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Last updated
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Pexibrus 37.5mg Tablet

Prescription Required

Product introduction

Pexibrus 37.5mg Tablet is a type of antidepressant belonging to the selective serotonin reuptake inhibitor (SSRI) group of medicines. It is widely prescribed to treat depression and anxiety-related conditions like obsessive-compulsive disorder, and panic disorder.

Pexibrus 37.5mg Tablet helps many people to recover from depression by improving their mood and relieving anxiety and tension. It can be taken with or without food. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your symptoms.

Your doctor may start you on a lower dose and increase it gradually. Do not change the dose or stop taking it without talking to your doctor, even if you feel well. Doing so may make your condition worse or you may suffer from unpleasant withdrawal symptoms (anxiety, restlessness, palpitations, dizziness, sleep disturbances, etc).

To get the most benefit, take this medicine regularly at the same time each day. Your doctor may advise you to take it in the morning if you have trouble sleeping. It may take a few weeks before you start feeling better. Let your doctor know if you do not see any improvement even after 4 weeks.

Some common side effects of Pexibrus 37.5mg Tablet include nausea, fatigue, dry mouth, loss of appetite, increased sweating, dizziness, nervousness, tremors, insomnia (difficulty in sleeping), and constipation. Sexual side effects like decreased sexual drive, delayed ejaculation, and erectile dysfunction may also be seen. Let your doctor know straight away if you develop any sudden worsening of mood or any thoughts about harming yourself.

Before taking this medicine, you should tell your doctor if you have epilepsy (seizure disorder or fits), diabetes, liver or kidney disease, heart problems, or glaucoma. These may affect your treatment. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines may affect the way it works, especially other antidepressants and medicines called MAO inhibitors. Please tell your doctor about all the medicines you are taking to make sure you are safe.

Benefits of Pexibrus Tablet

In Treatment of Panic disorder

Pexibrus 37.5mg Tablet can help relieve symptoms of many panic disorders including panic attacks. It can help you feel calmer and improve your ability to deal with problems. Do not stop taking it, even when you feel better, unless your doctor advises you to.

Side effects of Pexibrus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pexibrus

  • Nausea
  • Fatigue
  • Dryness in mouth
  • Loss of appetite
  • Increased sweating
  • Dizziness
  • Nervousness
  • Tremors
  • Low sexual desire
  • Insomnia (difficulty in sleeping)
  • Confusion
  • Constipation
  • Erectile dysfunction
  • Delayed ejaculation
  • Decreased libido

How to use Pexibrus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pexibrus 37.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Pexibrus Tablet works

Pexibrus 37.5mg Tablet is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It works by increasing the levels of serotonin, a chemical messenger in the brain. This improves mood and physical symptoms of depression and also relieves symptoms of panic disorder, anxiety, and obsessive-compulsive disorder.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Pexibrus 37.5mg Tablet.
Pregnancy
UNSAFE
Pexibrus 37.5mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Pexibrus 37.5mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Pexibrus 37.5mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Pexibrus 37.5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Pexibrus 37.5mg Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Pexibrus 37.5mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Pexibrus 37.5mg Tablet may be needed. Please consult your doctor.

What if you forget to take Pexibrus Tablet?

If you miss a dose of Pexibrus 37.5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Pexibrus 37.5mg Tablet
₹27.2/Tablet
Paxotus 37.5mg Tablet
Emcure Pharmaceuticals Ltd
₹33.55/tablet
23% costlier
Patroxta 37.5mg Tablet
Arinna Lifescience Pvt Ltd
₹33.82/tablet
24% costlier
Cnpaxet 37.5mg Tablet
CNX Healthcare Pvt Ltd
₹26.8/tablet
1% cheaper
₹17.3/tablet
36% cheaper
Xepar 37.5mg Tablet
Consern Pharma Limited
₹17.3/tablet
36% cheaper

Quick tips

  • It can take 2-3 weeks for Pexibrus 37.5mg Tablet to start working.
  • Do not stop treatment suddenly as this may cause upset stomach, flu-like withdrawal symptoms and sleep disturbance.
  • If your doctor asks you to stop Pexibrus 37.5mg Tablet, you should reduce the dose slowly over 4 weeks.
  • Avoid consuming alcohol when taking Pexibrus 37.5mg Tablet, as it may cause excessive drowsiness and calmness.
  • The addiction/dependence potential of Pexibrus 37.5mg Tablet is very less.
  • It can take 2-3 weeks for Pexibrus 37.5mg Tablet to start working.
  • Do not stop treatment suddenly as this may cause upset stomach, flu-like withdrawal symptoms and sleep disturbance.
  • If your doctor asks you to stop Pexibrus 37.5mg Tablet, you should reduce the dose slowly over 4 weeks.
  • Avoid consuming alcohol when taking Pexibrus 37.5mg Tablet, as it may cause excessive drowsiness and calmness.
  • The addiction/dependence potential of Pexibrus 37.5mg Tablet is very less.

