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MBA, MD Pharmacology
Last updated
29 Nov 2023 | 07:06 PM (IST)

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Phiof MZ Oral Suspension


Product introduction

Phiof MZ Oral Suspension is given to children for the treatment of bacterial infections of the teeth, lungs, gastrointestinal tract, urinary tract, and genital tract. This medicine is also given as an empirical antibiotic for infected diarrhea mixed with blood and serious infections like peritonitis.

Give Phiof MZ Oral Suspension to your child orally, preferably at a fixed time, either before or after meals. In case your child develops a stomach upset, prefer giving it with meals. Generally, this medicine is prescribed to be given two times a day, in the morning and evening. If your child vomits within 30 minutes of intake, repeat the same dose but do not double the dose if it is time for the next dose. Never change the dose, time, and way prescribed by the doctor since these depend upon the type and severity of the infection, your child’s age, and body weight.

In some cases, this medicine may cause some minor and temporary side effects, including nausea, vomiting, weight loss, metallic taste, headache, loss of appetite, abdominal cramps, and mild skin rash. These side effects are temporary and recede when your child gets used to the medicine. In case the side effects persist or start bothering your child, consult your child’s doctor without any delay.

Narrate your child’s complete medical history to your child’s doctor, including any previous episode of allergy, heart problem, liver impairment, and kidney malfunction. This information is critical for dose alterations and for planning your child’s overall treatment.

Uses of Phiof MZ Oral Suspension

Benefits of Phiof MZ Oral Suspension

In Treatment of Bacterial infections

Phiof MZ Oral Suspension is an antibiotic medicine given to children for the treatment of a wide range of bacterial infections such as tooth abscess, gum infection, pneumonia, diarrhea, dysentery, peritonitis, burning sensation while passing urine, and certain genital tract infections. This medicine inhibits the growth of infection-causing bacteria by stopping it from multiplying. You may start seeing an improvement in the infection within 3 to 5 days of regular dosing. But, you must still finish the full course of the medicine and never stop it abruptly by yourself as that may worsen your child’s condition or cause infection recurrence.

Side effects of Phiof MZ Oral Suspension

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Phiof MZ

  • Vomiting
  • Nausea
  • Weight loss
  • Abdominal pain
  • Headache
  • Diarrhea
  • Loss of appetite
  • Dizziness
  • Insomnia (difficulty in sleeping)
  • Metallic taste
  • Urine discoloration

How to use Phiof MZ Oral Suspension

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Phiof MZ Oral Suspension may be taken with or without food, but it is better to take it at a fixed time.

How Phiof MZ Oral Suspension works

Phiof MZ Oral Suspension is a combination of three active ingredients. While two of its ingredients, namely ofloxacin and metronidazole are antibiotics, simethicone is a gas-absorbing agent that improves gastric tolerability of the combination. The antibiotic ingredients interfere with the genetic material of bacteria by impairing its DNA. This kills the infection-causing bacteria, preventing its growth and stopping the infection. On the other hand, Simethicone binds with the gas bubbles produced as a result of the other two ingredients or as a result of some other problem. By doing so, it aids in the removal of gases and provides relief in stomach pain and bloating.

Safety advice

Alcohol
UNSAFE
Consuming alcohol while taking Phiof MZ Oral Suspension may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
CONSULT YOUR DOCTOR
Phiof MZ Oral Suspension may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Phiof MZ Oral Suspension is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Phiof MZ Oral Suspension may cause side effects which could affect your ability to drive.
Phiof MZ Oral Suspension may make you feel sleepy, dizzy, confused. You may have hallucinations, fits (convulsions) or temporary eyesight problems (such as blurred or double vision) affecting your ability to drive.
Kidney
CAUTION
Phiof MZ Oral Suspension should be used with caution in patients with kidney disease. Dose adjustment of Phiof MZ Oral Suspension may be needed. Please consult your doctor.
Liver
CAUTION
Phiof MZ Oral Suspension should be used with caution in patients with severe liver disease. Dose adjustment of Phiof MZ Oral Suspension may be needed. Please consult your doctor.

What if you forget to take Phiof MZ Oral Suspension?

Do not panic. You can give the medicine as soon as you remember unless your child’s doctor has advised a specific regime for your child. However, you should skip the dose if the next scheduled dose is near. In case of any confusion, do consult your doctor and do not double the dose to catch up.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Phiof MZ Oral Suspension
₹88.1/Oral Suspension
Floact MZS Oral Suspension
Astakind Biotech Private Limited
₹65/oral suspension
28% cheaper
Oflohit MS Oral Suspension
Rosswelt Biosciences
₹70/oral suspension
22% cheaper
Snuflox-MS Oral Suspension
Alrosa Pharmaceuticals Pvt Ltd
₹62/oral suspension
31% cheaper
Erolfy M Oral Suspension
Serbia Molecules Pvt Ltd
₹79/oral suspension
12% cheaper
Ofclub-M Oral Suspension
Olamic Healthcare
₹67/oral suspension
26% cheaper

Quick tips

  • Diarrhea is a common side effect of this medicine. If it occurs, make sure your child drinks plenty of water.
  • Your child may have an altered taste or furry tongue (coating of Phiof MZ Oral Suspension on tongue) after taking Phiof MZ Oral Suspension. Eating citrus fruit or sipping plenty of water or fruit juice may help.
  • Do not give any calcium, magnesium, iron, vitamin, or antacid within 2 hours of taking Phiof MZ Oral Suspension as these can affect the absorption of the medicine.
  • Never use this medicine for the common cold and flu as they are caused by viruses and Phiof MZ Oral Suspension treats only bacterial infections.
  • Discontinue Phiof MZ Oral Suspension and inform the doctor immediately if your child develops a rash, itchy skin, swelling of face and mouth, or has difficulty in breathing.
  • Only give Phiof MZ Oral Suspension to your child for their current infection. Never save medicine for future illnesses.

