Perital 400mg Tablet is used to treat peripheral vascular disease (poor circulation to the arms and legs) and intermittent claudication (pain on walking or at rest caused by poor circulation to the legs). It works by increasing the blood flow to the arms and legs.

Perital 400mg Tablet medicine reduces cramping in the legs that occurs on walking in such patients. It also has beneficial effects in alcohol-related liver damage. Lifestyle modifications like smoking cessation and regular exercise can provide better results with this medicine.

It may cause headache, dizziness, dizziness, sleep disorder, and flushing as side effects. Patients taking this medicine should use caution while driving or operating machines.

Uses of Perital Tablet

Peripheral vascular disease
Intermittent claudication

Side effects of Perital Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Perital

Bloating
Diarrhea
Flushing (sense of warmth in the face, ears, neck and trunk)
Headache
Heartburn
Lightheadedness
Nausea
Stomach discomfort
Vomiting
Weakness
Dizziness
Sleep disorder

How to use Perital Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Perital 400mg Tablet is to be taken with food.

How Perital Tablet works

Perital 400mg Tablet is a peripheral vasodilator. It works by decreasing the thickness (viscosity) of blood, allowing it to pass more easily through the blood vessels. This effect is beneficial in peripheral vascular disease, where the blood vessels in the arms and legs are narrowed.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Perital 400mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Perital 400mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Perital 400mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Perital 400mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Perital 400mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Perital 400mg Tablet may be needed. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Perital 400mg Tablet in patients with liver disease. Please consult your doctor.

What if you forget to take Perital Tablet?

If you miss a dose of Perital 400mg Tablet, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Perital 400mg Tablet

₹7.43/Tablet

Cabaza Tablet

Jolly Healthcare

₹11.1/tablet

49% costlier

Flowpent 400mg Tablet

Abbott

₹2.76/tablet

63% cheaper

Flexital 400mg Tablet

Sun Pharmaceutical Industries Ltd

₹8.29/tablet

12% costlier

Kinetal 400mg Tablet

Cipla Ltd

₹2.77/tablet

63% cheaper

RB FLEX 400MG TABLET

Torrent Pharmaceuticals Ltd

₹2.69/tablet

64% cheaper

Quick tips

Take it as per dose and duration suggested by your doctor.
Do not drive or perform activities that require mental focus until you know how Perital 400mg Tablet affects you.
Your doctor may get regular blood tests done to monitor liver function while taking this medicine.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Take it with food, preferably at the same time everyday to avoid missing a dose.

Fact Box

Chemical Class

Methylxanthine Derivative

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Hemorrheologic Agents

Interaction with drugs

Taking Perital with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Ciprofloxacin (Oral Route) Severe

Concurrent use may cause severe headaches. Ciprofloxacin may raise blood levels of Pentoxifylline. If concurrent use is essential, your doctor may monitor your treatment and adjust... More

Ciprofloxacin (Injection Route) Severe

Concurrent use may cause severe headaches. Ciprofloxacin may raise blood levels of Pentoxifylline. If concurrent use is essential, your doctor may monitor your treatment and adjust... More

Aminophylline (Oral Route) Severe

Pentoxifylline may raise blood levels of Aminophylline. Do not consume Aminophylline with Pentoxifylline. If concurrent use is essential, watch out for symptoms such as nausea, pa... More

Phenindione (Oral Route) Severe

Concurrent use may increase the risk of bleeding. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Aminophylline (Oral Route) Severe

Pentoxifylline may raise blood levels of Aminophylline. Do not consume Aminophylline with Pentoxifylline. If concurrent use is essential, watch out for symptoms such as nausea, pa... More

View all drug interactions

Patient concerns

What is medicine for claudication

Dr. Jyoti Kapoor Madan

Psychiatry

Please consult a vascular surgeon

Having diabetes ,hypertension amd joint pain since past 5-6 yr by medication diabetes and hyoertension are controlled but peripheral neuropathy of both lower limb also associated with peripheral vascular disease of lower limbs best treatmrnt where and from which departnent??

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED. ALWAYS IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you SHOULD not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

Sir, madam I have been suffering from pain in my right ankle accompanied by swelling. I could also feel the pain in my hips as well. I suspect this to be peripheral vascular disease, since i frequently get the cramp whenever I walk or do physical activity in my right ankle.I only feel relieved when I take tablets like Pynor. Please suggest some suggest medication. Thank you.

Dr. Aanchal Maheshwari

Ayurveda

You better consult once with an Ayurvedic physician in person before starting the treatment

User feedback

Patients taking Perital 400mg Tablet

Twice A Day

75%

Once A Day

17%

Thrice A Day

What are you using Perital Tablet for?

Others

100%

How much was the improvement?

Excellent

100%

What were the side-effects while using Perital 400mg Tablet?

No Side Effec*

100%

*No Side Effect

How do you take Perital Tablet?

With or witho*

100%

*With or without food

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Katzung BG, Chatterjee K. Vasodilator & the Treatment of Angina Pectoris. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 205.
Gersh BJ, Opie LH. Which Therapy for Which Condition? In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 528.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1089-90.
Pentoxifylline. Guildford, Surrey: SANOFI; 2002 [revised 25 May 2016]. [Accessed 25 Jan. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Pentoxifylline. [Updated 2018 Oct 31]. [Accessed 19 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
Pentoxifylline [Patient Information Leaflet]. Ankleshwar: Gujarat: Sanofi India Limited; 2015. [Accessed 06 Apr. 2024] (online) Available from:

Marketer details

Name: Pericles Pharma

Address: B-702 Aaryan Euphoria, opp. Kargil petrol pump, Gujarat 380061

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.