Fact Box

Chemical Class
Carbazole Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Serotonin 5-HT3 Receptor Antagonists

Interaction with drugs

Taking Periset with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may affect heart rhythm and may be fatal. Do not consume Ondansetron with Amisulpride.
Concomitant use may affect heart rhythm and may be fatal. Do not consume Ondansetron with Amisulpride.
Concomitant use may affect heart rhythm and may be fatal. Do not consume Ondansetron with Amiodarone.
Concomitant use may affect heart rhythm and may be fatal. Do not consume Ondansetron with Amiodarone.
Concomitant use may affect heart rhythm and may be fatal. Do not consume Ondansetron with Aripiprazole.

Patient concerns

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SIR/MAM, I AM 5 MOnths pregnant.Taking periset MD ondensteron since 2nd months.Till date if I don't take medicine,too much vomiting starts. SO I HAVE TO CONTINUE.Is it safe to take it during pregnancy. I think my stomach habituated with this medicine. Pls suggest.I m feeling worried.
Dr. Megha Tuli
Obstetrics and Gynaecology
There is no dependence on this medicine. Do not worry. Very soon the vomiting will wean off and then you can leave the medicine.
What is side effect of primolut n
Dr. Megha Tuli
Obstetrics and Gynaecology
Bloating, pain abdomen, nausea, vomiting etc are common side of Primolut.
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User feedback


FAQs

How quickly does Periset 4 Tablet work?

Periset 4 Tablet starts working within half an hour to 2 hours. It dissolves rapidly into the bloodstream and starts showing its effect.

What are the side effects of Periset 4 Tablet?

The most common side effects of Periset 4 Tablet are constipation, diarrhea, fatigue and headache. However, these are usually not bothersome and resolve on their own after some time. Consult your doctor if these persist or worry you.

When should you take Periset 4 Tablet?

Periset 4 Tablet should be taken with a full glass of water, with or without food. It should be used exactly as per the dose and duration advised by the doctor. Usually, the first dose of Periset 4 Tablet is taken before the start of your surgery, chemotherapy or radiation treatment.

Is Periset 4 Tablet a steroid?

No, Periset 4 Tablet is an antiemetic and not a steroid. Periset 4 Tablet is a selective 5-HT3 receptor antagonist. It is prescribed for the prevention and treatment of nausea and vomiting which is commonly observed after surgery or due to cancer chemotherapy.

Does Periset 4 Tablet work for seasickness?

No, Periset 4 Tablet does not work for seasickness. This is because Periset 4 Tablet has very little effect on the nausea associated with motion sickness.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1341-42.
  2. Katzung BG. Histamine, Serotonin, & the Ergot Alkaloids. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 285
  3. Ondansetron. Portage, IN: Monosol Rx, LLC; 1991 [revised Jul. 2010]. [Accessed 28 Mar. 2019] (online) Available from:External Link
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Ondansetron. [Updated 2019 Feb 7]. [Accessed 20 Feb. 2020] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:External Link
  6. Ondansetron hydrochloride [Prescribing Information]. Research Triangle Park, NC: GlaxoSmithKline; 2016. [Accessed 25 Jul. 2024] (online) Available from: External Link

Marketer details

Name: Ipca Laboratories Ltd
Address: 142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra
Country of origin: India
Expires on or after: July, 2025

A licensed vendor partner from your nearest location will deliver Periset 4 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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