Fact Box

Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL

Patient concerns

arrow
Scar on face due to bacterial infections
Dr. Atul Jain
Dermatology
Pic is not clear, plz visit for proper opinion
I have a history of recurring yeast and bacterial vaginosis infections.
Dr. Sonu Balhara Ahlawat
Obstetrics and Gynaecology
Tab metrogyl 500 mg twice a day x 5 days and tab fluconazole 150 mg three doses alternate days
arrow

FAQs

What should I tell the doctor before giving Phiof MZ Oral Suspension to my child?

You must tell the doctor if your child is suffering from heart disease, seizures, psychiatric disorders, diabetes, photoallergy (allergy from sunlight), neuromuscular disorders, rheumatoid arthritis, or genetic disorders involving blood vessels. This is because there is a possibility that Phiof MZ Oral Suspension may aggravate these conditions and result in complications.

Can Phiof MZ Oral Suspension be given along with cough and cold medicines?

No, do not give Phiof MZ Oral Suspension with cough and cold medicines. The reason being, one of the ingredients present in Phiof MZ Oral Suspension can interact with alcohol-containing medicines like cough syrups and can lead to disulfiram reaction, causing nausea, vomiting, flushing, dizziness, etc.

What if I give an overdose of Phiof MZ Oral Suspension by mistake?

An extra dose of Phiof MZ Oral Suspension is unlikely to harm. However, if you think you have given too much to your child, immediately speak to a doctor. Overdose may cause unwanted side effects such as seizures, tremors, severe headache, sudden weakness, blood cell abnormalities, and rapid and irregular heartbeat. Rush to your child’s doctor if you notice any of these symptoms.

What should I do if my child shows no improvement even after taking Phiof MZ Oral Suspension for the prescribed duration?

It could mean that Phiof MZ Oral Suspension is unable to kill the infection-causing bacteria. In such a case, visit your child’s doctor who may prescribe some other antibiotic that has a higher efficacy against the disease-causing bacteria. Remember, that sometimes, such antibiotics may have to be given by IV route (intravenous injection) in the hospital.

Can other medicines be given at the same time as Phiof MZ Oral Suspension?

Phiof MZ Oral Suspension can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Phiof MZ Oral Suspension. Also, check with your child’s doctor before giving any medicine to your child.

How should Phiof MZ Oral Suspension be stored?

Store Phiof MZ Oral Suspension at room temperature, in a dry place, away from direct heat and light. Children may accidentally consume medicines if they find them while playing around. So, make sure that all the medicines are kept away from their reach and sight.

Can I get my child vaccinated while on treatment with Phiof MZ Oral Suspension?

Antibiotics usually do not interfere with the ingredients in vaccines or cause a bad reaction in a child who has just been vaccinated. However, children taking antibiotics should not get vaccinated until they recover from the illness. As soon as your child feels better, the vaccine can be given.

My child has been passing red-brown urine ever since he started taking Phiof MZ Oral Suspension? Is it normal?

Phiof MZ Oral Suspension contains active ingredient metronidazole, which causes red-brown urine. It is not pathogenic but a side effect. It subsides once the medicine is stopped after the completion of the treatment.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Metronidazole [FDA Label]. Chicago, IL: G.D. Searle LLC; 2003. [Accessed 19 Jan. 2021] (online) Available from:External Link
  2. University of Michigan: C.S. Mott Children’s Hospital. Metronidazole. [Accessed 20 Jan. 2020] (online) Available from:External Link
  3. University of Michigan: C.S. Mott Children’s Hospital. Ofloxacin. [Accessed 20 Jan. 2020] (online) Available fromExternal Link
  4. Memorial Sloan Kettering Cancer Center. Ofloxacin (Systemic): Pediatric Medication. [Accessed 20 Jan. 2020] (online) Available from:External Link
  5. University of Michigan: C.S. Mott Children’s Hospital. Simethicone. [Accessed 20 Jan. 2020] (online) Available from:External Link
  6. Memorial Sloan Kettering Cancer Center. Simethicone. [Accessed 20 Jan. 2020] (online) Available from:External Link

Marketer details

Name: Newcrest Pharmaceuticals
Address: SCO-8, 1st Floor Green Estates, Oppo. ATS, Barwala Road, Derabassi, Sas Nagar, Sas Nagar-140507, Punjab, India
Country of origin: India

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Same salt composition:Ofloxacin (50mg), Metronidazole (120mg), Simethicone (10mg)
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