Pioryl 15 mg/2 mg Tablet
Prescription Required
View available alternative with same salt composition
Product introduction
Pioryl 15 mg/2 mg Tablet is a combination medicine that helps control blood sugar levels. This medicine is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Adequate sugar control lessens your risk of heart attack or stroke also.
Pioryl 15 mg/2 mg Tablet should be taken in the dose and duration as advised by your doctor. It must be taken with food to avoid stomach upset. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. Overdose may lead to low blood sugar (hypoglycemia).
Some people may develop a urinary tract infection, a bone fracture, or an increase in weight. However, these are temporary and usually subside on their own. If these do not resolve or bother you, please consult your doctor.
Before taking this medicine, inform your doctor if you have any kidney, liver or heart problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor will check your kidney function tests before starting treatment with it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects.
Uses of Pioryl Tablet
Benefits of Pioryl Tablet
In Treatment of Type 2 diabetes mellitus
Pioryl 15 mg/2 mg Tablet is a medicine that helps to control high blood glucose (sugar) levels. It helps get rid of extra glucose from your body through urine. It also improves the body’s response to the hormone insulin, which is responsible for regulating blood glucose (sugar) levels in our body. The insulin helps to lower your blood glucose levels and prevents them from rising after taking meals. You should keep taking it for as long as it is prescribed.
Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.
Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.
Side effects of Pioryl Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pioryl
- Urinary tract infection
How to use Pioryl Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pioryl 15 mg/2 mg Tablet should be taken with or after food.
How Pioryl Tablet works
Pioryl 15 mg/2 mg Tablet is a combination of pioglitazone and glimepiride. Pioglitazone is a thiazolidinedione that works by increasing the body's sensitivity to insulin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Together, they provide better control of blood sugar.
Safety advice
Alcohol
CAUTION
Alcohol should be used with caution while taking Pioryl 15 mg/2 mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
The safety of Pioryl 15 mg/2 mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding
CONSULT YOUR DOCTOR
Pioryl 15 mg/2 mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Monitoring of the breastfed infant's blood glucose is advisable during maternal therapy with Pioryl 15 mg/2 mg Tablet
Monitoring of the breastfed infant's blood glucose is advisable during maternal therapy with Pioryl 15 mg/2 mg Tablet
Driving
UNSAFE
Pioryl 15 mg/2 mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Pioryl 15 mg/2 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Pioryl 15 mg/2 mg Tablet is not recommended in patients with severe kidney disease. These patients can experience very low blood sugar levels which may become normal after a long time.
Use of Pioryl 15 mg/2 mg Tablet is not recommended in patients with severe kidney disease. These patients can experience very low blood sugar levels which may become normal after a long time.
Liver
CAUTION
Pioryl 15 mg/2 mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Pioryl 15 mg/2 mg Tablet is not recommended in patients with severe liver disease. These patients can experience very low blood sugar levels which may become normal after a long time.
Use of Pioryl 15 mg/2 mg Tablet is not recommended in patients with severe liver disease. These patients can experience very low blood sugar levels which may become normal after a long time.
What if you forget to take Pioryl Tablet?
If you miss a dose of Pioryl 15 mg/2 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Pioryl 15 mg/2 mg Tablet
₹6.46/Tablet
Pioglar-G Tablet
Sun Pharmaceutical Industries Ltd
₹15.5/tablet
140% costlier
Pozitiv G 15mg/2mg Tablet
Franco-Indian Pharmaceuticals Pvt Ltd
₹9.66/tablet
50% costlier
Quick tips
- Take it as per the dose and duration prescribed by your doctor.
- Take it with the first main meal of the day (usually breakfast).
- It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
- Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxiety.
- Inform your doctor if you notice weight gain, shortness of breath, irregular heartbeat, or any abnormal swelling.
- Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
Fact Box
Habit Forming
No
Therapeutic Class
ANTI DIABETIC
Patient concerns
FAQs
What is Pioryl 15 mg/2 mg Tablet used for?
Pioryl 15 mg/2 mg Tablet is a prescription medicine for adults with type 2 diabetes. It helps lower blood sugar levels when diet and exercise alone are not enough, reducing the risk of diabetes complications.
Who should not take Pioryl 15 mg/2 mg Tablet?
Individuals should not take Pioryl 15 mg/2 mg Tablet if they have type 1 diabetes, diabetic ketoacidosis, severe heart failure, bladder cancer, serious liver problems, or if they are allergic to either pioglitazone, glimepiride, or other sulfonylurea medicines.
Can Pioryl 15 mg/2 mg Tablet cause heart problems?
Yes, pioglitazone (present in Pioryl 15 mg/2 mg Tablet) may cause fluid retention, which can lead to or worsen heart failure. You should inform your doctor immediately if you develop shortness of breath, rapid weight gain, or swelling in your legs or ankles.
Is there a risk of bladder cancer with Pioryl 15 mg/2 mg Tablet?
Some studies suggest that long-term use of Pioryl 15 mg/2 mg Tablet may be linked to an increased risk of bladder cancer. You should tell your doctor if you have a history of bladder cancer or notice blood in your urine.
Can Pioryl 15 mg/2 mg Tablet cause liver problems?
Yes, Pioryl 15 mg/2 mg Tablet can rarely cause liver injury. You should contact your doctor right away if you experience symptoms such as unusual tiredness, loss of appetite, dark urine, or yellowing of the skin, or eyes.
Are there risks of bone fractures with Pioryl 15 mg/2 mg Tablet use?
Yes, Pioryl 15 mg/2 mg Tablet may increase the risk of bone fractures, particularly in women. Your doctor may recommend bone health monitoring during treatment.
What should I tell my doctor before starting Pioryl 15 mg/2 mg Tablet?
Before starting Pioryl 15 mg/2 mg Tablet, you should inform your doctor if you have heart disease, liver problems, kidney disease, bladder cancer, bone health concerns, or a history of severe low blood sugar.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Quinn CE, Hamilton PK, Lockhart CJ, et al. Thiazolidinediones: Effects on insulin resistance and the cardiovascular system. Br J Pharmacol. 2008;153(4):636-45. [Accessed 21 Jan. 2019] (online) Available from:
- Pioglitazone. County Wicklow, Ireland: Takeda Ireland Limited. [Accessed 08 Apr. 2019] (online) Available from:
- Pioglitazone And Glimepiride. Greifswald, Germany: Cheplapharm Arzneimittel GmbH. [Accessed 27 Jan. 2026] (online). Available from:
Marketer details
Name: Panacea Biotec Pharma Ltd
Address: B-1,Extn/A-27,Mohan Co-operative Industrial Estate Mathura Road, New Delhi-110044
Country of origin: India
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Available alternative with same salt composition
Pioglar-G Tablet
strip of 10 tablets
by Sun Pharmaceutical Industries Ltd
Get by 5pm
₹155
8% off
Pioglitazone (15mg) + Glimepiride (2mg)