Fact Box

Chemical Class
Phenylpiperidine Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Selective Seretonin Reuptake Inhibitors (SSRIs)

Interaction with drugs

Taking Pexibrus with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may increase the risk of recurrent breast cancer. Do not consume Tamoxifen with Paroxetine.
Concomitant use may cause an increase in blood serotonin levels. Patients may experience agitation, increased body temperature, fast heartbeat, muscle rigidity, and loss of coordin... More
Concomitant use may affect heart rhythm and can be fatal. Do not consume Moclobemide with Paroxetine. If Moclobemide is essential, ensure a gap of at least 1 week after discontinu... More
Concurrent use may cause fatal rise in blood serotonin levels. Avoid concurrent use unless your doctor considers it safe.
Concurrent use may cause serotonin syndrome. If concurrent use is essential, watch out for symptoms of serotonin syndrome such as tremors, fever, diarrhea or agitation and consult... More

Patient concerns

arrow
I have Obsessive compulsive Disorder. Prescribe the medication.
Dr. Deepak Kumar Soni
Ayurveda
Hi Kindly share your symptoms of your Problem
how to tackle depression and post traumal stress disorder?
Dr. Jyoti Kapoor Madan
Psychiatry
Psychiatric evaluation is based on history, clinical symptoms, personality factors, ongoing psychosocial stressors and frequency and severity of symptoms. It requires direct interaction with the patient on a regular basis. Once diagnosed, a management plan is formed based on intensity and frequency of symptoms and associated biological and psycho social factors. A complete solution to ones problems in a single question is thus not possible. Internet will give you generalised tips and tricks but they are hardly of any use. I suggest you to visit a psychiatrist in your vicinity for clinical evaluation.
arrow

FAQs

After how many days of taking Pexibrus 37.5mg Tablet will I start feeling better?

You may start to see an improvement in your symptoms after 1-2 weeks of starting the treatment. In case you do not see any improvement, do not stop the medicine and consult your doctor. It may take around 4-6 weeks to see the full benefits of the medicine.

I feel that my symptoms have worsened after having started taking Pexibrus 37.5mg Tablet. Can I stop it on my own or do I need to consult the doctor?

No, do not stop taking Pexibrus 37.5mg Tablet abruptly, without consulting your doctor. This is a common problem with Pexibrus 37.5mg Tablet that initially you may feel that your symptoms have worsened but the benefits start appearing after 1-2 weeks. If the worsening does not improve even after 1-2 weeks, you must consult your doctor.

Can Pexibrus 37.5mg Tablet affect my sex life?

Yes, Pexibrus 37.5mg Tablet use may affect your sex life. It can cause decreased sexual desire and inability to reach orgasm in both men and women. Additionally, men may even experience abnormal erection and ejaculation.

What is the effect of Pexibrus 37.5mg Tablet on children?

Pexibrus 37.5mg Tablet should not be used in children under 18 years of age. The reason being, patients under 18 have an increased risk of experiencing side effects such as suicidal thoughts, aggression, oppositional behavior and anger when they take Pexibrus 37.5mg Tablet. If your doctor has prescribed Pexibrus 37.5mg Tablet for your child and you are worried about these side effects, discuss it with your doctor.

I have been taking tamoxifen for breast cancer. Can I take Pexibrus 37.5mg Tablet with it?

No, you should not take Pexibrus 37.5mg Tablet if you are receiving tamoxifen. Tamoxifen often causes hot flashes (episodes of feeling extremely hot), which can be treated with Pexibrus 37.5mg Tablet. But Pexibrus 37.5mg Tablet may reduce the effectiveness of tamoxifen and can lead to recurrence of breast cancer.

Do I need to be careful while taking Pexibrus 37.5mg Tablet if I am a diabetic?

Yes, you need to be careful while taking this medicine if you are a diabetic. Pexibrus 37.5mg Tablet may alter your blood sugar levels and your dose of insulin or antidiabetic medicines may need adjustment. Talk to your doctor regarding this and keep a regular check on your blood sugar levels.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Stahl SM, editor. Paroxetine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 513-19.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1060-69.
  3. Paroxetine.Miami, Florida:Noven Therapeutics; 2003 [revised 06-2013]. [Accessed 25 Mar 2019] (online) Available from:External Link
  4. Chaves RG, Lamounier GA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 25 Mar. 2019] (online) Available from:External Link
  5. Paroxetine. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2008 [revised 25 Nov. 2018]. [Accessed 25 Mar. 2019] (online) Available from:External Link
  6. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Paroxetine. [Updated 2019 Oct 23]. [Accessed 20 Feb. 2020] (online) Available from:External Link
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:External Link
  8. Paroxetine [Product Monograph]. Mississauga, Ontario: GlaxoSmithKline Inc.; 2022. [Accessed 03 Aug. 2023] (online) Available from:External Link

Marketer details

Name: Med Manor Organics Pvt Ltd
Address: 16-11-477/45, Dilsukh Nagar, Hyderabad-500036, Telangana, India.
Country of origin: India

272
Inclusive of all taxes
MRP275  1% OFF
10.0 tablets in 1 strip
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